1. Effects of Gestational Sleep Patterns and Their Changes on Maternal Glycemia and Offspring Physical Growth in Early Life
- Author
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Jiaojiao Zou, Qian Wei, Peiqi Ye, Yuyang Shi, Yunhui Zhang, and Huijing Shi
- Subjects
Blood Glucose ,China ,Nutrition and Dietetics ,Overweight ,Body Mass Index ,Diabetes, Gestational ,gestational sleep patterns ,gestational diabetes mellitus (GDM) ,offspring physical growth ,cohort study ,Pregnancy ,Risk Factors ,Humans ,Female ,Obesity ,Sleep ,Food Science - Abstract
Maternal sleep patterns during pregnancy are drawing increased attention to examine its role in the regulation of maternal glycemia and physical growth of offspring within 24 months. Among 3329 eligible mother–child pairs included in the Shanghai Maternal–Child Pairs Cohort, sleep patterns of pregnant women were assessed by Pittsburgh Sleep Quality Index and objective measurement in early and late pregnancy. Offspring physical growth within 24 months was primarily indicated by the body mass index Z-score (BAZ), catch-up growth, and overweight/obesity. In total, 3329 and 382 pregnant women were included with subjectively assessed and objectively measured sleep pattern, respectively. The increased risk of GDM was associated with maternal night-time sleep duration ≥8.5 h in early pregnancy, or sleep quality change from poor to good during pregnancy (OR = 1.48; 95% CI, 1.06 to 2.07). In the GDM group, the effect of sleep duration in early pregnancy on overweight/obesity in offspring within 24 months showed a U-shaped curve, with a 1.73-fold and 1.43-fold increased risk of overweight/obesity of offspring in pregnant women with more...
- Published
- 2022