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16 results on '"Leufkens, Hubert G.M."'

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1. Impact of medicine shortages on patients - a framework and application in the Netherlands

2. Early Cost-Effectiveness of Onasemnogene Abeparvovec-xioi (Zolgensma) and Nusinersen (Spinraza) Treatment for Spinal Muscular Atrophy I in The Netherlands With Relapse Scenarios

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3. The impact of FDA and EMA regulatory decision-making process on the access to CFTR modulators for the treatment of cystic fibrosis

4. Market access to new anticancer medicines for children and adolescents with cancer in Europe

5. Estimation of manufacturing development costs of cell-based therapies: a feasibility study

6. Associations between uncertainties identified by the European Medicines Agency and national decision making on reimbursement by HTA agencies

7. Access to oxytocin and misoprostol for management of postpartum haemorrhage in Kenya, Uganda and Zambia: A cross-sectional assessment of availability, prices and affordability

8. Comprehensive evaluation of post-approval regulatory actions during the drug lifecycle–a focus on benefits and risks

9. Application of managed entry agreements for innovative therapies in different settings and combinations: A feasibility analysis

10. Decision making under uncertainty: comparing regulatory and health technology assessment reviews of medicines in the United States and Europe

11. Assessment of significant benefit for orphan medicinal products by European regulators may support subsequent relative effectiveness assessments by health technology assessment organizations

12. Selection of Blood, Blood Components, and Blood Products as Essential Medicines in 105 Low- and Middle-Income Countries

13. Key Considerations in the Health Technology Assessment of Advanced Therapy Medicinal Products in Scotland, The Netherlands, and England

14. Differences in Health Technology Assessment Recommendations Among European Jurisdictions: The Role of Practice Variations

15. Prescribing patterns and compliance with World Health Organization recommendations for the management of severe malaria: A modified cohort event monitoring study in public health facilities in Ghana and Uganda

16. Efficacy gap between phase II and subsequent phase III studies in oncology