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(1) Background: The study examined the reliability (test–retest, intra- and inter-day) and validity of a portable 3D scanning method when quantifying human leg volume. (2) Methods: Fifteen males volunteered to participate (age, 24.6 ± 2.0 years; stature, 178.9 ± 4.5 cm; body mass, 77.4 ± 6.5 kg; mean ± standard deviation). The volume of the lower and upper legs was examined using a water displacement method (the criterion) and two consecutive 3D scans. Measurements were taken at baseline, 1 h post-baseline (intra-day) and 24 h post-baseline (inter-day). Reliability and validity of the 3D scanning method was assessed using Bland–Altman limits of agreement and Pearson's product moment correlations. (3) Results: With respect to the test–retest reliability, the 3D scanning method had smaller systematic bias and narrower limits of agreement (±1%, and 3–5%, respectively) compared to the water displacement method (1–2% and 4–7%, respectively), when measuring lower and upper leg volume in humans. The correlation coefficients for all reliability comparisons (test–retest, intra-day, inter-day) would all be regarded as 'very strong' (all 0.94 or greater). (4) Conclusions: The study's results suggest that a 3D scanning method is a reliable and valid method to quantify leg volume. [ABSTRACT FROM AUTHOR]

Background Leg volume (LV) is an important reference in nutrition, physiology in exercise, or clinical diagnosis. Therefore, how to evaluate LV easily and quickly with accuracy is important in these areas. Aim To develop a simple anthropometric estimation formula with ease of use and good accuracy for leg volume (LV) of female labourers. Subjects One hundred and thirty female labourers (110 subjects for formula regression procedure and 20 subjects for the comparison phase) were recruited as subjects with no reported leg surgery history, trauma, or deformity. Methods A set of 3 D scanners was used to measure the range data of each subject’s leg. Results The resultant LV estimation formula is LV = 0.215 × LL × CTH1.620 with R2 = 0.967, in which LL stands for leg length and CTH for circumference of thigh. Mean error of this LV estimation is 0.10% and much smaller than that of the previous study (25.11% with significant difference). Conclusion An anthropometric estimation formula for female labourers’ leg volume was developed in this study. Estimation mean error of this formula is much smaller than the one in the previous study. This formula is easy to use and shows good accuracy in estimating female labourers’ leg volume.

Leg volume (LV) is an important reference in nutrition, physiology in exercise, or clinical diagnosis. Therefore, how to evaluate LV easily and quickly with accuracy is important in these areas. To develop a simple anthropometric estimation formula with ease of use and good accuracy for leg volume (LV) of female labourers. One hundred and thirty female labourers (110 subjects for formula regression procedure and 20 subjects for the comparison phase) were recruited as subjects with no reported leg surgery history, trauma, or deformity. A set of 3 D scanners was used to measure the range data of each subject's leg. The resultant LV estimation formula is LV = 0.215 × LL × CTH1.620 with R2 = 0.967, in which LL stands for leg length and CTH for circumference of thigh. Mean error of this LV estimation is 0.10% and much smaller than that of the previous study (25.11% with significant difference). An anthropometric estimation formula for female labourers' leg volume was developed in this study. Estimation mean error of this formula is much smaller than the one in the previous study. This formula is easy to use and shows good accuracy in estimating female labourers' leg volume. [ABSTRACT FROM AUTHOR]

