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Start Over Author "Pertici, Francesca" Topic lectins
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2. Optimizing Divalent Inhibitors of Pseudomonas aeruginosa Lectin LecA by Using A Rigid Spacer.

Author

Pertici, Francesca, de Mol, Nico J., Kemmink, Johan, and Pieters, Roland J.

Subjects
PSEUDOMONAS aeruginosa, LECTINS, GLUCOSE, TRIAZOLES, CALORIMETRY
Abstract

Rigid spacers: Optimal highly potent divalent ligands of the P. aeruginosa lectin LecA have been prepared. The ligands consist of a rigid spacer derived from glucose–triazole units (see figure). Systematic variation of the number of spacer units and the aglycon linker led to a 7500‐fold enhancement in potency. [ABSTRACT FROM AUTHOR]

Published
2013
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