1. VÂSCOSUPLIMENTAREA ÎN BOALA ARTROZICĂ.
- Author
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Banciu, Mioara, Marian, Loredana, Banciu, C., and Tuduce, P.
- Subjects
- *
OSTEOARTHRITIS treatment , *HYALURONIC acid , *INJECTIONS , *MOLECULAR weights , *POLYSACCHARIDES , *SYNOVIAL fluid - Abstract
Viscosupplementation is a new therapy for the treatment of OA and refers to the i.a injection of hyaluronic acid (HA), a high molecular weight polysaccharide which is a major component of synovial fluid and cartilage, in order to relieve pain and improve function, In OA, the molecular weight and concentration of HA are diminished. The concept of viscosupplementation is based on the hypothesis that IA injections of HA could help restore the vis-coelasticity of the synovial fluid and promote the endogenous synthesis of a higer molecular weight and possibly more functional hyaluronan, thereby improving mobility and articular function, and reducing pain. Hyaluronan and its derivatives to have a structure modifying action by retarding structural progression in OA of the knee is considered. [ABSTRACT FROM AUTHOR]
- Published
- 2013