Background: Recent advances in technology have allowed intermittent pneumatic compression (IPC) devices to develop so that their function mimics the process and principles of manual lymphatic drainage (MLD); however, research into the effectiveness of such devices is lacking. This study aimed to investigate the effectiveness of a patented IPC technique designed to mimic MLD (the LymphAssist), compared with a typical sequential IPC regimen. Methods and Results: Forty patients with a confirmed diagnosis of lower limb ISL (International Society of Lymphology) stage II or III lymphedema were recruited into this three-phased study. A bilateral leg volume assessment and quality-of-life assessment were completed at four clinic visits across the course of the study. The LymphAssist IPC regimen was significantly more effective in reducing distal leg volume than the sequential mode (mean volume reduction: 230 ± 135 mL vs. 140 ± 84 mL, respectively, p = 0.01). Improvements in leg volume were transient as both groups demonstrated a rebound or increase in volume during the washout period (LymphAssist: 238 ± 168 mL, sequential: 276 ± 158 mL, p = 0.3). Overall, IPC was effective in improving quality-of-life scores (mean reduction: 10 ± 11, p < 0.001). Conclusion: IPC is effective in reducing limb volume and improving quality of life for patients with lower limb lymphedema. IPC that mimics the MLD process has been shown to be more effective in reducing leg volume compared with traditional sequential IPC in the distal aspect of the leg. The increase in leg volume observed after discontinuation of IPC suggests that regular treatment is required to maintain its associated effects. Clinical Trial Registration Number: NTC 03856281. [ABSTRACT FROM AUTHOR]

Abstract Background Lymphoedema is a chronic condition that causes swelling in the body tissues. Presently, there is no cure for lymphoedema; instead, current treatment is aimed at lifelong management to help control symptoms. Intermittent pneumatic compression (IPC) therapy can be considered as an adjunct to standard lymphoedema care; however, research regarding the efficacy of this treatment modality is limited. Methods Twenty participants were recruited from an outpatient lymphoedema clinic (South Wales, UK) to a feasibility randomised control trial designed to evaluate the efficacy of an IPC device (LymphAssist, Huntleigh Healthcare) in reducing lower limb volume. The primary objective was to assess feasibility in terms of (1) study feasibility, including recruitment, retention and assessment of outcome measures, and (2) intervention feasibility, including intervention fidelity and acceptability to participants. Participants were randomly assigned to a control group (n = 10) or intervention group (n = 10). The control group received their standard lymphoedema care only for a 6-month period, whereas the intervention group received their standard lymphoedema care plus an IPC device to use for 6 months. A bilateral lower limb assessment and quality of life survey were undertaken at baseline and 3- and 6-month time points. Results The study recruited to target within the planned time frame with a retention rate of 80%. Issues relating to potential recruitment bias and study attrition were identified and possible solutions explored. In addition, supplementary primary outcome measures that are important to the study population were identified and will be incorporated into the design of future studies. Conclusion This feasibility study identified that a larger randomised controlled trial investigating the efficacy of home use IPC devices is feasible with modifications to the study protocol. Trial registration This trial is registered with clinicaltrials.gov (NCT03825263).

Background: Prolonged wheelchair sitting is known to lead to venous stasis and results in leg edema.Objective: To clarify how a dynamic cushion affects leg edema in people with spinal cord injuries (SCI) evoked by wheelchair sitting, we measured the changes in leg volume induced during wheelchair sitting with a dynamic air cushion or a static cushion.Methods: Seven wheelchair users with SCI participated in this study. Leg edema during wheelchair sitting was evaluated with strain gauge plethysmography (the gauge was placed 10 cm proximally from the medial malleolus). Following a period of rest, the subjects sat on a reclining wheelchair containing a dynamic cushion for 15 min. Then, the protocol was repeated with a static cushion. The above two procedures were performed in a random order. These data were statistically compared between the two procedures.Results: The change in leg volume observed during sitting on the dynamic cushion (-0.02 ± 0.21 ml/100 ml) was smaller than that observed during sitting on the static cushion (0.18 ± 0.28 ml/100 ml) (P< 0.05).Conclusions: These results suggested that the dynamic air cushion relieved leg edema induced by wheelchair sitting in individuals with SCI. [ABSTRACT FROM AUTHOR]

