1. Children with lymphoma presenting with hemophagocytic lymphohistiocytosis.
- Author
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Aksu T, Bayhan T, Gülhan B, Çakmakcı S, Oğuz AS, Yaralı N, Özbek NY, and İlhan İ
- Subjects
- Child, Herpesvirus 4, Human, Humans, Epstein-Barr Virus Infections complications, Epstein-Barr Virus Infections diagnosis, Leukemia, Lymphohistiocytosis, Hemophagocytic diagnosis, Lymphoma, Large-Cell, Anaplastic
- Abstract
Background: < 7b > Hemophagocytic lymphohistiocytosis (HLH) may precede malignancy, in particular lymphomas and leukemias. However, the causative factors, appropriate treatment and the prognosis of this association is not established., Case: Herein, we present two patients, one with nodular sclerosing Hodgkin lymphoma (HL) and concomitant Epstein-Barr virus (EBV) infection, and the other with anaplastic large cell lymphoma (ALCL), presented as malignancy associated HLH., Conclusion: In our patients, malignancy directed therapy was sufficient to treat HLH symptoms both at presentation and at recurrence in the second patient.
- Published
- 2020
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