1. [The liver transplant program of the Hospital General Universitario Gregorio Marañón: an analysis of the first 100 patients].
- Author
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Calleja Kempin J, Clemente Ricote G, Pérez Ferreiroa J, Bañares Cañizares R, Polo Melero JR, García Sabrido JL, Valdecantos Montes E, Olmedilla L, Santos L, and Pérez Peña J
- Subjects
- Adult, Aged, Chi-Square Distribution, Female, Graft Rejection prevention & control, Humans, Immunosuppression Therapy, Liver Diseases diagnosis, Liver Diseases surgery, Liver Transplantation methods, Male, Middle Aged, Postoperative Complications epidemiology, Spain epidemiology, Tissue Donors, Hospitals, General statistics & numerical data, Hospitals, University statistics & numerical data, Liver Transplantation statistics & numerical data
- Abstract
During a 3-year period between 1990 and 1993, 100 patients received orthotopic liver transplantation at the "Gregorio Marañón" University General Hospital. The mean age of the patients was relatively high (46.9 +/- 10 years), with an important number of cirrhotic patients (91%). The rate of primary liver failure was relatively low (4.5% of transplantations) although 12 cases with more than 55 years were included in the present series. Eleven retransplantations were performed, 8 for early failure of the graft and 3 for chronic failure. Postoperative complications of the graft were vascular in 9 cases, biliary in 17 cases, and acute rejection (cellular) in 70 patients, although only 50 of these patients required treatment with steroid boluses. Infections were diagnosed in 60 cases with 80% of major infections, 6 of them caused by Aspergillus fumigatus that were lethal in all the cases. Postoperative survival was 82%, 72%, 69% and 69% at 1 month, 6 months, 1 year and 2 years respectively.
- Published
- 1995