4 results on '"Eloísa Cervantes"'
Search Results
2. Antibiotic Prescribing in Children Hospitalized With COVID-19 and Multisystem Inflammatory Syndrome in Spain: Prevalence, Trends, and Associated Factors
- Author
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David Aguilera-Alonso, Cristina Epalza, Francisco José Sanz-Santaeufemia, Carlos Grasa, Sara Villanueva-Medina, Susana Melendo Pérez, Eloísa Cervantes Hernández, María Urretavizcaya-Martínez, Rosa Pino, Marisa Navarro Gómez, Javier Pilar Orive, Ana González Zárate, Paula Vidal Lana, Raúl González Montero, Sara Ruiz González, Cristina Calvo, María Isabel Iglesias-Bouzas, José Manuel Caro-Teller, Sara Domínguez-Rodríguez, Álvaro Ballesteros, Juan Mesa, Elena Cobos-Carrascosa, Alfredo Tagarro, and Cinta Moraleda
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SARS-CoV-2 ,Pediatría ,antibiotic stewardship ,COVID-19 ,General Medicine ,Systemic Inflammatory Response Syndrome ,Virus ,Anti-Bacterial Agents ,Tratamiento médico ,Infectious Diseases ,Antibacterianos ,bacterial infections ,children ,Spain ,Pediatrics, Perinatology and Child Health ,Prevalence ,Humans ,Child - Abstract
The SARS-CoV-2 pandemic has caused an increase in antibiotic use in different settings. We describe the antibiotic prescribing prevalence, associated factors and trends, as well as concomitant bacterial infections in children hospitalized with COVID-19 or multisystemic inflammatory syndrome related to SARS-CoV-2 in Spain. Instituto de Salud Carlos III (ISCIII) Unión Europea-Fondos FEDER (proyecto PI20/00095) Ministerio de Sanidad/ISCIII Sociedad Española de Pediatría Fondos FEDER (Contrato Río Hortega CM18/00100 y CM19/00015 ) 5.235 JCR (2021) Q1, 14/130 Pediatrics 1.236 SJR (2021) Q1, 66/301 Infectious Diseases No data IDR 2020 UEM
- Published
- 2021
3. Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population
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Serena Villaverde, Sara Domínguez-Rodríguez, Gema Sabrido, Conchita Pérez-Jorge, Marta Plata, María Pilar Romero, Carlos Daniel Grasa, Ana Belén Jiménez, Elena Heras, Antonio Broncano, María del Mar Núñez, Marta Illán, Paloma Merino, Beatriz Soto, David Molina-Arana, Amanda Bermejo, Pablo Mendoza, Manuel Gijón, Begoña Pérez-Moneo, Cinta Moraleda, Alfredo Tagarro, Cristina Calvo, Ma José Mellado, Paula Rodríguez-Molino, Teresa del Rosal, Mar Santos, Marisa Navarro, Elena Rincón, Begoña Santiago, Jesús Saavedra-Lozano, David Aguilera-Alonso, Cristina Epalza, Daniel Blázquez-Gamero, Sara Villanueva, Pablo Rojo, Gero Calleja, J.A. Alonso, Mercedes de la Torre, F.J. Sanz-Santaeufemia, M.I. Iglesias, B. Herrero, M. Alonso, Toni Soriano-Arandes, J.M. Pujol, Susana Melendo, Pere Soler-Palacin, Silvia Simó, Victoria Fumadó, Miguel Lanaspa, M. Urretavizcaya, Mercedes Herranz, Marta Pareja, Fatima Ara, Santiago Cabañas, Rut del Valle, Ana Barrios, Enrique Otheo, José Luis Vázquez, Lola Falcón, Olaf Neth, Peter Olbrich, Walter Goicoechea, Laura Martín, Lucía Figueroa, María Llorente, María Penin, Claudia García, María García, Teresa Alvaredo, Ma Inmaculada Olmedo, Agustín López, Elvira Cobo, Mariam Tovizi, Pilar Galán, Sara Guillén, Adriana Navas, M. Luz García, Sara Pérez, María José Hernández, Arantxa Berzosa, Nerea Gallego, Ana López, Beatriz Ruiz, Santiago Alfayate, Ana Menasalvas, Eloísa Cervantes, María Méndez, Ángela Hurtado, Yolanda Ruiz, Cristina García, Inés Amich, Manuel Oltra, Álvaro Villaroya, Angustias Ocaña, Isabel Romero, María Fernanda Guzmán, M.J. Pascual, María Sánchez-Códez, Elena