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Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a rare subtype of Hodgkin lymphoma (HL) characterized by a distinct morphology, an older median age at onset, less incidence of mediastinal involvement, more frequent relapse and better prognosis as compared to Classical-HL (CHL). In contrast to CHL, the tumor cell (LP cell) of NLPHL almost always retains its B cell phenotype and is a CD30 non-expresser. Due to its rarity, only a handful of studies on this entity are available in the literature. We present a short case series of 10 cases of NLPHL diagnosed in our institute over 10 years. A total of 10 cases of NLPHL were retrospectively accessed, re-evaluated and classified further, based on various morphological patterns and immunophenotypic expression. Morphological patterns were correlated with overall the prognosis. Our study showed peripheral lymph node localization and overall good outcome in these cases. We also came across two unique cases, one was of NLPHL with Rosai-Dorfman disease (RDD) and another was of composite lymphoma showing components of NLPHL and Diffuse Large B cell Lymphoma (DLBCL). [ABSTRACT FROM AUTHOR]

18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan is the imaging modality of choice in the management of lymphoma. However, 18F-FDG is a nonspecific tracer for tumoral metabolic activity and infective pathology, thus posing a challenge in accurate response assessment. Here, we present a case of Hodgkin's lymphoma, referred for staging PET/CT scan which showed FDG-avid disease in the mediastinum, and on interim 18F-FDG PET/CT in addition to the mediastinal mass lesion, a FDG-avid lesion was also noted in the spleen suggestive of disease progression. The biopsy report of the lesion was tuberculosis, which was masquerading as disease progression on interim 18F-FDG PET/CT. [ABSTRACT FROM AUTHOR]

Fibroids are rare in postmenopausal females. Torsion of pedunculated uterine fibroid is also a very rare occurrence in elderly females. We report a rare case of an 84-year-old multiparous, postmenopausal female, a treated case of non-Hodgkin's lymphoma, presenting with a large abdominal mass. The comparative positron emission tomography/computed tomography scan study of the patient revealed that a new mass in the abdomen and pelvis connected with the left adnexa with a pedicle and previously seen fibroid was not visualized on the present scan, thus raising suspicion of torsion of subserosal fibroid. Histopathology confirmed the diagnosis of fibroid. [ABSTRACT FROM AUTHOR]