Background: Graduated compression stocking (GCS) use during flights demonstrated to positively impact leg oedema. Nevertheless, these data were collected in a single flight, mainly at the ankle, and using greater than 20 mmHg GCS. This investigation reports data from 16 flights in which the same passenger's leg circumferences variation were assessed wearing non-graduated ankle-sock or a below-knee 15–20 mmHg GCS. Methods: The limb was divided by the circumferences in eight sectors, every 4 cm, labelled from 1 to 8, starting from the ankle up. The assessment was done at the take-off and after a 4-h flight time, for a total of 16 flights. The subject used non-graduated ankle socks (elastic band at 4 cm from B-point) during the outgoing flight and below-knee GCS (15–20 mmHg) during the return flight. Interface pressure was assessed at the ankle point of minimum girth (B) and ascending proximally every 4 cm (B+cm) for the GCS, and at B and at the elastic band level (B + 4 cm) for the sock. Results: GCS interface pressure was 13.3 ± 2.5 mmHg in B and 18.1 ± 2.4 mmHg in B + 4 cm. The sock interface pressure was 3.1 ± 0.7 mmHg in B and 8.1 ± 0.9 mmHg at the band level (B + 4 cm). Socks led to a significant total volume increase (117.3 ± 25.8 mL; 5.2% ±1.1%; P < 0.0001). GCS led to a non-significant total volume decrease (–3.1 ± 14.4 mL; –0.1 ± 0.6%; P = 0.3964) and did not allow for volume increase. The different sectors showed a heterogeneous volume variation, not following a precisely graduated or progressive compression profile. Conclusions: Leg oedema following a 4-h flight is controlled by <20 mmHg GCS. Leg fluids, with and without GCS, are mobilized in a non-graduated profile from the ankle to the knee after prolonged sitting on a plane. [ABSTRACT FROM AUTHOR]

This study aimed to evaluate the accuracy of the leg volume obtained by the Microsoft Kinect sensor to predict the composition of light lamb carcasses. The trial was performed on carcasses of twenty-two male lambs (17.6 ± 1.8 kg, body weight). The carcasses were split into eight cuts, divided into three groups according to their commercial value: high-value, medium value, and low-value group. Linear, area, and volume of leg measurements were obtained to predict carcass and cuts composition. The leg volume was acquired by two different methodologies: 3D image reconstruction using a Microsoft Kinect sensor and Archimedes principle. The correlation between these two leg measurements was significant (r = 0.815, p < 0.01). The models to predict cuts and carcass traits that include leg Kinect 3D sensor volume are very good in predicting the weight of the medium value and leg cuts (R2 of 0.763 and 0.829, respectively). Furthermore, the model, which includes the Kinect leg volume, explained 85% of its variation for the carcass muscle. The results of this study confirm the good ability to estimate cuts and carcass traits of light lamb carcasses with leg volume obtained with the Kinect 3D sensor.

Our aim was to test the effects of Andullation therapy on pain threshold, pain perception, feeling of well-being, arterial pressure, and leg volume in healthy and unhealthy patients. We used a multidirectional vibration (frequency range: 5–40 Hz; peak-to-peak amplitude: 2–8 mm; acceleration: 0.4–2 m/s2) in an undulatory way through the surface of the body when the patient was in contact with a mattress (“andullation”). The vibes traveled from the heel to the head in a random fashion while the participants (N = 50) were lying on the mattress. We measured the pain threshold using an algometer; pain perception and well-being through a visual analog scale (VAS); arterial pressure with an electronic sphygmomanometer; and leg volume with Kuhnke’s technique. Measurements were made just before the first andullation session and after the fifth andullation session. Every participant received andullation sessions of 30 min a day for 5 consecutive days. The patients’ pain threshold significantly (P < .001) increased by 34.48% and 25.79% in the lumbar and trapezius zones, respectively, after 5 sessions of therapy. The subjective perception of pain decreased by 52.3% and the feeling of well-being increased by 45.1%. The systolic and diastolic pressures significantly (P < .001) decreased by 6.44 and 4.68 mm Hg on average, respectively. Leg volume significantly decreased (P < .01) by 64.39 mL after the fifth andullation session. Despite not including a control group in our study, the andullation intervention showed an improvement in pain, well-being, arterial pressure, and lower limb volume in the studied population. [ABSTRACT FROM AUTHOR]

