1. Associations between apathy and comprehensive frailty as assessed by the Kihon Checklist among community‐dwelling Japanese older adults
- Author
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Michio Maruta, Suguru Shimokihara, Hyuma Makizako, Yuriko Ikeda, Gwanghee Han, Yoshihiko Akasaki, Yuma Hidaka, Taishiro Kamasaki, Takuro Kubozono, Mitsuru Ohishi, and Takayuki Tabira
- Subjects
Aged, 80 and over ,Male ,Frailty ,Frail Elderly ,Apathy ,Checklist ,Psychiatry and Mental health ,Cross-Sectional Studies ,Japan ,Activities of Daily Living ,Humans ,Female ,Independent Living ,Geriatrics and Gerontology ,Geriatric Assessment ,Gerontology ,Aged - Abstract
Frailty is a multidimensional condition characterised by reduced physical and psychological resilience. Older adults also frequently demonstrate apathy, suggesting that it shares similar neuro-physiological pathways with frailty. This cross-sectional study aimed to investigate the association between apathy and frailty as defined by a comprehensive assessment.We analyzed 882 older adults (mean age: 74.4 ± 6.4 years; 62.1% female) who participated in a community-based health check survey (Tarumizu Study). Apathy was measured by the Geriatric Depression Scale-3A, a three-item subset of the Geriatric Depression Scale-15, and frailty by the Kihon Checklist of physical, psychological, functional, and social status. Associations were examined by multinomial logistic regression with frailty status (robust, pre-frailty, frailty) as the dependent variable, apathy as the independent variable, and sociodemographic factors, medications, cognitive function, functional capacity, and mood symptoms as potential confounders.Apathy was observed in 23.7% of individuals, and logistic regression revealed significant associations with both pre-frailty and frailty after confounder adjustment (pre-frailty: odds ratio (OR) 1.80, 95% CI 1.22-2.64; frailty: OR 3.24, 95% CI 1.63-6.42). Participants with apathy also exhibited greater deficits in the Kihon Checklist subdomains instrumental activities of daily living (P = 0.022), physical function (P 0.001), oral function (P 0.001), and cognitive function (P = 0.001).Our findings underscore the importance of comprehensive frailty assessment and demonstrate that apathy can have pervasive deleterious effects on geriatric health.
- Published
- 2022
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