1. Magnetic resonance imaging of lipoma and atypical lipomatous tumour/well-differentiated liposarcoma: observer performance using T1-weighted and fluid-sensitive MRI.
- Author
-
Doyle AJ, Pang AK, Miller MV, and French JG
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Observer Variation, Sensitivity and Specificity, Lipoma diagnosis, Liposarcoma diagnosis, Magnetic Resonance Imaging methods, Magnetic Resonance Imaging statistics & numerical data, Soft Tissue Neoplasms diagnosis
- Abstract
The aim of this study was to evaluate observer performance using T1-weighted spin-echo and fluid-sensitive MRI sequences in distinguishing between lipoma and atypical lipomatous tumour/well-differentiated liposarcoma (ALT/WDL). Magnetic resonance images of 51 patients with benign lipoma and ALT/WDL of the musculoskeletal system were reviewed. There were 33 benign lipomas and 18 ALT/WDL. The character of septa and nodularity of the fatty tumours on T1-weighted spin-echo sequences and the presence of high signal on fluid-sensitive sequences were assessed. Two independent observers took part. Observer agreement was measured. The two observers achieved sensitivities of 100 and 94% for T1-weighted images and 100% each for fluid-sensitive sequences. Specificities were 76 and 64% for T1-weighted and 70 and 73% for fluid-sensitive images. Observer agreement was very good (kappa 0.87 for T1-weighted and 0.88 for fluid-sensitive images). In distinguishing lipoma from ALT/WDL, observer performance was comparable using T1-weighted and fluid-sensitive MR sequences. High sensitivity and moderately high specificity were attained.
- Published
- 2008
- Full Text
- View/download PDF