1. Association between physical exercise and stroke recurrence among first-ever ischemic stroke survivors.
- Author
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Hou L, Li M, Wang J, Li Y, Zheng Q, Zhang L, Yao Q, Zhang J, Dong S, Zhou M, and Zhu C
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Cerebral Infarction physiopathology, Female, Humans, Male, Middle Aged, Recurrence, Risk Factors, Survival Analysis, Survivors, Young Adult, Brain Ischemia physiopathology, Exercise physiology, Ischemic Stroke physiopathology
- Abstract
The relationship between exercise and stroke recurrence is controversial. This study was designed to test whether an association exists between exercise and ischemic stroke recurrence in first-ever ischemic stroke survivors. Data were collected from January 2010 to June 2016. Baseline information was obtained during face-to-face interviews, and follow-up phone interviews were conducted every 3 months. Exercise type, frequency, intensity, and duration were recorded. Discrete-time survival analysis was used to determine the relationship between exercise and stroke recurrence. 760 first-ever ischemic stroke survivors who were able to exercise were enrolled. After adjusting for covariates, patients who exercised 3.5-7 h per week and more than 7 h per week had a lower relapse risk than patients who did not exercise (3.5-7: OR 0.415; > 7: OR 0.356). Moreover, if the fluctuation of exercise duration was over 4 h, the patients had a higher risk of stroke recurrence than those with variability of less than 2 h (OR 2.153, P = 0.013). Stroke survivors who engage in long-term regular mild exercise (more than 5 sessions per week and lasting on average 40 min per session) have a lower recurrence rate. Irregular exercise increases the risk of stroke recurrence.
- Published
- 2021
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