1. Monitoring COVID-19 vaccine use in Italian long term care centers: The GeroCovid VAX study
- Author
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Angela Marie Abbatecola, Raffaele Antonelli Incalzi, Alba Malara, Annapina Palmieri, Anna Di Lonardo, Giorgio Fedele, Paola Stefanelli, Gilda Borselli, Marcello Russo, Marianna Noale, Stefano Fumagalli, Pietro Gareri, Enrico Mossello, Caterina Trevisan, Stefano Volpato, Fabio Monzani, Alessandra Coin, Giuseppe Bellelli, Chukwuma Okoye, Susanna Del Signore, Gianluca Zia, Elisa Bottoni, Carmine Cafariello, Graziano Onder, Abbatecola, A, Incalzi, R, Malara, A, Palmieri, A, Di Lonardo, A, Fedeli, G, Stefanelli, P, Borselli, G, Russo, M, Noale, M, Fumagalli, S, Gareri, P, Mossello, E, Trevisan, C, Volpato, S, Monzani, F, Coin, A, Bellelli, G, Okoye, C, Del Signore, S, Zia, G, Bottoni, E, Cafariello, C, and Onder, G more...
- Subjects
Aged, 80 and over ,COVID-19 Vaccines ,Frailty ,General Veterinary ,General Immunology and Microbiology ,SARS-CoV-2 ,Public Health, Environmental and Occupational Health ,COVID-19 ,COVID-19 vaccine ,Elderly ,Frailty syndrome ,GeroCovid Vax ,Long term care (LTC) ,Nursing homes (NH) ,Safety ,Aged ,Humans ,Long-Term Care ,Infectious Diseases ,80 and over ,Molecular Medicine - Abstract
The COVID-19 pandemic has changed routine care practice for older persons, especially in those with frailty living in long term care (LTC) facilities. Due to the high mortality rates of Nursing home (NH) residents during the first wave of the COVID-19 pandemic, priority for COVID-19 vaccinations was given to this vulnerable population. However, the safety and efficacy of such vaccines in older frail elders remains questionable due to the fact that initial randomized clinical trials (RCTs) for such vaccines did not include this population. This type of discrimination in patient participation in RCTs continues and has been recognized in the literature. Nevertheless, in the context of a worldwide emergency, COVID-19 vaccination in older persons living in LTC facilities may provide a solid basis to protect against negative outcomes, such as COVID-19 infection and death. In this report, we present the protocol of the GeroCovid Vax study, an Italian study that began in February 2021 which is aimed at investigating the safety and efficacy of the anti-SARS-CoV-2 vaccinations in older persons living in LTCs. This protocol specially aims to continuously and closely monitor events related to- and following- the anti-SARS-CoV-2 vaccination in elderly living in LTC facilities. In this report, we will provide information related to the study protocol and describe baseline characteristics of the sample. more...
- Published
- 2022
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