Montesinos, Julia Jensen, María Rodríguez, Gloria Caro, Neus Rius, Alba Gómez, Rafael Bretón, Margarita Rodríguez, Julio Romero, Ana Campos, Mercedes García, Rosa María Velasco, Zulema Lobato, Fernando Centeno, Elena Pérez, Paula Vidal, Corsino Rey, Ana Vivanco, Maruchi Alonso, Pedro Alcalá, Javier González de Dios, Eduard Solé, Laura Minguell, Itziar Astigarraga, Ma Ángeles Vázquez, Miguel Sánchez, Elena Díaz, Eduardo Consuegra, María Cabanillas, Luis Peña, Elisa Garrote, Maite Goicoechea, Irene Centelles, Santiago Lapeña, Sara Gutiérrez, Soraya Gutiérrez, Amparo Cavalle, José María Olmos, Alejandro Cobo, Sara Díaz, Beatriz Jiménez, Raúl González, Miguel Lafuente, Matilde Bustillo, Natividad Pons, Julia Morata, and Elsa Segura
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Male ,medicine.medical_specialty ,Adolescent ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Diagnostic accuracy ,Disease ,medicine.disease_cause ,Gastroenterology ,law.invention ,antigen test ,03 medical and health sciences ,0302 clinical medicine ,Antigen ,law ,030225 pediatrics ,Internal medicine ,Nasopharynx ,medicine ,Humans ,030212 general & internal medicine ,Pediatrics, Perinatology, and Child Health ,Child ,Antigens, Viral ,Pandemics ,Polymerase chain reaction ,Coronavirus ,business.industry ,Reverse Transcriptase Polymerase Chain Reaction ,SARS-CoV-2 ,Infant, Newborn ,COVID-19 ,Infant ,Reproducibility of Results ,Reverse transcriptase ,PCR ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,DNA, Viral ,Brief Reports ,Female ,business ,Pediatric population - Abstract
We conducted a multicenter clinical validity study of the Panbio coronavirus disease 2019 Antigen Rapid Test of nasopharyngeal samples in pediatric patients with coronavirus disease 2019-compatible symptoms of ≤5 days of evolution. Our study showed limited accuracy in nasopharyngeal antigen testing: overall sensitivity was 45.4%, and 99.8% of specificity, positive-predictive value was 92.5%.
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- 2020
4. Nutritional, clinical and immunological status of children at HIV diagnosis in the continental region of Equatorial Guinea
- Author
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David Aguilera-Alonso, Manuel Eyene Bacale Ayeto, Carlos Grasa, Policarpo Ncogo Ada, Adelina Endje Moliko, Pablo Rojo, Eloísa Cervantes Hernández, and Belen Garcia
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Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,030231 tropical medicine ,HIV diagnosis ,Nutritional Status ,HIV Infections ,Stage ii ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Immunological status ,Prevalence ,Medicine ,Humans ,Stage (cooking) ,Risk factor ,Child ,Immunodeficiency ,Retrospective Studies ,Anthropometry ,business.industry ,Public Health, Environmental and Occupational Health ,Infant, Newborn ,Infant ,medicine.disease ,Malnutrition ,Infectious Diseases ,Child, Preschool ,Equatorial Guinea ,Parasitology ,Female ,Underweight ,medicine.symptom ,business - Abstract
