1. Perceived Versus Objective Change in Walking Ability in Peripheral Artery Disease: Results from 3 Randomized Clinical Trials of Exercise Therapy
- Author
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McDermott, Mary M, Tian, Lu, Criqui, Michael H, Ferrucci, Luigi, Greenland, Philip, Guralnik, Jack M, Kibbe, Melina R, Li, Lingyu, Sufit, Robert, Zhao, Lihui, and Polonsky, Tamar S
- Subjects
Clinical Trials and Supportive Activities ,Rehabilitation ,Cardiovascular ,Prevention ,Clinical Research ,Aged ,Exercise Therapy ,Exercise Tolerance ,Female ,Humans ,Intermittent Claudication ,Male ,Middle Aged ,Patient Reported Outcome Measures ,Peripheral Arterial Disease ,Predictive Value of Tests ,Randomized Controlled Trials as Topic ,Recovery of Function ,Reproducibility of Results ,Time Factors ,Treatment Outcome ,Walk Test ,Walking ,exercise ,intermittent claudication ,patient-reported outcome measures ,peripheral artery disease ,patient‐reported outcome measures ,Cardiorespiratory Medicine and Haematology - Abstract
Background In people with lower-extremity peripheral artery disease, the effects of exercise on patient-reported outcomes remain unclear. Methods and Results Four hundred four people with peripheral artery disease in 3 clinical trials were randomized to exercise (N=205) or a control group (N=199) and completed the 6-minute walk and the Walking Impairment Questionnaire distance score (score 0-100, 100=best) at baseline and 6-month follow-up. Compared with the control group, exercise improved 6-minute walk distance by +39.8 m (95% CI, 26.8-52.8, P
- Published
- 2021