BACKGROUND: Below knee two-component compression stockings (AD) have revealed as effective for compression treatment of venous leg ulcers. Upto groin, thigh length stocking (AG) may enhance clinical effects, however wear comfort of these stocking may be affected. OBJECTIVE: venous haemodynamic in relation to the length of compression stockings. METHODS: A two-component AD stocking (37 mmHg) and two thigh length stockings (AG 37, with an interface pressure of 37 mmHg; AG 45, with an interface pressure of 45 mmHg) were tested by 16 patients with CVI. Leg volume changes and venous ejection fraction and venous filling index were measured, whilst quality of life and wear comfort were surveyed by questionnaires. RESULTS: Volume of both the lower limb and the thigh was reduced by AG stockings, whereas AD stockings reduced only the volume of the lower limb and increased thigh volume. Venous hemodynamic, ejection fraction and filling index were improved by AG and AD stockings, AG, however, was superior to AD. Quality of life and comfort of the stockings was assessed as good for AG 37 mmHg, AG 45 mmHg and AD 37 mmHg. CONCLUSIONS: Thigh length two component stockings (AG) were shown to be superior to below knee stocking (AD) with regard to volume reduction and venous hemodynamic, yet wear comfort was not impaired. These results imply that healing of trophic skin changes e.g. ulcers will be faster when thigh length two component stocking will be worn. [ABSTRACT FROM AUTHOR]

Objective To show the superiority of 500 mg calcium dobesilate vs. placebo in reduction of edema of the lower limbs in patients with chronic venous insufficiency, Clinical, Etiological, Anatomical and Pathophysiological classes C3/C4. Methods A total of 351 patients were randomized (n = 174 calcium dobesilate, n = 177 placebo). Active treatment was 500 mg calcium dobesilate, three times daily for 12 weeks, with a 12-week follow-up. Results At the end of treatment, the relative volume change in the most pathological leg was −0.6 ± 4.8% with calcium dobesilate compared to −0.3 ± 3.3% with placebo (p = 0.09). At the end of follow-up, this was −1.01 ± 5.4% for calcium dobesilate vs. −0.08 ± 3.5% for placebo (p = 0.002). Conclusions Calcium dobesilate treatment resulted in no significant volume change in the most pathological leg between baseline and end of treatment. However, the calcium dobesilate group showed a significantly greater volume decrease in the most pathological leg at the end of follow-up. Calcium dobesilate was well-tolerated, with a safety profile consistent with previously published data. [ABSTRACT FROM AUTHOR]

Purpose: The present study was an attempt to investigate the effect of unstable footwear on lower leg muscle activity, volume change and subjective discomfort during prolonged standing.Methods: Ten healthy subjects were recruited to stand for 2 h in three footwear conditions: barefoot, flat-bottomed shoe and unstable shoe. During standing, lower leg discomfort and EMG activity of medial gastrocnemius (MG) and tibialis anterior (TA) muscles were continuously monitored. Changes in lower leg volume over standing time also were measured.Results: Lower leg discomfort rating reduced significantly while subjects standing on unstable shoe compared to the flat-bottomed shoe and barefoot condition. For lower leg volume, less changes also were observed with unstable shoe. The activity level and variation of right MG muscle was greater with unstable shoe compared to the other footwear conditions; however regarding the left MG muscle, significant difference was found between unstable shoe and flat-bottomed shoe only for activity level. Furthermore no significant differences were observed for the activity level and variation of TA muscles (right/left) among all footwear conditions.Conclusions: The findings suggested that prolonged standing with unstable footwear produces changes in lower leg muscles activity and leads to less volume changes. Perceived discomfort also was lower for this type of footwear and this might mean that unstable footwear can be used as ergonomic solution for employees whose work requires prolonged standing. [ABSTRACT FROM AUTHOR]

