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The article deals with the delay between the evolution of functioning of the body and the social revolutionary transition from the Earth people towards Space people. As a result of this natural phenomenon, the legal protection of human rights to life and health for the human explorers of outer space is needed. This need is encouraged by the plans of certain governments and private space companies on accomplishing the mission to Mars in the middle-term perspective. The article follows the scientific proposals to update legal responsibility of states to ensure the life and health of astronauts and space tourists sent by them. The article applies general and special scientific methods to comprehend and study social and legal phenomena and general logic reasoning (abstract reasoning, analogy, analysis, generalization, etc.). Consequently, the article authors conclude that the UN should adopt the Declaration on Human Rights in Space to formalize the legal protection of human representatives sent to space.