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A case of metastatic carcinoma ex pleomorphic adenoma (PA) of the submandibular gland is reported. While reports of local recurrence of this cancer are numerous, few cases of distant metastases have been reported. We report a case of a 52-year-old male patient with a history of PA diagnosed ten years previous. The patient presented reporting that the mass had increased size and pain during the previous six months. Needle biopsy results of this mass were compatible with a poorly differentiated carcinoma of the salivary ducts. Radical surgery with wide right neck dissection was performed with curative intent. Three years post-surgery liver and bony metastases were detected. In conclusion, the potential for malignant transformation of PA demands close follow-up of younger patients.

The purpose of this study was to investigate the presence of actinomyces in adenotonsillar disease, recurrent infections, or tonsillar hypertrophy in children. The study included 64 patients, ranging in age from 2 to 16 years, who had elective adenotonsillar surgery to treat either adenotonsillar hypertrophy (36 children) or recurrent adenotonsillitis (28 children). Adenotonsillar Actinomyces was present in 30 children (48%). No statistical significance was found between Actinomyces and recurrent adenotonsillitis or adenotonsillar hypertrophy. However, there was a statistically significant relationship identified between the presence of actinomycosis and age, with a greater occurrence of actinomycosis in children between 5 and 16 years old.

A 33 years-old female with a diagnosis of Kartagener's syndrome was studied. She had a clinical history of chronic sinusitis with nasal obstruction and rhinorrea, and a chronic cough with mucopurulent sputum. A paranasal sinus CT showed hypertrophyc mucosa. A thoracic CT showed a situs inversus and chronic bronchitis with bronchiectasis. The saccharin test lasted 55 minutes. The electron microscopy study showed in a a cross-sectional axoneme a total absence of the outer and inner arm of the 9th outer doublet in over a 100 cilias studied. No others ultrastructure anormalities were observed.

The paper deals about classical histologic and histochemical study for mucinoid substances through 7 laryngeal pieces coming from clinic autopsies. The gland units occurring in the two lower thirds of the epiglottis were formed by a great number of serous acini and mucinous tubuli, which secretion is acid and neutral mucous substances, as sialomucins, serving as lubricant and protective means. This glandular system convey through the epiglottic perforans holes, without break, the pre-epiglottic and epiglottic spaces, with the clinical repercussion that suggest the chance of encroachment for incipient epiglottic cancer to pre-epiglottic room.

In 10 patients (5 smokers) with benign laryngeal polyp of a single vocal cord, a biopsy was performed. Five normal control specimens were obtained from the larynx of recently deceased patients who underwent postmortem study. Langerhans cells were counted in specimens of histologically normal and pathological vocal cord mucosa after identification with S-100 polyclonal antibody. Langerhans cells were 11.5-fold more common in the epithelium of vocal cord polyps than in the mucosa of normal vocal cords.

A histochemistry study by means of lectins of vomeronasal organ or Jacobson's organ was performed in 5 Wistar rats. Vomeronasal organ is localized at the antero-inferior level of the septum and present two kinds of epithelium, an olfactory one and other respiratory, on the medial and on the lateral part, respectively. Olfactory epithelium shows a great reactivity to WGA lectin, moderate to PNA and weck to Con-A and SBA. In the respiratory epithelium the reactivity is moderate to DBA, PNa, SBA and WGA lectins for goblet cells, instead the periciliary sheat of mucus is reactive to all lectins but DBA and LTA.

A rare case of vascular leiomyoma of the inferior nasal turbinate in a diabetic patient is presented. Local excision was performed under endoscopic control. There have not been signs of recurrence after 2 years follow-up.

A case of acute bilateral vocal cord paralysis in adduction of an elderly woman with multisystem atrophy is reported. Emergency tracheotomy was performed.

Histochemical study done with lectins is useful in order to differentiate between several carbohydrates from glycoproteins and glycolipides present in cellular membranes. Plasma cells and eosinophils are very frequent findings in nose mucous of patients with nasal polyposis. Histochemistry with lectins of plasma cells show a reactivity of the cellular cytoplasma to ConA while the external cellular membrane stains with PNA.

Lymphoepithelial cysts of the parotid gland are frequently associated with HIV disease. We describe a case of a patient positive for HIV antibodies, stade A2, and extracapsular, bilateral and symmetric lymphoepithelial cysts of the parotid. The diagnosis was achieved by biopsy following a cervicotomy. A prior needle-biopsy procedure was disappointing. Literature review and discussion about the source and envolvement of those cysts linked to HIV-infection.

Kikuchi-Fujimoto disease (KF) is a new and uncommon malady of unknown etiology, first described in Japan. Clinically runs with neck adenopathies no larger than 2 cm diameter. Young women are more frequently affected. Main features are fever and nocturnal swelling in half of cases. Laboratory findings are not diagnostically helpful and positive diagnosis is only reliable upon ganglion's histology. Be unaware of this sickness can arise confusion with a malignant lymphoma. The illness is harmless and autolimited in a few months term. We report a new case of KF disease, diagnosed through excision biopsy, after a previous needle biopsy had awakened one's suspicion about a non Hodgkin lymphoma.

Necrotizing fasciitis is a rare but serious infection of subcutaneous tissue and deep fascia with resulting skin gangrene and septicaemia. Compute tomography (CT) seems to play a role in completing the clinical suspicion, especially in those case in which the disease does not manifest itself with subcutaneous crepitus or emphysema. Condition's causation reminded unknown and the microbial culture showed members of Streptococcus milleri genus.

Merkel cell carcinoma is an aggressive dermal neoplasm of neuroendocrine origin with a predilection for the head-and-neck region in elderly patients. We present a case of Merkel cell carcinoma of the nasal fossa. Local wide excision was performed.