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Your search keyword '"Kheiraoui, F"' showing total 3 results
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3 results on '"Kheiraoui, F"'

2. Quality of life among healthcare workers: A multicentre cross-sectional study in Italy.

Author

Kheiraoui, F., Gualano, M. R., Mannocci, A., Boccia, A., and La Torre, G.

Subjects
*MEDICAL personnel, *QUALITY of life, *MULTIPLE regression analysis, *MULTIVARIATE analysis, *STANDARD deviations
Abstract

Objective: To evaluate the quality of life among doctors, nurses, and occupational safety and health technologists (OSHT). Study design: Cross-sectional study was undertaken in a population of healthcare workers in 10 Italian regions. Methods: The Italian version of Short Form-36 (SF-36) was anonymously and voluntarily self-administered by participants to assess the perceived health-related quality of life (HRQOL). The HRQOL scores for the sample and the Italian population were compared. A multiple linear regression was performed to assess the influence of age, gender, role, socializing time, working time, years spent in healthcare and years spent in the specific department on the SF-36 score. Results: The sample included 324 healthcare workers [57.1% women, mean age 39.0 (standard deviation 10.2) years]: 52.6% were medical doctors, 36.8% were nurses and 10.5% were OSHTs. Workers with a career of >15 years achieved a general health score lower than that of workers with a shorter career, while those who spent more time in socializing activities achieved a higher mental health score. The multivariate analysis showed that increasing age is positively related to role emotional levels (β = 0.243; P = 0.002), while it appears to be inversely related to general health (β = -0.218; P = 0.007) and physical function (β = -0.246; P = 0.001). Nurses had lower scores for bodily pain (β = -0.214; P < 0.001), social function (β = -0.242; P = 0.001) and role emotional (β = -0.211; P = 0.006) compared with doctors. Compared with the general Italian population, healthcare workers had higher scores for general health, physical function, role physical, bodily pain and mental health, and lower scores for vitality, social function and role emotional. Conclusions: Healthcare workers have different levels of HRQOL related to their professional role. In particular, nurses have lower quality of life. These results may help to identify the main roles and attitudes that could cause frustration, dissatisfaction and emotional stress in healthcare workers. [ABSTRACT FROM AUTHOR]

Published
2012
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3. Cost-effectiveness analysis of oral fentanyl formulations for breakthrough cancer pain treatment

Author

Lucia Sara D'Angiolella, Renato Vellucci, Lorenzo G. Mantovani, Giancarlo Cesana, Giuseppe Casale, Massimo Allegri, Carlo Favaretti, Flavia Kheiraoui, Paolo Cortesi, Cortesi, P, D'Angiolella, L, Vellucci, R, Allegri, M, Casale, G, Favaretti, C, Kheiraoui, F, Cesana, G, and Mantovani, L

Subjects
Critical Care and Emergency Medicine, Economics, Cost-Benefit Analysis, Cancer Treatment, lcsh:Medicine, Administration, Oral, Social Sciences, Fentanyl, 0302 clinical medicine, Quality of life, Health care, Medicine and Health Sciences, Ethnicities, 030212 general & internal medicine, lcsh:Science, Analgesics, education.field_of_study, Multidisciplinary, Morphine, Cost–benefit analysis, Drugs, Cancer Pain, Cost-effectiveness analysis, Italian People, Analgesics, Opioid, Italy, Oncology, Anesthesia, Quality-Adjusted Life Years, Research Article, medicine.drug, medicine.medical_specialty, Cost-Effectiveness Analysis, Population, Administration, Sublingual, 03 medical and health sciences, Health Economics, medicine, Humans, Pain Management, medicine (all), education, Intensive care medicine, Pharmacology, business.industry, lcsh:R, Breakthrough Pain, Models, Theoretical, Economic Analysis, Quality-adjusted life year, Health Care, Opioids, Economic Impact Analysis, People and Places, Quality of Life, lcsh:Q, Population Groupings, business, Cancer pain, 030217 neurology & neurosurgery
Abstract

Breakthrough cancer Pain (BTcP) has a high prevalence in cancer population. Patients with BTcP reported relevant health care costs and poor quality of life. The study assessed the cost-effectiveness of the available Oral Fentanyl Formulations (OFFs) for BTcP in Italy. A decision-analytical model was developed to estimate costs and benefits associated with treatments, from the Italian NHS perspective. Expected reductions in pain intensity per BTcP episodes were translated into, percentage of BTcP reduction, resource use and Quality-Adjusted-Life-Years (QALYs). Relative efficacy, resources used and unit costs data were derived from the literature and validated by clinical experts. Probabilistic and deterministic sensitivity analyses were performed. At base-case analysis, Sublingual Fentanyl Citrate (FCSL) compared to other oral formulations reported a lower patient's cost (€1,960.8) and a higher efficacy (18.7% of BTcP avoided and 0.0507 QALYs gained). The sensitivity analyses confirmed the main results in all tested scenarios, with the highest impact reported by BTcP duration and health care resources consumption parameters. Between OFFs, FCSL is the cost-effective option due to faster reduction of pain intensity. However, new research is needed to better understand the economic and epidemiologic impact of BTcP, and to collect more robust data on economic and quality of life impact of the different fentanyl formulations. Different fentanyl formulations are available to manage BTcP in cancer population. The study is the first that assesses the different impact in terms of cost and effectiveness of OFFs, providing new information to better allocate the resources available to treat BTcP and highlighting the need of better data.

Published
2017

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