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1. Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics.

Author

Van den Broeck F, Heeren S, Maes I, Sanders M, Cotton JA, Cupolillo E, Alvarez E, Garcia L, Tasia M, Marneffe A, Dujardin JC, and Van der Auwera G

Subjects
Animals, Humans, Parasites, Genomics, Leishmania genetics, Leishmaniasis, Cutaneous parasitology, Triploidy
Abstract

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

Published
2023
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