Objective/Background The objective of this study was to compare the efficacy and comfort of inelastic bandages (IBs) and adjustable Velcro ® compression devices (AVCDs) in reducing venous leg edema in the initial treatment phase. Methods Forty legs from 36 patients with untreated venous edema (C3EpsAsdPr) were randomized to two groups. Patients in the first group received IBs ( n = 20) and those in the second AVCDs ( n = 20). Both compression devices were left on the leg day and night, and were renewed after 1 day. Patients in the AVCD group were asked to re-adjust the device as needed when it felt loose. Leg volume was calculated using the truncated cone formula at baseline (T0), after 1 day (T1) and after 7 days (T7). The interface pressure of the two compression devices was measured by an air filled probe, and the static stiffness index calculated after applying compression at T0 and T1, and just before removal of compression on T1 and T7. Patient comfort with regard to the two compression systems was assessed by grading signs and symptoms using a visual analog scale. Results At T1, the median percent volume reduction was 13% for the IB group versus 19% for the AVCD group; at T7 it was 19% versus 26%, respectively ( p < .001). The pressure of the IBs was significantly higher compared with the AVCDs at T0 (63 vs. 43 mmHg) but dropped by > 50% over time, while it remained unchanged with AVCDs owing to the periodic readjustment by the patient. Comfort was reported to be similar with the two compression devices. Conclusion Re-adjustable AVCDs with a resting pressure of around 40 mmHg are more effective in reducing chronic venous edema than IBs with a resting pressure of around 60 mmHg. AVCDs are effective and well tolerated, not only during maintenance therapy, but also in the initial decongestive treatment phase of patients with venous leg edema. [ABSTRACT FROM AUTHOR]

The article discusses a study that was conducted to determine the impact of graduated compression stockings (GCS) on lower leg volume as well as leg complaints in runners during and after exercise. The study concluded that GCS helps to prevent a growth in leg volume just after a running exercise. It presents a report from a questionnaire which states that there was no decline in leg complaints. It recommends for more research to be conducted.

The aim of this study was to examine differences in cycling efficiency between competitive male and female cyclists. Thirteen trained male (mean + SD: 34 ± 8 yr, 74.1 ± 6.0 kg, Maximum Aerobic Power (MAP) 414 ± 40 W, VO2max 61.3 ± 5.4 ml·kg-1·min-1) and 13 trained female (34 ± 9 yr, 60.1 ± 5.2 kg, MAP 293 ± 22 W, VO2max 48.9 ± 6.1 ml·kg-1·min-1) competitive cyclists completed a cycling test to ascertain their gross efficiency (GE). Leg and lean leg volume of all cyclists was also measured. Calculated GE was significantly higher in female cyclists at 150W (22.5 ± 2.1 vs 19.9 ± 1.8%; p < 0.01) and 180W (22.3 ± 1.8 vs 20.4 ± 1.5%; p = 0.01). Cadence was not significantly different between the groups (88 ± 6 vs 91 ± 5 rev·min-1). Lean leg volume was significantly lower for female cyclists (4.04 ± 0.5 vs 5.51 ± 0.8 dm³; p < 0.01) and was inversely related to GE in both groups at 150 and 180W (r = -0.59 and -0.58; p < 0.05). Lean leg volume was shown to account for the differences in GE between the males and females. During an "unloaded" pedalling condition, male cyclists had a significantly higher O2 cost than female cyclists (1.0 ± 0.1 vs 0.7 ± 0.1 L·min-1; p < 0.01), indicative of a greater non-propulsive cost of cycling. These results suggest that differences in efficiency between trained male and female cyclists can be partly accounted for by sex-specific variation in lean leg volume. [ABSTRACT FROM AUTHOR]

In the present study, we examined the effect of thermal stress on the magnitude and pattern of change in leg volume during orthostatic stress and thigh occlusion in humans. Ten healthy volunteers underwent whole-body thermal stress produced by a cool- or hot-water-perfused suit and local heat stress of the calf. During whole-body thermal stress, changes of calf circumference during head-up tilt (HUT) at angles of 15° and 60° for 2 min each were monitored. In the supine position, the distensibility of the calf veins was evaluated from the magnitude and half-time of the change in calf circumference during thigh cuff occlusions at 20, 30, 50, 70, and 80 mmHg. Skin blood flow in the calf was measured by laser-Doppler flowmetry. Skin blood flow increased by [mean (SEM)] 295 (71)% with whole-body heating and decreased by 31 (4)% with whole-body cooling. Local heating of the calf increased skin blood flow in the heated area by 263 (25)%. During HUT, the calf cross-sectional area, calculated from the circumference, increased rapidly during whole-body heating and slowly during the cooling. The magnitude of the increase in calf area with HUT did not alter during whole-body heating, whereas it was reduced during cooling compared with the normothermic control. Whole-body and local heating did not alter the magnitude of change in calf area at a given cuff pressure, whereas whole-body cooling decreased it. The time to the half-maximal response of the change in calf circumference was shortened by 35 (17)% during whole-body heating and by 44 (4)% during local heating, whereas it was prolonged by 31 (16)% during whole-body cooling compared with the normothermic control. These results indicate that the magnitude and the pattern of change in calf volume during the early phase of orthostatic stress are modulated due to the changes in venous distensibility and blood flow in the skin during thermal loading. [ABSTRACT FROM AUTHOR]

