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Your search keyword '"Teirlinck, A. C."' showing total 6 results
Start Over Author "Teirlinck, A. C." Topic immunization
6 results on '"Teirlinck, A. C."'

1. Effectiveness of Immunization Products Against Medically Attended Respiratory Syncytial Virus Infection: Generic Protocol for a Test-Negative Case-Control Study.

Author

Roekel, Caren van, Poukka, Eero, Turunen, Topi, Nohynek, Hanna, Presser, Lance, Meijer, Adam, Heikkinen, Terho, Kramer, Rolf, Begier, Elizabeth, Teirlinck, Anne C, Knol, Mirjam J, and Investigators, PROMISE

Subjects
RESPIRATORY syncytial virus infections, HUMAN metapneumovirus infection, CASE-control method, RESPIRATORY infections, IMMUNIZATION, RESPIRATORY syncytial virus
Abstract

Monitoring the real-life effectiveness of respiratory syncytial virus (RSV) products is of major public health importance. This generic protocol for a test-negative design study aims to address currently envisioned approaches for RSV prevention (monoclonal antibodies and vaccines) to study effectiveness of these products among target groups: children, older adults, and pregnant women. The generic protocol approach was chosen to allow for flexibility in adapting the protocol to a specific setting. This protocol includes severe acute respiratory infection (SARI) and acute respiratory infection (ARI), both due to RSV, as end points. These end points can be applied to studies in hospitals, primarily targeting patients with more severe disease, but also to studies in general practitioner clinics targeting ARI. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

Author

Bijker, Else M., Bastiaens, Guido J. H., Teirlinck, Anne C., van Gemert, Geert-Jan, Graumans, Wouter, van de Vegte-Bolmer, Marga, Siebelink-Stoter, Rianne, Arens, Theo, Teelen, Karina, Nahrendorf, Wiebke, Remarque, Edmond J., Roeffen, Will, Jansens, Annemieke, Zimmerman, Dunja, Vos, Martijn, van Schaijk, Ben C. L., Wiersma, Jorien, van der Ven, André J. A. M., de Mast, Quirijn, van Lieshout, Lisette, Verweij, Jaco J., Hermsen, Cornelus C., Scholzen, Anja, and Sauerwein, Robert W.

Published
2013

5. Respiratory Syncytial Virus-Associated Hospital Admissions in Children Younger Than 5 Years in 7 European Countries Using Routinely Collected Datasets

Author

Reeves, Rachel M, van Wijhe, Maarten, Tong, Sabine, Lehtonen, Toni, Stona, Luca, Teirlinck, Anne C, Fernandez, Liliana Vazquez, Li, You, Giaquinto, Carlo, Fischer, Thea Kølsen, Demont, Clarisse, Heikkinen, Terho, Speltra, Irene, van Boven, Michiel, Bøås, Håkon, Campbell, Harry, Nair, Harish, Simonsen, Lone, Trebbien, Ramona, Bangert, Mathieu, Teirlinck, Anne, van der Hoek, Wim, van der Maas, Nicoline, Meijer, Adam, Bøas, Håkon, Bekkevold, Terese, Flem, Elmira, Cheret, Arnaud, Leach, Amanda, Stoszek, Sonia, Beutels, Philippe, Bont, Louis, Pollard, Andrew, Openshaw, Peter, Abram, Michael, Swanson, Kena, Rosen, Brian, and Molero, Eva

Subjects
Male, 0301 basic medicine, medicine.medical_specialty, Pediatrics, hospital admissions, respiratory syncytial virus, 030106 microbiology, Respiratory Syncytial Virus Infections, Europe, RSV, national registry data, Virus, 03 medical and health sciences, 0302 clinical medicine, Epidemiology, Humans, Immunology and Allergy, Medicine, 030212 general & internal medicine, Respiratory system, Respiratory Tract Infections, business.industry, Time trends, Vaccination, Infant, Newborn, Infant, Hospitals, 3. Good health, Pathogenic organism, Hospitalization, Infectious Diseases, medicine.anatomical_structure, Immunization, Child, Preschool, Respiratory Syncytial Virus, Human, Hospital admission, Female, business, Respiratory tract
Abstract

Background Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection (RTI) in young children. Registries provide opportunities to explore RSV epidemiology and burden. Methods We explored routinely collected hospital data on RSV in children aged < 5 years in 7 European countries. We compare RSV-associated admission rates, age, seasonality, and time trends between countries. Results We found similar age distributions of RSV-associated hospital admissions in each country, with the highest burden in children Conclusions Our results demonstrate the benefits and limitations of using linked routinely collected data to explore epidemiology and burden of RSV. Our future work will use these data to generate estimates of RSV burden using time-series modelling methodology, to inform policymaking and regulatory decisions regarding RSV immunization strategy and monitor the impact of future vaccines.

Published
2020
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6. Estimating Transmission Parameters for Respiratory Syncytial Virus and Predicting the Impact of Maternal and Pediatric Vaccination.

Author

Boven, Michiel van, Teirlinck, Anne C, Meijer, Adam, Hooiveld, Mariëtte, Dorp, Christiaan H van, Reeves, Rachel M, Campbell, Harry, van der Hoek, Wim, Investigators, RESCEU, van Boven, Michiel, van Dorp, Christiaan H, and RESCEU Investigators

Subjects
*RESPIRATORY syncytial virus, *BASIC reproduction number, *VACCINATION, *OLDER people, *RESPIRATORY infections, *RESEARCH, *VIRAL vaccines, *IMMUNIZATION, *RESEARCH methodology, *DISEASE incidence, *MEDICAL cooperation, *EVALUATION research, *COMPARATIVE studies, *HOSPITAL care, *IMMUNITY, *RESEARCH funding, *RESPIRATORY syncytial virus infections, *INFECTIOUS disease transmission
Abstract

Background: Respiratory syncytial virus (RSV) is a leading cause of respiratory tract illness in young children and a major cause of hospital admissions globally.Methods: Here we fit age-structured transmission models with immunity propagation to data from the Netherlands (2012-2017). Data included nationwide hospitalizations with confirmed RSV, general practitioner (GP) data on attendance for care from acute respiratory infection, and virological testing of acute respiratory infections at the GP. The transmission models, equipped with key parameter estimates, were used to predict the impact of maternal and pediatric vaccination.Results: Estimates of the basic reproduction number were generally high (R0 > 10 in scenarios with high statistical support), while susceptibility was estimated to be low in nonelderly adults (<10% in persons 20-64 years) and was higher in older adults (≥65 years). Scenario analyses predicted that maternal vaccination reduces the incidence of infection in vulnerable infants (<1 year) and shifts the age of first infection from infants to young children.Conclusions: Pediatric vaccination is expected to reduce the incidence of infection in infants and young children (0-5 years), slightly increase incidence in 5 to 9-year-old children, and have minor indirect benefits. [ABSTRACT FROM AUTHOR]

Published
2020
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