Search

Pd(OAc)2‐catalyzed Sonogashira coupling reactions of alkynes and a variety of aryl halides with 1,3‐bis(5‐ferrocenylisoxazoline‐3‐yl)benzene as an efficient non‐phosphorus ligand under copper‐free conditions are presented. The main advantages over previous methodologies include low catalyst loading (0.2 mol% Pd(OAc)2 and 0.4 mol% ferrocenyl bisoxazoline ligand are sufficient for these coupling reactions), less problematic reaction medium (water–dimethylformamide) and more convenient operation (no requirement for nitrogen protection). [ABSTRACT FROM AUTHOR]

A chiral [M3 L3]6+-type nanobowl reported here was self-assembled from cis-protected mono-palladium complex [(RRdiph)Pd](NO3)2 (where RRdiph= (1 R,2 R)-(+)-1,2-diphenylethylenediamine) as chiral corners and 4,7-phenanthroline ligand ( L) as linkers in aqueous media. The hydrophobic cavity-containing metallo-macrocycle [Pd3 L3]6+·6NO3 ( 1) with a syn, syn, syn orientation has been characterized by 1H NMR spectroscopy, elemental analysis, CD spectra and X-ray diffraction determination. [ABSTRACT FROM AUTHOR]

Two novel isoxazoline N, N-bidentate ligands with ferrocene backbone have been synthesized and employed for the reaction. Among them, 1,3-bis-(5-ferrocenylisoxazoline-3-yl)benzene was found to be thermally stable and a highly effective ligand for Heck in neat water without N2 protection, affording the desired coupling products in good to excellent yield with high diastereoselectivity. The developed catalytic system was also well workable for 1,2-disubstituted alkenes, which were less involved in the for its larger steric hindrance. Copyright © 2014 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Four new palladium pincer complexes incorporating ONO type furoylhydrazone ligands have been prepared in good yields. These palladium complexes were structurally characterized by elemental analysis, infrared, 1H‐ and 13C‐NMR spectra. X‐ray single crystal analyses of Pd1–Pd4 revealed that the metal center adopted a slightly distorted square planar geometry in which the hydrazone bound the metal ion via the phenolic‐O, azomethine‐N and imidolate‐O atoms. Using these ONO pincer complexes as catalyst, excellent yields of biaryls could be obtained for coupling of arylboronic acids with aryl bromides at a low catalyst loading (0.01 mol%). [ABSTRACT FROM AUTHOR]