8 results on '"Ivan Sisa"'
Search Results
2. Effect of High Altitude on the Survival of COVID-19 Patients in Intensive Care Unit: A Cohort Study
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Manuel Jibaja, Estefania Roldan-Vasquez, Jordi Rello, Hua Shen, Nelson Maldonado, Michelle Grunauer, Ana María Díaz, Fernanda García, Vanessa Ramírez, Hernán Sánchez, José Luis Barberán, Juan Pablo Paredes, Mónica Cevallos, Francisco Montenegro, Soraya Puertas, Killen Briones, Marlon Martínez, Jorge Vélez-Páez, Mario Montalvo-Villagómez, Luis Herrera, Santiago Garrido, and Ivan Sisa
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Adult ,Male ,Altitude ,COVID-19 ,Middle Aged ,Critical Care and Intensive Care Medicine ,Respiration, Artificial ,Cohort Studies ,Intensive Care Units ,Humans ,Female ,Hospital Mortality ,Aged ,Retrospective Studies - Abstract
Purpose: The effect of high altitude ( ≥ 1500 m) and its potential association with mortality by COVID-19 remains controversial. We assessed the effect of high altitude on the survival/discharge of COVID-19 patients requiring intensive care unit (ICU) admission for mechanical ventilation compared to individuals treated at sea level. Methods: A retrospective cohort multi-center study of consecutive adults patients with a positive RT-PCR test for COVID-19 who were mechanically ventilated between March and November 2020. Data were collected from two sea-level hospitals and four high-altitude hospitals in Ecuador. The primary outcome was ICU and hospital survival/discharge. Survival analysis was conducted using semi-parametric Cox proportional hazards models. Results: Of the study population (n = 670), 35.2% were female with a mean age of 58.3 ± 12.6 years. On admission, high-altitude patients were more likely to be younger (57.2 vs. 60.5 years old), presented with less comorbidities such as hypertension (25.9% vs. 54.9% with p-value 3 sec (13.7% vs. 30.1%, p-value
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- 2022
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3. COVID-19 research in LMICs
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Marco Fornasini, Enrique Teran, and Ivan Sisa
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2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,SARS-CoV-2 ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Political science ,COVID-19 ,Humans ,General Medicine ,Developing Countries ,Virology - Published
- 2021
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4. A decade of Ecuador´s efforts to raise its health research output: a bibliometric analysis
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Pablo Burbano-Santos, Andrea Abad, Isaac Martinez-Cornejo, Ivan Sisa, and Isabel Espinosa
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Research Report ,Economic growth ,Bibliometric analysis ,Biomedical Research ,Higher education ,policy analysis ,Psychological intervention ,National health research system ,03 medical and health sciences ,0302 clinical medicine ,bibliometric analysis ,Political science ,Political movement ,Humans ,030212 general & internal medicine ,business.industry ,health research policy ,030503 health policy & services ,Health Policy ,Publications ,Public Health, Environmental and Occupational Health ,Policy analysis ,Variety (cybernetics) ,Cross-Sectional Studies ,Bibliometrics ,Original Article ,Ecuador ,Public aspects of medicine ,RA1-1270 ,0305 other medical science ,business ,Research Article - Abstract
Background: Over the past decade, the political movement called ‘Revolución Ciudadana’ implemented a variety of policies and interventions (P&I) in Ecuador to improve higher education and strengthen local research capacity. We refer specifically to the ‘Mandato 14’ and the Higher Education Law (LOES, Spanish acronym) launched in 2008 and 2010, respectively. Objective: To assess the impact of these P&I (Mandato 14/LOES) on the production of health sciences-related articles (HSRA), and the relationship of these HSRA with the country’s health priorities. Methods: A Scopus search was performed to retrieve HSRA published from 1999 to 2017. Bivariate analysis was used to assess variation between the period I (1999–2008) and period II (2009–2017). Further, we examined the association between the top 10 causes of mortality and the total HSRA output. Results: The final study sample consisted of 2784 articles. After 2008, Ecuadorian production of HSRA increased steadily from 671 to 2133 publications (p.05). Conclusions: Ecuadorian HSRA output increased significantly after 2008. This larger volume of scientific output could be the result to the Mandato 14/LOES implemented in the last decade. However, a low percentage of HSRA are dedicated to addressing the country’s health priorities. Proper planning, execution and monitoring of national health research agendas would reduce the mismatch between health burden and the HSRA output in Ecuador and other low-and middle-income countries.
