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Clinical course of acute nonspecific lymphadenitis of the face and neck is studied in 241 patients aged 1-14 years in order to improve the diagnosis and therapy of this condition. General clinical examinations were supplemented by laser biophotometry and assessment of the activities of some local defense factors (lysozyme, beta-lysine, secretory and serum IgA). Multiple-modality treatment for the first time included magnetic laser therapy (MLT), and its efficacy is assessed. Results of biophotometry helped define objective criteria for the diagnosis and evaluation of treatment efficacy in children with acute lymphadenitis of the face and neck. MLT proved to be a highly effective treatment modality, decreasing the inflammation and correcting local (oral) defense factors. Use of MLT accelerated all phases of the inflammatory process, promoted its regression at the serous stage, and decreased the incidence of suppurative forms of acute lymphadenitis by 40%.

A total of 102 patients with mandibular fractures were treated by multiple-modality treatment including infrared (IR) laser exposure and magnetic and laser therapy (MT). For monitoring the treatment efficacy and predicting its results, nonspecific defense factors and intensity of free-radical oxidation (FRO) in the saliva were assessed. IR laser and MT by the Uleĭ-2K device stimulated local defense factors, decreased the intensity of salivary FRO, and thus promoted the healing of mandibular fractures.

In rabbits isolated CO2 and He-Ne laser irradiation promotes early granulation of wounds and accelerates epithelialization with more complete restitution of the regenerated skin organ specificity. The best effect was achieved when combined laser irradiation was applied. This was further corroborated by the immunohistochemical investigation.