1. Examination of inequalities in HIV/AIDS mortality in the United States from a fundamental cause perspective
- Author
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Rubin, Marcie S., Colen, Cynthia G., and Link, Bruce G.
- Subjects
Highly active antiretroviral therapy -- Patient outcomes ,Highly active antiretroviral therapy -- Demographic aspects ,Highly active antiretroviral therapy -- Health aspects ,HIV infection -- Drug therapy ,HIV infection -- Demographic aspects ,HIV infection -- Patient outcomes ,HIV infection -- Research ,Discrimination in medical care -- Demographic aspects ,Mortality -- United States ,Mortality -- Risk factors ,Mortality -- Research ,Government ,Health care industry - Abstract
Objectives. We examined changes in socioeconomic status (SES) and Black to White inequalities in HIV/AIDS mortality in the United States before and after the introduction of highly active antiretroviral therapy (HAART). Methods. Taking a fundamental cause perspective, we used negative binomial regression to analyze trends in county-level gender-, race-, and age-specific HIV/ AIDS mortality rates among those aged 15 to 64 years during the period 1987-2005. Results. Although HIV/AIDS mortality rates decreased once HAART became available, the declines were not uniformly distributed among population groups. The associations between SES and HIV/AIDS mortality and between race and HIV/AIDS mortality, although present in the pre-HAART period, were significantly greater in the peri- and post-HAART periods, with higher SES and White race associated with the greatest declines in mortality during the post-HAART period. Conclusions. Our findings support the fundamental cause hypothesis, as the introduction of a life-extending treatment exacerbated inequalities in HIV/AIDS mortality by SES and by race. In addition to a strong focus on factors that improve overall population health, more effective public health interventions and policies would facilitate an equitable distribution of health-enhancing innovations. (Am J Public Health. 2010;100:1053-1059. doi: 10.2105/AJPH.2009.170241)
- Published
- 2010