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3 results on '"Harrison Kamiru"'

1. Trends in Prevalence of Advanced HIV Disease at Antiretroviral Therapy Enrollment — 10 Countries, 2004–2015

Author

Adebobola Bashorun, Jonathan E. Kaplan, Yen Ngoc Le, Deborah Carpenter, Peter Preko, Beth A. Tippett Barr, Gideon Kwesigabo, Hank Tomlinson, Mahesh Swaminathan, Henry Debem, Fred Wabwire-Mangen, Joelle D eas Van Onacker, Solomon Odafe, Ermane G. Robin, Eduardo Samo Gudo, Nhan T Do, Modest Mulenga, Sheryl B. Lyss, Mayer Antoine, Shirish Balachandra, Chris Delcher, E. Kainne Dokubo, Alice Namale, Kwasi Torpey, Thomas J. Spira, Gram Mutandi, Eric van Praag, Elizabeth Gonese, Francisco Mbofana, Jean Wysler Domercant, Elliot Raizes, Carla Xavier, Sebastian Hachizovu, Timothy D Mastro, Mark Griswold, Helen Chun, Nirva Duval, Oseni Abiri, Christine Ross, Owen Mugurungi, George Bicego, Velephi Okello, Kesner Francois, Julie A. Denison, Isaac Zulu, Angela A Ramadhani, Duncan A. MacKellar, Robert Colebunders, Olivier Koole, Moses Bateganya, Kiren Mitruka, Harriet Nuwagaba-Biribonwoha, Simon Agolory, Kahemele Ng'wangu, Ramadhani Gongo, David W. Lowrance, Tedd V. Ellerbrock, Caroline Ryan, Charity Alfredo, Julius N Kalamya, Melissa Briggs, Carol Dukes Hamilton, Ikwo Oboho, Gracia Desforges, Spencer Lloyd, Ibrahim Dalhatu, Mohamed Mfaume, Sundeep Gupta, Dennis Onotu, Harrison Kamiru, Souleymane Sawadogo, Trista Bingham, Trong Ao, Varough M. Deyde, Bridget Mugisa, Andrew F. Auld, Yrvel Desir, Ndapewa Hamunime, Tsitsi Mutasa-Apollo, Naemi Shoopala, Andrew L. Baughman, Seymour G. Williams, Rituparna Pati, Michelle R. Adler, Aleny Couto, Nadjy Joseph, Valerie Pelletier, Alfredo Vergara, Jacob Dee, Ishani Pathmanathan, Ray W. Shiraishi, Peter Ehrenkranz, Abu S. Abdul-Quader, Patrick Swai, Stephanie Behel, Duc B. Nguyen, and Sharon Tsui

Subjects
medicine.medical_specialty, Health (social science), Epidemiology, Health, Toxicology and Mutagenesis, Art initiation, 030231 tropical medicine, MEDLINE, HIV Infections, Disease, Hiv testing, World health, 03 medical and health sciences, 0302 clinical medicine, Health Information Management, Advanced disease, Prevalence, Medicine, Humans, 030212 general & internal medicine, Full Report, business.industry, General Medicine, Antiretroviral therapy, Haiti, CD4 Lymphocyte Count, Anti-Retroviral Agents, Vietnam, Africa, Physical therapy, business, Demography, Hiv disease
Abstract

Monitoring prevalence of advanced human immunodeficiency virus (HIV) disease (i.e., CD4+ T-cell count

Published
2017

2. Decentralizing Access to Antiretroviral Therapy for Children Living with HIV in Swaziland

Author

Tedd V. Ellerbrock, Andrew F. Auld, Simon Agolory, Velephi Okello, George Bicego, Andrew L. Baughman, Harrison Kamiru, Peter Ehrenkranz, Charles Azih, Elaine J. Abrams, and Harriet Nuwagaba-Biribonwoha

Subjects
Microbiology (medical), Male, Pediatrics, medicine.medical_specialty, Referral, Adolescent, 030231 tropical medicine, Human immunodeficiency virus (HIV), Primary health care, HIV Infections, Standard score, medicine.disease_cause, Health Services Accessibility, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, 030212 general & internal medicine, Child, Retrospective Studies, business.industry, Hazard ratio, Infant, Newborn, Infant, Retrospective cohort study, Antiretroviral therapy, Confidence interval, Infectious Diseases, Treatment Outcome, Anti-Retroviral Agents, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, Lost to Follow-Up, business, Eswatini
Abstract

BACKGROUND In 2007, Swaziland initiated a hub-and-spoke model for decentralizing antiretroviral therapy (ART) access for HIV-infected children (

Published
2016

3. Implementation and Operational Research: Evaluation of Swaziland's Hub-and-Spoke Model for Decentralizing Access to Antiretroviral Therapy Services

Author

Ruben Sahabo, George Bicego, Velephi Okello, Harrison Kamiru, Andrew L. Baughman, Charles Azih, Peter Ehrenkranz, Andrew F. Auld, Harriet Nuwagaba-Biribonwoha, Simon Agolory, and Tedd V. Ellerbrock

Subjects
Gerontology, Adult, Male, Population, HIV Infections, Medication Adherence, Cohort Studies, Pregnancy, Antiretroviral Therapy, Highly Active, Case fatality rate, Medicine, Humans, Pharmacology (medical), Lost to follow-up, education, Retrospective Studies, education.field_of_study, business.industry, Mortality rate, Hazard ratio, Retrospective cohort study, Middle Aged, Confidence interval, Infectious Diseases, Anti-Retroviral Agents, Female, Lost to Follow-Up, Health Services Research, business, Delivery of Health Care, Eswatini, Cohort study, Demography
Abstract

BACKGROUND: In 2007 Swaziland initiated a hub-and-spoke model for decentralizing antiretroviral therapy (ART) access. Decentralization was facilitated through (1) down-referral of stable ART patients from overburdened central facilities (hubs) to primary health care clinics (spokes) and (2) ART initiation at spokes (spoke initiation). METHODS: We conducted a nationally representative retrospective cohort study among adult ART enrollees during 2004-2010 to assess the effect of down-referral and spoke-initiation on rates of loss to follow-up (LTFU) death and attrition (death or LTFU). Sixteen of 31 hubs were randomly selected using probability-proportional-to-size sampling. Seven selected facilities had initiated the hub-and-spoke model by study start. At these facilities 1149 of 24782 hub-initiated and maintained and 878 of 7722 down-referred or spoke-initiated patient records were randomly selected and analyzed. At the 9 hub-only facilities 483 of 6638 records were randomly selected and analyzed. Multivariable proportional hazards regression was used to assess effect of down-referral (a time-varying covariate) and spoke-initiation on outcomes. RESULTS: At ART initiation median age was 35 65% were female and median CD4 count was 147 cells per microliter. Controlling for known confounders down-referral was strongly protective against LTFU [adjusted hazard ratio (AHR) 0.38; 95% confidence interval (CI): 0.29 to 0.50] and attrition (AHR = 0.50; 95% CI: 0.34 to 0.76) but not mortality. Compared with hub-initiated and maintained patients spoke-initiated patients had lower LTFU (AHR 0.59; 95% CI: 0.45 to 0.77) and attrition rates (AHR 0.60; 95% CI: 0.47 to 0.77) but not mortality. CONCLUSIONS: Down-referral and spoke-initiation within a hub-and-spoke ART decentralization model were protective against LTFU and overall attrition and could facilitate future ART program expansion.

Published
2015

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