To evaluate the nutritional, clinical and immunological status of children at HIV diagnosis in the continental region of Equatorial Guinea.Children18 years diagnosed with HIV between 2009 and 2017 were included. Clinical, immunological and nutritional data were collected. Weight-for-height, weight-for-age and height-for-age Z-scores were calculated using WHO Child Growth Standards. The population was assessed in two equal periods (2009-2013 and 2014-2017) from the time of diagnosis.A total of 213 children were diagnosed with HIV (49.3% males), median age 3.8 years (IQR: 1.5-8.2). A total of 121 cases (56.8%) were at WHO clinical stage III, and 53 (24.9%) were at WHO clinical stage IV. CDC immunological stage II was diagnosed in 51/130 (39.2%) and CDC stage III in 44/130 (33.8%). About 56.2% of children were underweight (weight-for-age-2 SD); 20.1% moderately and 36.1% severely so. About 27.6% of children were wasted (weight-for-height-2 SD); 11.9% moderately and 15.7% severely so. About 56.3% of children were stunted (height-for-age-2 SD); 20.7% moderately and 35.6% severely so. The prevalence of wasting was higher in children ≤5 years than in children5 years (36.4% vs. 19.1%, P = 0.026). In the second period, the prevalence of moderate-severe immunodeficiency decreased (87.2% to 67.0%, P = 0.018), without significant differences in the other nutritional or clinical data. Severe underweight was a risk factor for moderate-severe immunodeficiency (aOR: 4 [95% CI: 1.4-11.4], P = 0.010).We highlight a high proportion of malnutrition at the time of HIV diagnosis in Guinea´s paediatric population. Early diagnosis of HIV infection is a priority, achievable by training Guinea´s physicians to suspect HIV early, introducing HIV molecular diagnostic techniques and ensuring intensive nutritional treatment.Evaluer le statut nutritionnel, clinique et immunologique des enfants au moment du diagnostic du VIH dans la région continentale de la Guinée équatoriale. MÉTHODES: Les enfants de moins de 18 ans diagnostiqués avec le VIH entre 2009 et 2017 ont été inclus. Les données cliniques, immunologiques et nutritionnelles ont été collectées. Les scores Z du poids pour la taille, du poids pour l'âge et de la taille pour l'âge ont été calculés en utilisant les normes de croissance de l'enfant de l'OMS. La population a été évaluée en deux périodes égales (2009-2013 et 2014-2017) à partir du moment du diagnostic. RÉSULTATS: 213 enfants ont été diagnostiqués avec le VIH (49,3% de sexe masculin), âge médian de 3,8 ans (IQR: 1,5-8,2). 121 cas (56,8%) étaient au stade clinique III de l’OMS et 53 (24,9%) étaient au stade clinique IV de l’OMS. Le stade immunologique II du CDC a été diagnostiqué chez 51/130 (39,2%) et le stade III du CDC chez 44/130 (33,8%). 56,2% des enfants avaient un poids insuffisant (poids pour âge-2 écart type [ET]); 20,1% modérément et 36,1% sévèrement. 27,6% des enfants étaient émaciés (poids pour taille-2 ET); 11,9% modérément et 15,7% sévèrement. 56,3% des enfants avaient un retard de croissance (taille pour l'âge-2 ET); 20,7% modérément et 35,6% sévèrement. La prévalence de l'émaciation était plus élevée chez les enfants ≤5 ans que chez les enfants5 ans (36,4% contre 19,1%; P = 0,026). Dans la deuxième période, la prévalence de l'immunodéficience modérée à sévère a diminué (87,2% à 67,0% ; P = 0,018), sans différences significatives dans les autres données nutritionnelles ou cliniques. L’insuffisance pondérale sévère était un facteur de risque d'immunodéficience modérée à sévère (aOR: 4 [IC95%: 1,4-11,4] ; P = 0,010).Nous mettons en évidence ici une forte proportion de malnutrition au moment du diagnostic du VIH dans la population pédiatrique guinéenne. Le diagnostic précoce de l'infection par le VIH est une priorité, réalisable en formant les médecins guinéens à identifier le VIH tôt, en introduisant des techniques de diagnostic moléculaire du VIH et en assurant un traitement nutritionnel intensif.
- Published
- 2019
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