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2. Gabriel Andral e L'Italia Influenze reciproche tra il padre della moderna ematologia e il "Bel Paese".

Author

Giuliani, Rita, Bruzzese, Sofia, and Borghi, Luca

Abstract

Gabriel Andral (1797-1876) was one of the most emblematic exponent of the French medical revolution of the 19th century and the undisputed father of modern hematology. He spent most of his adolescence in Italy because his father, Guillaume Andral, was a military doctor who became the personal physician of Murat in Naples. Although he lived in Italy just for a few years before going back to France and graduating in Paris, he indeed kept in touch with our Country and strongly affected Italian medicine. As a matter of fact, many of his works were translated into Italian and he soon became well known in the peninsula, playing an important role in the next Italian medical progress. [ABSTRACT FROM AUTHOR]

Published
2022
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3. Implementation of the ERAS (Enhanced Recovery After Surgery) protocol for colorectal cancer surgery in the Piemonte Region with an Audit and Feedback approach: study protocol for a stepped wedge cluster randomised trial: a study of the EASY-NET project

Author

Pagano, E, Pellegrino, L, Rinaldi, F, Palazzo, V, Donati, D, Meineri, M, Palmisano, S, Rolfo, M, Bachini, I, Bertetto, O, Borghi, F, Ciccone, G, ERAS Colon-Rectum Piemonte study group members. ERAS Colon-Rectum Piemonte study group members: Site investigators: Federica Borromeo, Fabio Priora, Sergio Gentilli, Luca Portigliotti, Paolo Massucco, Marco Palisi, Felice Borghi, Luca Pellegrino, Maurizio De Giuli, Aridai Resendiz, Paola Bellomo, Silvia Marola, IRCCS Candiolo Alfredo Mellano, Dario Ribero, Roberto, Polastri, Andrea Muratore, Nicoletta Sveva Pipitone, Garino, Mauro, Ospedale Cardinal Massaia, Asti: Elisabetta Castagna, Pozzo, Gabriele, Ospedale Castelli, Verbania: Andrea Caneparo, Adriana Ginardi, Reggina Lagana, Monica Carrera, Stefania Muzio, Ospedale, Civile, Ivrea: Luca Panier Suffat, Ivan, Lettini, Alberto Kiss, Valentina Gentile, Roberto Saracco, Donatella Scaglione, Andrea Gattolin, Roberto Rimonda, Francesco Battafarano, Luigi Oragano, Luca Lorenzin, Carlo Palenzona, Carmine Gianfranco Di Somma, Eliana Giaminardi, Marco Calgaro, Marco Naddeo, Piero Cumbo, Emma Marchigiano, Francesca, Cravero, Amisano, Marco Francesco, Francesco, Lemut, Tiziana Viora, Luciano Bonaccorsi, Silvio Testa, Clemente De Rosa, Marco, Brunetti, Matteo, Gatti, Carlo Bima, Enrico Gibin, Quaglino, Francesco, Festa, Federico, Luca, Bonatti, Morino, Mario, Allaix, Marco Ettore, Paolo De Paolis, Ida Marina Raciti, Mauro, Santarelli, Gitana, Scozzari, Felice, Borghi, Donati, Danilo, Maurizio, Meineri, Palmisano, Sarah, Pellegrino, Luca, Ciccone, Giovannino, Rosalba, Galletti, Pagano, Eva, Sandrucci, Sergio, Ilaria, Bachini, Anna De Magistris, Barbara, Mitola, Paolo, Massucco, Alessio, Rizzo, Caironi, Pietro, Monica, Rolfo, Anna, Orlando, Bertetto, Oscar, Francesco, Brunetti, Corinna, Defilè, DIAS MARTINS, VITOR HUGO, Lisa, Giacometti, Papurello, Matteo, Fabio, Saccona, and Danila, Turco.

Subjects
medicine.medical_specialty, audit, Audit, Disease cluster, quality in health care, Feedback, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Medicine, Humans, Multicenter Studies as Topic, Duration (project management), Enhanced recovery after surgery, Pandemics, Randomized Controlled Trials as Topic, Protocol (science), business.industry, SARS-CoV-2, Incidence (epidemiology), COVID-19, General Medicine, Length of Stay, Colorectal surgery, Italy, Sample size determination, 030220 oncology & carcinogenesis, Emergency medicine, 030211 gastroenterology & hepatology, Surgery, colorectal surgery, business, Colorectal Neoplasms, Enhanced Recovery After Surgery
Abstract

IntroductionThe ERAS protocol (Enhanced Recovery After Surgery) is a multimodal pathway aimed to reduce surgical stress and to allow a rapid postoperative recovery. Application of the ERAS protocol to colorectal cancer surgery has been limited to a minority of hospitals in Italy. To promote the systematic adoption of ERAS in the entire regional hospital network in Piemonte an Audit and Feedback approach (A&F) has been adopted together with a cluster randomised trial to estimate the true impact of the protocol on a large, unselected population.MethodsA multicentre stepped wedge cluster randomised trial is designed for comparison between standard perioperative management and the management according to the ERAS protocol. The primary outcome is the length of hospital stay (LOS). Secondary outcomes are: incidence of postoperative complications, time to patients’ recovery, control of pain and patients’ satisfaction. With an A&F approach the adherence to the ERAS items is monitored through a dedicated area in the study web site. The study includes 28 surgical centres, stratified by activity volume and randomly divided into four groups. Each group is randomly assigned to a different activation period of the ERAS protocol. There are four activation periods, one every 3 months. However, the planned calendar and the total duration of the study have been extended by 6 months due to the COVID-19 pandemic.The expected sample size of about 2200 patients has a high statistical power (98%) to detect a reduction of LOS of 1 day and to estimate clinically meaningful changes in the other endpoints.Ethics and disseminationThe study protocol has been approved by the Ethical Committee of the coordinating centre and by all participating centres. Study results will be timely circulated within the hospital network and published in peer-reviewed journals.Trial registration numberNCT04037787.

Published
2021

4. CERCANDO GUIDA E LUME DAI SUONI E DAI RUMORI. SULLA PRIMA DIFFUSIONE DELLO STETOSCOPIO IN ITALIA (CA. 1820-1830) LUCA BORGHI.

Author

BORGHI, LUCA

Subjects
*STETHOSCOPES, *UNIVERSITIES & colleges, *MEDICAL research, *MEDICAL care, *CHEST diseases
Abstract

News o f the invention o f the stethoscope by Laennec in 1816 and o f positive reception o f this instrument by French medicài community reached Italy very soon, even before the publication o f the first edition o f the Traite de l'Auscultation médiate ( 1819). But initial curiosity and enthusiasm aroused by the new medical tool in many Italian universities, rapidly faded away, probably due to the lack o f expert guides and o f the patience needed by the initial training in mediated auscultation. In the mid-1820s, while old physicians and professors put aside the wooden chest-explorer as useless, a new generation o f young physicians - some o f them still in their medical studies - gave a new start to the Italian interest for Laennec's tube and, also by means o f technical ameliorations o f the instrument, contributed to definitively set the stethoscope as an essential aid for diagnosis o f chest diseases in our Country'. [ABSTRACT FROM AUTHOR]

Published
2018

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