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Monazite is a key accessory mineral for metamorphic geochronology, but interpretation of its complex chemical and age zoning acquired during high-temperature metamorphism and anatexis remains a challenge. We investigate the petrology, pressure-temperature and timing of metamorphism in pelitic and psammitic granulites that contain monazite from the Greater Himalayan Crystalline Complex (GHC) in Dinggye, southern Tibet. These rocks underwent isothermal decompression from pressure of >10 kbar to ~5 kbar at temperatures of 750-830 °C, and recorded three metamorphic stages at kyanite (M), sillimanite (M) and cordierite-spinel grade (M). Monazite and zircon crystals were dated by microbeam techniques either as grain separates or in thin sections. U-Th-Pb ages are linked to specific conditions of mineral growth on the basis of zoning patterns, trace element signatures, index mineral inclusions (melt inclusions, sillimanite and K-feldspar) in dated domains and textural relationships with co-existing minerals. The results show that inherited domains (500-400 Ma) are preserved in monazite even at granulite-facies conditions. Few monazites or zircon yield ages related to the M-stage (~30-29 Ma), possibly corresponding to prograde melting by muscovite dehydration. During the early stage of isothermal decompression, inherited or prograde monazites in most samples were dissolved in the melt produced by biotite dehydration-melting. Most monazite grains crystallized from melt toward the end of decompression (M-stage, 21-19 Ma) and are chemically related to garnet breakdown reactions. Another peak of monazite growth occurred at final melt crystallization (~15 Ma), and these monazite grains are unzoned and are homogeneous in composition. In a regional context, our pressure-temperature-time data constrains peak high-pressure metamorphism within the GHC to ~30-29 Ma in Dinggye Himalaya. Our results are in line with a melt-assisted exhumation of the GHC rocks. [ABSTRACT FROM AUTHOR]