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AIM:To observe the clinical efficacy of phacoemulsification combined with goniosynechialysis for chronic angle-closure glaucoma with cataract. METHODS:Fifty eyes in 50 patients with chronic angle-closure glaucoma and cataract, but without complications underwent phacoemulsification and intraocular lens(IOL)implantation, combined with goniosynechialysis. All patients were followed up for 3mo. The best corrected visual acuity(BCVA), intraocular pressure(IOP), anterior chamber depth and angle were recorded and compared between pre-operation and post-operation. The results were showed by means plus or subtracting deviation standard. The BCVA, IOP, anterior chamber depth and angle were analysed by t test. RESULTS:The best corrected visual acuity at 3mo after operations was significantly higher than that before operations(t=8.76, P=0.001). The IOP at 3mo after operations was 15.63±3.11mmHg and was significantly lower than that(45.12±5.30mmHg)before operations(t=6.27, P=0.000). The anterior chamber depth at 3mo after operations was 3.57±0.02mm, and was significantly deeper than that(1.43±0.25mm)before operations(t=8.16, P=0.001). Compared with preoperative anterior chamber angle, those after operations were wider(Z=-4.432,P=0.000; Z=-2.432,P=0.016; Z=-4.379,P=0.000; Z=-4.538,P=0.000).CONCLUSION:Phacoemulsification combined with goniosynechialysis is safe and effective for chronic angle-closure glaucoma with cataract, which can control IOP and improve the visual acuity.

AIM: To study the characteristics and variability of flash electroretinogram(F-ERG)in normal adults of different age stages.METHODS: Thirty cases(60 eyes)of healthy physical examinaees were divided into two groups according to age: 20～30 years old group(15 cases, 30 eyes )and 40～50 years old group(15 cases, 30 eyes), F-ERG was recorded according to standard of International Society for Clinical Electrophysiology of Vision(ISCEV), and the parameters and coefficient of variation in the two groups were compared.RESULTS: Compared with 20～30 years old age group, the implicit time was extended and the amplitude decreased in the 40～50 years old age group, especially amplitude of the dark adaptation of 3.0, light adaptation of 3.0 and oscillatory potentials showed statistical significance(PCONCLUSION: Compared with 20～30 years old age group, the implicit time of ERG is extended and the amplitude is decreased in the 40～50 years old age group. The coefficient of variation of implicit time is the minimum.

AIM: To accurately measure the implicit time and amplitude of a-, b-wave from flash electroretinogram(ERG)through filtering technology, eliminate oscillatory potentials interference. METHODS: Full-field ERGs were recorded in 30 eyes of 15 physical check-ups, measured the implicit time and amplitude of a-, b-wave, when the passband was set at 0.6～300Hz and 0.6～70Hz, and correlation was performed among those results by paired t-test.RESULTS: When the passband was set at 0.6～70Hz, a-, b-wave had a single peak, compared with the passband was set at 0.6～300Hz, the implicit time of a-, b-wave was prolonged, amplitude was decreased(PCONCLUSION: A passband of 0.6～70Hz was the best choice to obtain smooth a- and b-waves from the original ERG, It could accurately measure the implicit time and amplitude of a-, b-wave.