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In this paper, we present a novel communication channel, called the absorption channel, inspired by information transmission in neurons. Our motivation comes from in-vivo nano-machines, emerging medical applications, and brain-machine interfaces that communicate over the nervous system. Another motivation comes from viewing our model as a specific deletion channel, which may provide a new perspective and ideas to study the general deletion channel. For any given finite alphabet, we give codes that can correct absorption errors. For the binary alphabet, the problem is relatively trivial and we can apply binary (multiple-) deletion correcting codes. For single-absorption error, we prove that the Varshamov-Tenengolts codes can provide a near-optimal code in our setting. When the alphabet size $q$ is at least $3$, we first construct a single-absorption correcting code whose redundancy is at most $3\log_q(n)+O(1)$. Then, based on this code and ideas introduced in \cite{Gabrys2022IT}, we give a second construction of single-absorption correcting codes with redundancy $\log_q(n)+12\log_q\log_q(n)+O(1)$, which is optimal up to an $O\left(\log_q\log_q(n)\right)$. Finally, we apply the syndrome compression technique with pre-coding to obtain a subcode of the single-absorption correcting code. This subcode can combat multiple-absorption errors and has low redundancy. For each setup, efficient encoders and decoders are provided.

We first give a construction of binary $t_1$-deletion-$t_2$-insertion-burst correcting codes with redundancy at most $\log(n)+(t_1-t_2-1)\log\log(n)+O(1)$, where $t_1\ge 2t_2$. Then we give an improved construction of binary codes capable of correcting a burst of $4$ non-consecutive deletions, whose redundancy is reduced from $7\log(n)+2\log\log(n)+O(1)$ to $4\log(n)+6\log\log(n)+O(1)$. Lastly, by connecting non-binary $b$-burst-deletion correcting codes with binary $2b$-deletion-$b$-insertion-burst correcting codes, we give a new construction of non-binary $b$-burst-deletion correcting codes with redundancy at most $\log(n)+(b-1)\log\log(n)+O(1)$. This construction is different from previous results., Comment: Results are covered by others' work

In the recent years, DNA has emerged as a potentially viable storage technology. DNA synthesis, which refers to the task of writing the data into DNA, is perhaps the most costly part of existing storage systems. Accordingly, this high cost and low throughput limits the practical use in available DNA synthesis technologies. It has been found that the homopolymer run (i.e., the repetition of the same nucleotide) is a major factor affecting the synthesis and sequencing errors. Quite recently, [26] studied the role of batch optimization in reducing the cost of large scale DNA synthesis, for a given pool $\mathcal{S}$ of random quaternary strings of fixed length. Among other things, it was shown that the asymptotic cost savings of batch optimization are significantly greater when the strings in $\mathcal{S}$ contain repeats of the same character (homopolymer run of length one), as compared to the case where strings are unconstrained. Following the lead of [26], in this paper, we take a step forward towards the theoretical understanding of DNA synthesis, and study the homopolymer run of length $k\geq1$. Specifically, we are given a set of DNA strands $\mathcal{S}$, randomly drawn from a natural Markovian distribution modeling a general homopolymer run length constraint, that we wish to synthesize. For this problem, we prove that for any $k\geq 1$, the optimal reference strand, minimizing the cost of DNA synthesis is, perhaps surprisingly, the periodic sequence $\overline{\mathsf{ACGT}}$. It turns out that tackling the homopolymer constraint of length $k\geq2$ is a challenging problem; our main technical contribution is the representation of the DNA synthesis process as a certain constrained system, for which string techniques can be applied., Comment: 21 pages

Motivated by applications in polymer-based data storage, we study the problem of reconstructing a string from part of its composition multiset. We give a full description of the structure of the strings that cannot be uniquely reconstructed (up to reversal) from their multiset of all of their prefix-suffix compositions. Leveraging this description, we prove that for all $n\ge 6$, there exists a string of length $n$ that cannot be uniquely reconstructed up to reversal. Moreover, for all $n\ge 6$, we explicitly construct the set consisting of all length $n$ strings that can be uniquely reconstructed up to reversal. As a by product, we obtain that any binary string can be constructed using Dyck strings and Catalan-Bertrand strings. For any given string $\bm{s}$, we provide a method to explicitly construct the set of all strings with the same prefix-suffix composition multiset as $\bm{s}$, as well as a formula for the size of this set. As an application, we construct a composition code of maximal size. Furthermore, we construct two classes of composition codes which can respectively correct composition missing errors and mass reducing substitution errors. In addition, we raise two new problems: reconstructing a string from its composition multiset when at most a constant number of substring compositions are lost; reconstructing a string when only given its compositions of substrings of length at most $r$. For each of these setups, we give suitable codes under some conditions., Comment: 25 pages; errors corrected

We study random string-duplication systems, which we call P��lya string models. These are motivated by DNA storage in living organisms, and certain random mutation processes that affect their genome. Unlike previous works that study the combinatorial capacity of string-duplication systems, or various string statistics, this work provides exact capacity or bounds on it, for several probabilistic models. In particular, we study the capacity of noisy string-duplication systems, including the tandem-duplication, end-duplication, and interspersed-duplication systems. Interesting connections are drawn between some systems and the signature of random permutations, as well as to the beta distribution common in population genetics.

When transmitting information over a noisy channel, two approaches, dating back to Shannon's work, are common: assuming the channel errors are independent of the transmitted content and devising an error-correcting code, or assuming the errors are data dependent and devising a constrained-coding scheme that eliminates all offending data patterns. In this paper we analyze a middle road, which we call a semiconstrained system. In such a system, which is an extension of the channel with cost constraints model, we do not eliminate the error-causing sequences entirely, but rather restrict the frequency in which they appear. We address several key issues in this study. The first is proving closed-form bounds on the capacity which allow us to bound the asymptotics of the capacity. In particular, we bound the rate at which the capacity of the semiconstrained $(0,k)$-RLL tends to $1$ as $k$ grows. The second key issue is devising efficient encoding and decoding procedures that asymptotically achieve capacity with vanishing error. Finally, we consider delicate issues involving the continuity of the capacity and a relaxation of the definition of semiconstrained systems.

The Ising channel, which was introduced in 1990, is a channel with memory that models Inter-Symbol interference. In this paper we consider the Ising channel with feedback and find the capacity of the channel together with a capacity-achieving coding scheme. To calculate the channel capacity, an equivalent dynamic programming (DP) problem is formulated and solved. Using the DP solution, we establish that the feedback capacity is the expression $C=(\frac{2H_b(a)}{3+a})\approx 0.575522$ where $a$ is a particular root of a fourth-degree polynomial and $H_b(x)$ denotes the binary entropy function. Simultaneously, $a=\arg \max_{0\leq x \leq 1} (\frac{2H_b(x)}{3+x})$. Finally, a simple, error-free, capacity-achieving coding scheme is provided together with outlining a strong connection between the DP results and the coding scheme.