Simple Summary: The present study aimed to evaluate the accuracy of the leg volume obtained by the Microsoft Kinect sensor to predict the carcass composition of twenty-two male light lambs. The carcasses were divided into eight cuts, which were grouped according to their commercial value into high-value, medium value, and low-value. Several linear, area, and volume leg measurements were performed to predict cut and carcass composition. The leg volume determined by 3D image reconstruction using Microsoft Kinect sensor and Archimedes principle shows the higher correlations values with cuts and carcass. Additionally, it was observed that the models, which include the leg volume obtained by the Kinect sensor, are very good in predicting the weight of the medium value and leg cuts (R2 of 0.763 and 0.829, respectively). Thus, the results of this study confirm the good ability to estimate cuts and body traits from light lambs with volume measurements, particularly those obtained with the Kinect 3D sensor. This study aimed to evaluate the accuracy of the leg volume obtained by the Microsoft Kinect sensor to predict the composition of light lamb carcasses. The trial was performed on carcasses of twenty-two male lambs (17.6 ± 1.8 kg, body weight). The carcasses were split into eight cuts, divided into three groups according to their commercial value: high-value, medium value, and low-value group. Linear, area, and volume of leg measurements were obtained to predict carcass and cuts composition. The leg volume was acquired by two different methodologies: 3D image reconstruction using a Microsoft Kinect sensor and Archimedes principle. The correlation between these two leg measurements was significant (r = 0.815, p < 0.01). The models to predict cuts and carcass traits that include leg Kinect 3D sensor volume are very good in predicting the weight of the medium value and leg cuts (R2 of 0.763 and 0.829, respectively). Furthermore, the model, which includes the Kinect leg volume, explained 85% of its variation for the carcass muscle. The results of this study confirm the good ability to estimate cuts and carcass traits of light lamb carcasses with leg volume obtained with the Kinect 3D sensor. [ABSTRACT FROM AUTHOR]

Background: Lymphoedema is a chronic condition that causes swelling in the body tissues. Presently, there is no cure for lymphoedema; instead, current treatment is aimed at lifelong management to help control symptoms. Intermittent pneumatic compression (IPC) therapy can be considered as an adjunct to standard lymphoedema care; however, research regarding the efficacy of this treatment modality is limited. Methods: Twenty participants were recruited from an outpatient lymphoedema clinic (South Wales, UK) to a feasibility randomised control trial designed to evaluate the efficacy of an IPC device (LymphAssist, Huntleigh Healthcare) in reducing lower limb volume. The primary objective was to assess feasibility in terms of (1) study feasibility, including recruitment, retention and assessment of outcome measures, and (2) intervention feasibility, including intervention fidelity and acceptability to participants. Participants were randomly assigned to a control group (n = 10) or intervention group (n = 10). The control group received their standard lymphoedema care only for a 6-month period, whereas the intervention group received their standard lymphoedema care plus an IPC device to use for 6 months. A bilateral lower limb assessment and quality of life survey were undertaken at baseline and 3- and 6-month time points. Results: The study recruited to target within the planned time frame with a retention rate of 80%. Issues relating to potential recruitment bias and study attrition were identified and possible solutions explored. In addition, supplementary primary outcome measures that are important to the study population were identified and will be incorporated into the design of future studies. Conclusion: This feasibility study identified that a larger randomised controlled trial investigating the efficacy of home use IPC devices is feasible with modifications to the study protocol. Trial registration: This trial is registered with clinicaltrials.gov (NCT03825263). [ABSTRACT FROM AUTHOR]