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Purpose: To report a rare case of isolated lumbar vertebral body infarction following lumbar artery embolization for suspected retroperitoneal haemorrhage., Methods: We present the case of a 75-year-old male who underwent lumbar artery embolization due to a suspected retroperitoneal haemorrhage post-surgery. Magnetic resonance imaging (MRI) was performed to monitor post-embolization severe lumbar pain., Results: Initial MRI two days post-embolization showed no osseous signal changes or epidural abscess. A subsequent MRI 26 days post-embolization was performed because of increasing lumbar back pain and it revealed a new bone infarction at the L3 vertebral body. CT showed embolization deposits within the vertebral body, not present before the procedure., Conclusion: This unique case underscores the importance of considering vertebral body infarction as a potential complication following lumbar artery embolization. MRI was critical in early detection of the bone infarction, while CT confirmed the presence of embolization material. Awareness of this rare complication is crucial for prompt diagnosis and management., Competing Interests: Statements and Declarations. The authors did not receive support from any organization for the submitted work. The authors have no relevant financial or non-financial interests to disclose. All authors attest that they meet the current International Committee of Medical Journals Editors (ICMJE) criteria for authorship. The authors declare that the work described has been performed in accordance with the Declaration of Helsinki of the World Medical Association. The local ethics committee of the Medical University Graz approved this case report (EK Nr. 1022/2024). A written informed consent was obtained from the patient to participate in this study and publication of its results. The authors declare that this report does not contain any personal information that could lead to the identification of the patient. Disclosure: During the preparation of this work, the authors used ChatGPT4 (OpenAI) in order to refine language. After using this tool, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)