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Highlights: [•] A novel copolymer of PNIPAM and cholesterol was synthesized via ATRP. [•] Eu(III) or Tb(III) was chelation with nitrogen and oxygen atoms of the copolymer. [•] The complexes exhibited excellent fluorescence performance. [•] The complexes had a LCST slighter than copolymer. [•] The fluorescent performance of complexes was temperature sensitive. [ABSTRACT FROM AUTHOR]

A series of novel fluorescent complexes was formed by chelation of the thermosensitive polymers with europium(III) ions. The polymers was synthesized via atom transfer radical polymerization (ATRP), which composed of poly( N -isopropyl acrylamide) (PNIPAM) and 2-amino-2-deoxy- d -glucopyranose( d -glucosamine, GA). The aqueous solutions of the polymers and its Eu(III) complexes exhibited a lower critical solution temperatures (LCSTs), and which were approximately equal to body temperature. The maximum emission intensity of the complexes at 613 nm was enhanced by a factor of approximately 10 relative to that of the corresponding Eu(III) chloride. Cell viability assays suggested that these thermosensitive polymers and Eu(III) complexes showed excellent biocompatibility in vitro. [ABSTRACT FROM AUTHOR]

A series of chain-end functional polymers composed of poly( N -isopropylacrylamide) (PNIPAM) and 2-amino-2-deoxy- d -glucopyranose( d -glucosamine, GA) was synthesized via atom transfer radical polymerization (ATRP). Novel fluorescent complexes of glucosamine-PNI- PAM/Eu(III) were then formed by chelation of the polymers and europium(III) ions. The aqueous solutions of the polymers and its Eu(III) complexes exhibited a lower critical solution temperatures (LCSTs), and which were approximately equal to body temperature. Cell viability assays suggested that these thermosensitive polymers and Eu(III) complexes showed excellent biocompatibility in vitro. [ABSTRACT FROM AUTHOR]