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High-voltage (HV) pulse generators (PGs) are the core of pulsed electric field applications. Applying HV pulses produces electrical pores in a biological cell membrane, in which if the size of the pores increases beyond a critical size, the cell will not survive. This paper proposes a new HV-PG based on the modular multilevel converter with full-bridge submodules (FB-SMs). In order to alleviate the need of complicated sensorless or sensor-based voltage balancing techniques for the FB-SM capacitors, a dedicated self-regulating charging circuit is connected across each FB-SM capacitor. The individual capacitor charging voltage level is obtained from three successive stages, namely, convert the low-voltage dc input voltage to a high-frequency square ac voltage, increase the ac voltage level via a nanocrystalline step-up transformer, and rectify the secondary transformer ac voltage via a diode FB rectifier. The HV bipolar pulses are formed across the load in a fourth stage through series connected FB-SMs. The flexibility of inserting and bypassing the FB-SM capacitors allows the proposed topology to generate different pulse-waveform shapes, including rectangular waveforms with specifically reduced dv/dt and ramp pulses. The practical results, from a scaled-down experimental rig with five FB-SMs and a 1-kV peak-to-peak pulse output, validate the proposed topology. [ABSTRACT FROM PUBLISHER]

This paper proposes a medium-/high-voltage high-power hybrid modular dc–dc converter to interconnect two different dc-voltage levels in medium-/high-voltage dc grids. The converter consists of half-bridge submodules (SMs) rated at a moderate voltage level, i.e., series connection of semiconductor devices is avoided while connecting two high dc-voltage levels. The proposed architecture provides self-balancing operation, i.e., unlike conventional modular converters, no need for capacitor voltage measurement, which enhances the system reliability and simplicity. Sequential charging/discharging of SMs capacitors is adopted in the proposed approach to ensure a self-balanced operation. The proposed architecture can provide a high conversion ratio as well as power transfer in both directions, i.e., bidirectional dc–dc converter. Detailed illustration of the proposed approach operational concept, design, and overall control system is presented. Simulation and experimental results are presented to show the viability of the proposed configuration and validate the claims. [ABSTRACT FROM AUTHOR]