1. Outcomes of liver resection for hepatocellular carcinoma in octogenarians.
- Author
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Sanyal S, Kron P, Wylie N, Hildalgo E, Toogood GJ, and Lodge P
- Subjects
- Aged, 80 and over, Hepatectomy adverse effects, Humans, Retrospective Studies, Carcinoma, Hepatocellular surgery, Liver Neoplasms surgery
- Abstract
Background: There is a dearth of information about operative outcomes in patients ≥80 years for hepatocellular carcinoma (HCC) from Western institutions. We compare the result of HCC resections in patients <80 years vs. patients ≥80 years from our institution in the UK., Methods: We conducted a retrospective review of all patients undergoing liver resections for HCC between 2005 and 2015. Demographics, comorbidities, morbidity, mortality and survival were compared between the two age groups., Results: 200 patients underwent resection for HCC in this time period. Nineteen patients were ≥80 years and 181 were <80 years. Comorbidities measured by the Charlson Comorbidity Index were significantly higher in the ≥80 group (p < 0.0001). There was no significant difference in the extent of resection in the two groups. Morbidity and mortality between the <80 years and the ≥80 years group were not significantly different (morbidity 27% vs.16%; p = 0.29) (mortality 7% vs. 0%; p = 0.11). The one-year (83.4% vs. 88.2%; p = 0.83), five-year (56.3% vs. 55.8%; p = 0.83) and the overall survival rate rates (887 days vs. 1035 days; p = 0.66) were not significantly different between the groups., Discussion: Liver resection should not be precluded based on age alone; with good outcomes in patients ≥80 years justifying surgery., (Crown Copyright © 2020. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2020
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