1. Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients.
- Author
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Riis PT, Saunte DM, Sigsgaard V, Villani AP, Guillem P, Pascual JC, Kappe NN, Vanlaerhoven AMJD, van der Zee HH, Prens EP, El-Domyati M, Abdel-Wahab H, Moftah N, Abdelghani R, Agut-Busquet E, Romaní J, Hlela C, van den Worm L, Bettoli V, Calamo G, Gürer MA, Beksaç B, Matusiak L, Glowaczewska A, Szepietowski JC, Emtestam L, Lapins J, Kottb HR, Fatani M, Weibel L, Theiler M, Delage-Toriel M, Lam TTH, Nassif A, Becherel PA, Dolenc-Voljc M, Doss N, Bouazzi D, Benhadou F, Del Marmol V, and Jemec GBE
- Subjects
- Acne Vulgaris epidemiology, Administration, Cutaneous, Administration, Oral, Adolescent, Body Mass Index, Child, Clindamycin administration & dosage, Comorbidity, Cross-Sectional Studies, Drug Therapy, Combination methods, Female, Hidradenitis Suppurativa epidemiology, Hirsutism epidemiology, Humans, Male, Pilonidal Sinus epidemiology, Resorcinols administration & dosage, Rifampin administration & dosage, Risk Factors, Severity of Illness Index, Tetracycline administration & dosage, Treatment Outcome, Young Adult, Anti-Bacterial Agents administration & dosage, Dermatologic Surgical Procedures, Hidradenitis Suppurativa therapy, Obesity epidemiology, Smoking epidemiology
- Abstract
Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.
- Published
- 2020
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