3 results on '"Joaquin Llacer"'
Search Results
2. Biodegradable Small-Scale Swimmers for Biomedical Applications
- Author
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Josep Puigmartí-Luis, Antón Rivas-Dapena, Bradley J. Nelson, Salvador Pané, Eva Pellicer, Joaquin Llacer-Wintle, and Xiang-Zhong Chen
- Subjects
Drug Carriers ,Materials science ,Light ,Mechanical Engineering ,Scale (chemistry) ,Hydrogels ,02 engineering and technology ,Robotics ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Nanostructures ,Biopolymers ,Pharmaceutical Preparations ,Mechanics of Materials ,Human–computer interaction ,Animals ,Humans ,General Materials Science ,0210 nano-technology ,Reactive Oxygen Species ,Clearance - Abstract
Most forms of biomatter are ephemeral, which means they transform or deteriorate after a certain time. From this perspective, implantable healthcare devices designed for temporary treatments should exhibit the ability to degrade and either blend in with healthy tissues, or be cleared from the body with minimal disruption after accomplishing their designated tasks. This topic is currently being investigated in the field of biomedical micro- and nanoswimmers. These tiny devices have the ability to move through fluids by converting physical or chemical energy into motion. Several architectures of these devices have been designed to mimic the motion strategies of nature's motile microorganisms and cells. Due to their motion abilities, these devices have been proposed as minimally invasive tools for precision healthcare applications. Hence, a natural progression in this field is to produce motile structures that can adopt, or even surpass, similar transient features as biological systems. The fate of small-scale swimmers after accomplishing their therapeutic mission is critical for the successful translation of small-scale swimmers' technologies into clinical applications. In this review, recent research efforts are summarized on the topic of biodegradable micro- and nanoswimmers for biomedical applications, with a focus on targeted therapeutic delivery., Advanced Materials, 33 (42), ISSN:0935-9648, ISSN:1521-4095
- Published
- 2021
3. COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management
- Author
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Sandro C. Esteves, Daniela Galliano, Luigi Carbone, Klaus Bühler, Manish Banker, Claus Yding Andersen, Robert Fischer, Evangelos G. Papanikolaou, Michael Grynberg, Fernando Neuspiller, Lan N. Vuong, Christophe Blockeel, Sesh Kamal Sunkara, Antonio La Marca, Panagiotis Drakopoulos, Alessandro Conforti, Pedro Xavier, Alberto Vaiarelli, Carlo Alviggi, Nikolaos P. Polyzos, Peter Humaidan, Filippo Maria Ubaldi, Ida Strina, Shu Foong, Joaquin Llacer, Matheus Roque, Michael H. Dahan, Raoul Orvieto, Hakan Yarali, Herman Tournaye, Marcos Horton, Fabiola C. Bento, Vriendenkring VUB, Faculty of Medicine and Pharmacy, Surgical clinical sciences, Centre for Reproductive Medicine - Gynaecology, Department of Embryology and Genetics, Biology of the Testis, Reproduction and Genetics, Alviggi, C., Esteves, S. C., Orvieto, R., Conforti, A., La Marca, A., Fischer, R., Andersen, C. Y., Buhler, K., Sunkara, S. K., Polyzos, N. P., Strina, I., Carbone, L., Bento, F. C., Galliano, D., Yarali, H., Vuong, L. N., Grynberg, M., Drakopoulos, P., Xavier, P., Llacer, J., Neuspiller, F., Horton, M., Roque, M., Papanikolaou, E., Banker, M., Dahan, M. H., Foong, S., Tournaye, H., Blockeel, C., Vaiarelli, A., Humaidan, P., and Ubaldi, F. M.
- Subjects
LOW PROGNOSIS PATIENTS ,medicine.medical_treatment ,Intracytoplasmic sperm injection ,Endocrinology ,Pregnancy ,In vitro fertilization ,Health care ,lcsh:Reproduction ,Poseidon criteria ,media_common ,Female infertility ,Reproductive Health Services/organization & administration ,Obstetrics and Gynecology ,Assisted reproductive technology ,COVID-19 ,Infertility ,Viewpoint ,Female ,Coronavirus Infections ,Infertility, Female ,Human ,reproductive medicine ,medicine.medical_specialty ,Infertility, Female/therapy ,lcsh:QH471-489 ,Reproductive Techniques, Assisted ,media_common.quotation_subject ,Reproductive Health Service ,Coronaviru ,Pneumonia, Viral ,Reproductive medicine ,Fertility ,Fertilization in Vitro ,lcsh:Gynecology and obstetrics ,Betacoronavirus ,medicine ,Humans ,Sperm Injections, Intracytoplasmic ,Pandemics ,lcsh:RG1-991 ,Betacoronaviru ,Pandemic ,business.industry ,Coronavirus Infection ,SARS-CoV-2 ,medicine.disease ,Coronavirus ,Family medicine ,Commentary ,Reproductive Health Services ,business ,Developmental Biology - Abstract
The prolonged lockdown of health services providing high-complexity fertility treatments –as currently recommended by many reproductive medicine entities– is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assisted reproductive technology (ART) treatments. By contrast, the total number of COVID-19 deaths reported so far represents approximately 1.0% of the total deaths expected to occur worldwide over the first three months of the current year. It seems, therefore, that the number of infants expected to be conceived and born –but who will not be so due to the lockdown of infertility services– might be as significant as the total number of deaths attributed to the COVID-19 pandemic. We herein propose remedies that include a prognostic-stratification of more vulnerable infertility cases in order to plan a progressive restart of worldwide fertility treatments. At a time when preventing complications and limiting burdens for national health systems represent relevant issues, our viewpoint might help competent authorities and health care providers to identify patients who should be prioritized for the continuation of fertility care in a safe environment.
- Published
- 2020
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