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- 2020
5. Association between built environment and physical activity in Latin American countries: a multicentre cross-sectional study
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Rossina G Pareja, Mishell Barreno, Marianella Herrera-Cuenca, Ivan Sisa, Martha Cecilia Yépez García, Mónica Villar, Gervasio Gomez, Irina Kovalskys, Mauro Fisberg, Attilio Rigotti, Lilia Yadira Cortés, Hua Shen, and Viviana Guajardo
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Adult ,Population ,Psychological intervention ,Walking ,Residence Characteristics ,Environmental health ,Humans ,Medicine ,Built Environment ,Child ,education ,Exercise ,Neighbourhood (mathematics) ,Recreation ,Built environment ,education.field_of_study ,business.industry ,Questionnaire ,health policy ,General Medicine ,Physical activity level ,Cross-Sectional Studies ,Latin America ,Walkability ,epidemiology ,Environment Design ,Public Health ,business - Abstract
ObjectiveTo assess the association between the physical activity level and the built environment by accessibility, microinfrastructure and security in Latin America (LA).DesignWe conducted a multicentre cross-sectional study to collect physical activity and built environment data. The levels of physical activity were calculated through the International Physical Activity Questionnaire survey. Using the Neighbourhood Environment Walkability Scale-Abbreviated, characteristics of the built environment were measured through three domains: accessibility, microinfrastructure and security. To estimate the association of the built environment and physical activity, we used mixed effects logistic regression analysis. In addition, likelihood ratio test to account for clustered effect within countries and/or cities was used.SettingEight countries in LA.ParticipantsAdults aged 15–65 years (n=9218) living in urban areas and consented to participate of the Latin American Study of Nutrition and Health.ResultsMost of the population in LA had access to a grocery store (97.2%), public transport stop (91.5%) and children’s playground (81.6%). Metropolitan parks were more accessible in Ecuador (59.8%) and Colombia (59.2%) than in Venezuela (33.5%). Individuals located within 20 min of walking from sport facilities or children’s playground areas were more likely to perform moderate-to-high physical activity OR 1.20 (95% CI 1.06 to 1.36) and OR 1.25 (95% CI 1.02 to 1.53), respectively. Only 14.5% of the population from the region considered that their neighbourhood had an adequate design for walking or cycling. Likewise, among adults living in LA, only 39.75% had the perception of living in a safe neighbourhood.ConclusionsThis multicentre study shows that currently, LA built environment does not promote physical activity in the region. Our findings provide the rationale to push forward, at regional and national levels, policies and interventions that will help to achieve a safe, healthy and friendly built environment to encourage participation in active recreation and sports in leisure time.Trial registration numberNCT02226627.
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- 2021
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6. Rationale to continue approving placebo-controlled COVID-19 vaccine trials in LMICs
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Estefania Noblecilla, Ivan Sisa, and Fadya Orozco
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Therapeutic Equipoise ,2019-20 coronavirus outbreak ,medicine.medical_specialty ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,SARS-CoV-2 ,business.industry ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,MEDLINE ,COVID-19 ,General Medicine ,Placebo ,Supply & distribution ,Risk Assessment ,Placebos ,Correspondence ,medicine ,Humans ,Risk assessment ,Intensive care medicine ,business ,Developing Countries ,Randomized Controlled Trials as Topic - Published
- 2021
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7. Gender differences in cardiovascular risk assessment in elderly adults in Ecuador: evidence from a national survey
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Ivan Sisa
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Male ,Population ,Disease ,030204 cardiovascular system & hematology ,Risk Assessment ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Surveys and Questionnaires ,Medicine ,Humans ,030212 general & internal medicine ,Elderly adults ,education ,Aged ,education.field_of_study ,Sex Characteristics ,business.industry ,Mean age ,General Medicine ,Cardiovascular Diseases ,Coronary risk ,Population study ,Female ,Ecuador ,Risk assessment ,business ,Very high risk ,Demography - Abstract
The present study aimed to predict the risk of developing cardiovascular disease (CVD) over a 5-year period and how it might vary by sex in an ethnically diverse population of older adults. We used a novel CVD risk model built and validated in older adults named the Systematic Coronary Risk Evaluation in Older Persons (SCORE OP). A population-based study analyzed a total of 1307 older adults. Analyses were done by various risk categories and sex. Of the study population, 54% were female with a mean age of 75±7.1 years. According to the SCORE OP model, individuals were classified as having low (9.8%), moderate (48.1%), and high or very high risk (42.1%) of CVD-related mortality. Individuals at higher risk of CVD were more likely to be male compared with females, 53.9% vs 31.8%, respectively (p
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- 2018
8. Cardiovascular risk assessment in elderly adults using SCORE OP model in a Latin American population: The experience from Ecuador
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Ivan, Sisa
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Aged, 80 and over ,Male ,Age Factors ,Middle Aged ,Risk Assessment ,Decision Support Techniques ,Primary Prevention ,Cross-Sectional Studies ,Cardiovascular Diseases ,Risk Factors ,Health Status Indicators ,Humans ,Female ,Ecuador ,Aged - Abstract
Cardiovascular disease (CVD) mortality is predicted to increase in Latin America countries due to their rapidly aging population. However, there is very little information about CVD risk assessment as a primary preventive measure in this high-risk population.We predicted the national risk of developing CVD in Ecuadorian elderly population using the Systematic COronary Risk Evaluation in Older Persons (SCORE OP) High and Low models by risk categories/CVD risk region in 2009. Data on national cardiovascular risk factors were obtained from the Encuesta sobre Salud, Bienestar y Envejecimiento. We computed the predicted 5-year risk of CVD risk and compared the extent of agreement and reclassification in stratifying high-risk individuals between SCORE OP High and Low models. Analyses were done by risk categories, CVD risk region, and sex.In 2009, based on SCORE OP Low model almost 42% of elderly adults living in Ecuador were at high risk of suffering CVD over a 5-year period. The extent of agreement between SCORE OP High and Low risk prediction models was moderate (Cohen's kappa test of 0.5), 34% of individuals approximately were reclassified into different risk categories and a third of the population would benefit from a pharmacologic intervention to reduce the CVD risk.Forty-two percent of elderly Ecuadorians were at high risk of suffering CVD over a 5-year period, indicating an urgent need to tailor primary preventive measures for this vulnerable and high-risk population.
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- 2017
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