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Your search keyword '"Heiken, Hans"' showing total 2 results
Start Over Author "Heiken, Hans" Topic hiv drug resistance
2 results on '"Heiken, Hans"'

1. Virologic outcomes of switching to boosted darunavir plus dolutegravir with respect to history of drug resistance

Author

Wolf, Eva, Boesecke, Christoph, Balogh, Annamaria, Bidner, Helen, Cordes, Christiane, Heiken, Hans, Krznaric, Ivanka, Kümmerle, Tim, Stellbrink, Hans-Jürgen, Schneider, Jochen, and Spinner, Christoph D.

Subjects
Male, Anti-HIV Agents, Pyridones, Short Report, Drug Resistance, HIV Infections, Protease inhibitors, Middle Aged, Piperazines, Dolutegravir, HIV drug resistance, Oxazines, Integrase inhibitors, HIV-1, Humans, Female, Heterocyclic Compounds, 3-Ring, Darunavir
Abstract

Objective The DUALIS study showed that switching to boosted darunavir (bDRV) plus dolutegravir (DTG; 2DR) was non-inferior to continuous bDRV plus 2 nucleoside/nucleotide reverse-transcriptase inhibitors (NRTIs; 3DR) in treatment-experienced virologically suppressed people living with HIV (PLWH). We analyzed virologic outcomes with respect to treatment history and HIV drug resistance. Design Post hoc analysis of a randomized trial. Methods Main inclusion criteria were an HIV RNA level

Published
2021

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