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Your search keyword '"C.-Y. Zheng"' showing total 7 results
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7 results on '"C.-Y. Zheng"'

1. [Investigation on status of dyslipidemia in Chinese females aged 35 years or above]

Author

M Y, Ma, X L, Chen, Z, Chen, X, Wang, L F, Zhang, S N, Li, C Y, Zheng, Y T, Kang, H H, Zhou, L, Chen, X, Cao, J H, Hu, and Z W, Wang

Subjects
Adult, China, Cross-Sectional Studies, Cardiovascular Diseases, Risk Factors, Prevalence, Humans, Female, Obesity, Middle Aged, Aged, Dyslipidemias, Retrospective Studies
Published
2022

3. [Association between body fat percentage, visceral fat index and cardiometabolic risk factor clustering among population aged 35 year old or over, in Tibet Autonomous Region and Xinjiang Uygur Autonomous Region]

Author

J L, Wang, Z, Chen, L F, Zhang, X, Wang, Y, Dong, J Y, Nie, C Y, Zheng, L, Shao, Y, Tian, and Z W, Wang

Subjects
Adult, Male, China, Intra-Abdominal Fat, Middle Aged, Tibet, Body Mass Index, ROC Curve, Risk Factors, Hypertension, Diabetes Mellitus, Prevalence, Humans, Female, Adiposity, Aged, Dyslipidemias
Published
2017

4. [Association between the types of obesity and the 10-year-coronary heart disease risk, in Tibet Autonomous Region and Xinjiang Uygur Autonomous Region]

Author

C Y, Zheng, Z W, Wang, Z, Chen, L F, Zhang, X, Wang, Y, Dong, J Y, Nie, J L, Wang, L, Shao, and Y, Tian

Subjects
Adult, Male, China, Coronary Disease, Middle Aged, Reference Standards, Tibet, Asian People, Psychological Distance, Risk Factors, Obesity, Abdominal, Ethnicity, Prevalence, Humans, Female, Obesity, Seasons, Aged
Published
2017

5. Regulation of surface and intracellular expression of CTLA-4 on human peripheral T cells

Author

X B, Wang, C Y, Zheng, R, Giscombe, and A K, Lefvert

Subjects
CD4-Positive T-Lymphocytes, Intracellular Fluid, Immunoconjugates, Base Sequence, Reverse Transcriptase Polymerase Chain Reaction, T-Lymphocytes, Cell Membrane, Receptors, Interleukin-2, CD8-Positive T-Lymphocytes, In Vitro Techniques, Flow Cytometry, Lymphocyte Activation, Antigens, Differentiation, Recombinant Proteins, Abatacept, Interferon-gamma, Gene Expression Regulation, Solubility, Antigens, CD, Concanavalin A, Humans, Interleukin-2, CTLA-4 Antigen, DNA Primers
Abstract

Cytotoxic T-lymphocyte-associated antigen (CTLA-4) is an important downregulator of T-cell activation. In order to analyze the expression and regulation of CTLA-4 on human peripheral T cells, CTLA-4 mRNA and protein expression were determined using analysis by reverse transcription-polymerase chain reaction (RT-PCR) and FACs, respectively. Intracellular CTLA-4 was constitutively expressed in unstimulated CD4+ and CD8+ T cells. Interleukin (IL)-2 induced a dose-dependent increase of both intracellular and surface expression of CTLA-4 (CD152). Most of the CD4+ and CD8+ cells expressing CTLA-4 also expressed CD25. Interferon (IFN)-gamma induced the upregulation of CTLA-4 expression via antigen-presenting cells (APC) activation. The CTLA-4delTM mRNA (550 bp) had a shorter half-life than the full length CTLA-4 mRNA and the expression was downregulated upon activation of the cells by treatment with IL-2. Given an inhibitory role of CTLA-4 and CD4+ CD25+ T cells in immune responses, the present findings suggest that IL-2-induced immunosuppression may result from its stimulatory effect of the CTLA-4 expression.

Published
2001

6. Transfection of chronic lymphocytic leukemic cells with myc and ras

Author

C Y, Zheng, L F, Skinnider, J, Xian, and A, Maksymiuk

Subjects
Cell Transformation, Neoplastic, Genes, ras, Phenotype, Karyotyping, Genes, myc, Tumor Cells, Cultured, Humans, Transfection, Leukemia, Lymphocytic, Chronic, B-Cell
Abstract

Thirty samples of cells from twenty-one cases of chronic lymphocytic leukemia (CLL) were transfected with myc and/or ras. Transformation, as assessed by growth in liquid culture and change in morphology, occurred in only one case. Colony culture in semi-solid media, however, does not occur with these cells. It would appear that the neoplastic genotype of CLL cells does not predispose the cells to readily transform, even with transfection with these two oncogenes.

Published
1992

7. Study on the Association of HLA With Malignant Lymphoma

Author

X. P. Xu, C. Y. Zheng, Q. H. Li, and C. Y. Wang

Subjects
Male, China, HLA-A Antigens, Lymphoma, business.industry, Immunology, HLA-C Antigens, General Medicine, Human leukocyte antigen, Phenotype, Malignant lymphoma, Epitopes, Antigen, Antigens, Neoplasm, HLA Antigens, HLA-B Antigens, Relative risk, Humans, Medicine, Female, Patient group, business, Han nationality
Abstract

The association of HLA with malignant lymphomas in 50 Chinese patients of the HAN nationality was investigated. The frequencies of antigens HLA-A and -C and the majority of HLA-B phenotypes were not significantly different between the patient and control groups, whereas the antigen frequency of HLA-B16 was increased significantly (P less than 0.025) in the patient group. The relative risk associated with HLA-B16 was 2.5694. The association of this antigen with malignant lymphoma might be unique for Oriental patients.

Published
1986

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