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Your search keyword '"Mottola, F. F."' showing total 3 results
Start Over Author "Mottola, F. F." Topic intensive care medicine
3 results on '"Mottola, F. F."'

1. Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?

Author

Mottola F. F., Verde N., Ricciolino R., Di Mauro M., Migliaccio M. G., Carfora V., Spiniello G., Coppola N., Macera M., Calo F., Sagnelli C., Monari C., Martini S., Stornaiuolo G., Stanzione M., De Pascalis S., Cascone A., Bianco A., Gentile V., Camaioni C., De Angelis G., Marino G., Astorri R., Starace M., Minichini C., Di Fraia A., De Sio I., Niosi M., Borrelli S., Celia B., Ceparano M., Cirillo S., De Luca M., Mazzeo G., Paoli G., Russo M. G., Russo A., Mottola, F. F., Verde, N., Ricciolino, R., Di Mauro, M., Migliaccio, M. G., Carfora, V., Spiniello, G., Coppola, N., Macera, M., Calo, F., Sagnelli, C., Monari, C., Martini, S., Stornaiuolo, G., Stanzione, M., De Pascalis, S., Cascone, A., Bianco, A., Gentile, V., Camaioni, C., De Angelis, G., Marino, G., Astorri, R., Starace, M., Minichini, C., Di Fraia, A., De Sio, I., Niosi, M., Borrelli, S., Celia, B., Ceparano, M., Cirillo, S., De Luca, M., Mazzeo, G., Paoli, G., Russo, M. G., and Russo, A.

Subjects
medicine.medical_specialty, Myocarditis, heart failure, Review, Disease, 030204 cardiovascular system & hematology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Pericarditis, 0302 clinical medicine, Diabetes mellitus, Pandemic, medicine, myocardial injury, 030212 general & internal medicine, lcsh:Science, Intensive care medicine, Ecology, Evolution, Behavior and Systematics, business.industry, Mechanism (biology), SARS-CoV-2 infection, Paleontology, Cancer, medicine.disease, Space and Planetary Science, Heart failure, cardiovascular system, lcsh:Q, business
Abstract

As of January 2020, a new pandemic has spread from Wuhan and caused thousands of deaths worldwide. Several studies have observed a relationship between coronavirus disease (COVID-19) infection and the cardiovascular system with the appearance of myocardial damage, myocarditis, pericarditis, heart failure and various arrhythmic manifestations, as well as an increase in thromboembolic risk. Cardiovascular manifestations have been highlighted especially in older and more fragile patients and in those with multiple cardiovascular risk factors such as cancer, diabetes, obesity and hypertension. In this review, we will examine the cardiac involvement associated with SARS-CoV-2 infection, focusing on the pathophysiological mechanism underlying manifestations and their clinical implication, taking into account the main scientific papers published to date.

Published
2020
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2. Anticoagulant treatment in COVID-19: a narrative review

Author

Carfora, Vincenzo, Spiniello, Giorgio, Ricciolino, Riccardo, Di Mauro, Marco, Migliaccio, Marco Giuseppe, Mottola, Filiberto Fausto, Verde, Nicoletta, Coppola, Nicola, Sagnelli, Caterina, De Pascalis, Stefania, Stanzione, Maria, Stornaiuolo, Gianfranca, Cascone, Angela, Martini, Salvatore, Macera, Margherita, Monari, Caterina, Calò, Federica, Bianco, Andrea, Russo, Antonio, Gentile, Valeria, Camaioni, Clarissa, De Angelis, Giulia, Marino, Giulia, Astorri, Roberta, De Sio, Ilario, Niosi, Marco, Borrelli, Serena, Celia, Benito, Ceparano, Maria, Cirillo, Salvatore, De Luca, Maria, Mazzeo, Grazia, Paoli, Giorgio, Russo, Maria Giovanna, Carfora, V., Spiniello, G., Ricciolino, R., Di Mauro, M., Migliaccio, M. G., Mottola, F. F., Verde, N., Coppola, N., Sagnelli, C., De Pascalis, S., Stanzione, M., Stornaiuolo, G., Cascone, A., Martini, S., Macera, M., Monari, C., Calo, F., Bianco, A., Gentile, V., Camaioni, C., De Angelis, G., Marino, G., Astorri, R., De Sio, I., Niosi, M., Borrelli, S., Celia, B., Ceparano, M., Cirillo, S., De Luca, M., Mazzeo, G., Paoli, G., Russo, M. G., and Russo, A.

Subjects
medicine.medical_specialty, Disease, 030204 cardiovascular system & hematology, medicine.disease_cause, Article, Pathogenesis, 03 medical and health sciences, Anticoagulation, 0302 clinical medicine, Internal medicine, Pandemic, medicine, Humans, Thrombophilia, Endothelial dysfunction, Intensive care medicine, 030304 developmental biology, Coronavirus, 0303 health sciences, Hematology, business.industry, SARS-CoV-2, Anticoagulants, COVID-19, Thrombosis, medicine.disease, COVID-19 Drug Treatment, Host-Pathogen Interactions, business, Cytokine storm, Cardiology and Cardiovascular Medicine, Algorithms
Abstract

The actual Coronavirus Disease (COVID 19) pandemic is due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the coronavirus family. Besides the respiratory involvement, COVID 19 patients frequently develop a pro-coagulative state caused by virus-induced endothelial dysfunction, cytokine storm and complement cascade hyperactivation. It is common to observe diffuse microvascular thrombi in multiple organs, mostly in pulmonary microvessels. Thrombotic risk seems to be directly related to disease severity and worsens patients’ prognosis. Therefore, the correct understanding of the mechanisms underlying COVID-19 induced prothrombotic state can lead to a thorough assessment of the possible management strategies. Hence, we review the pathogenesis and therapy of COVID 19-related thrombosis disease, focusing on the available evidence on the possible treatment strategies and proposing an algorithm for the anticoagulation strategy based on disease severity.

Published
2020
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3. Acute kidney injury in COVID-19: a case-report

Author

Nicoletta Verde, Nicola Coppola, Marco Giuseppe Migliaccio, Riccardo Ricciolino, Giorgio Spiniello, Filiberto Fausto Mottola, Vincenzo Carfora, Marco Di Mauro, Di Mauro, M., Migliaccio, M. G., Ricciolino, R., Spiniello, G., Carfora, V., Verde, N., Mottola, F. F., and Coppola, N.

Subjects
Nephrology, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Urology, Pneumonia, Viral, MEDLINE, Clinical Laboratory Technique, Text mining, COVID-19 Testing, Internal medicine, Medicine, Intensive care medicine, Lung, Aged, 80 and over, Kidney Function Test, Betacoronaviru, Clinical Deterioration, Pandemic, business.industry, SARS-CoV-2, Coronavirus Infection, Acute kidney injury, Oxygen Inhalation Therapy, COVID-19, Acute Kidney Injury, medicine.disease, Patient Care Management, Nephrology - Letter to the Editor, Treatment Outcome, Female, business, Tomography, X-Ray Computed, Human
Published
2020

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