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Objective: To examine the robustness of the published machine learning models in the prediction of extraction vs non-extraction for a diverse US sample population seen by multiple providers., Setting and Sample Population: Diverse group of 838 patients (208 extraction, 630 non-extraction) were consecutively enrolled., Materials and Methods: Two sets of input features (117 and 22) including clinical and cephalometric variables were identified based on previous studies. Random forest (RF) and multilayer perception (MLP) models were trained using these feature sets on the sample population and evaluated using measures including accuracy (ACC) and balanced accuracy (BA). A technique to identify incongruent data was used to explore underlying characteristics of the data set and split all samples into 2 groups (G1 and G2) for further model training., Results: Performance of the models (75%-79% ACC and 72%-76% BA) on the total sample population was lower than in previous research. Models were retrained and evaluated using G1 and G2 separately, and individual group MLP models yielded improved accuracy for G1 (96% ACC and 94% BA) and G2 (88% ACC and 85% BA). RF feature ranking showed differences between top features for G1 (maxillary crowding, mandibular crowding and L1-NB) and G2 (age, mandibular crowding and lower lip to E-plane)., Conclusions: An incongruent data pattern exists in a consecutively enrolled patient population. Future work with incongruent data segregation and advanced artificial intelligence algorithms is needed to improve the generalization ability to make it ready to support clinical decision-making., (© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Research in computer-aided diagnosis (CAD) and the application of artificial intelligence (AI) in the endoscopic evaluation of the gastrointestinal tract is novel. Since colonoscopy and detection of polyps can decrease the risk of colon cancer, it is recommended by multiple national and international societies. However, the procedure of colonoscopy is performed by humans where there are significant interoperator and interpatient variations, and hence, the risk of missing detection of adenomatous polyps. Early studies involving CAD and AI for the detection and differentiation of polyps show great promise. In this appraisal, we review existing scientific aspects of AI in CAD of colon polyps and discuss the pitfalls and future directions for advancing the science. This review addresses the technical intricacies in a manner that physicians can comprehend to promote a better understanding of this novel application.

Despite the increasing rate of detection of incidental pancreatic cystic lesions (PCLs), current standard-of-care methods for their diagnosis and risk stratification remain inadequate. Intraductal papillary mucinous neoplasms (IPMNs) are the most prevalent PCLs. The existing modalities, including endoscopic ultrasound and cyst fluid analysis, only achieve accuracy rates of 65–75% in identifying carcinoma or high-grade dysplasia in IPMNs. Furthermore, surgical resection of PCLs reveals that up to half exhibit only low-grade dysplastic changes or benign neoplasms. To reduce unnecessary and high-risk pancreatic surgeries, more precise diagnostic techniques are necessary. A promising approach involves integrating existing data, such as clinical features, cyst morphology, and data from cyst fluid analysis, with confocal endomicroscopy and radiomics to enhance the prediction of advanced neoplasms in PCLs. Artificial intelligence and machine learning modalities can play a crucial role in achieving this goal. In this review, we explore current and future techniques to leverage these advanced technologies to improve diagnostic accuracy in the context of PCLs. [ABSTRACT FROM AUTHOR]

Task‐incremental learning (Task‐IL) aims to enable an intelligent agent to continuously accumulate knowledge from new learning tasks without catastrophically forgetting what it has learned in the past. It has drawn increasing attention in recent years, with many algorithms being proposed to mitigate neural network forgetting. However, none of the existing strategies is able to completely eliminate the issues. Moreover, explaining and fully understanding what knowledge and how it is being forgotten during the incremental learning process still remains under‐explored. In this paper, we propose KnowledgeDrift, a visual analytics framework, to interpret the network forgetting with three objectives: (1) to identify when the network fails to memorize the past knowledge, (2) to visualize what information has been forgotten, and (3) to diagnose how knowledge attained in the new model interferes with the one learned in the past. Our analytical framework first identifies the occurrence of forgetting by tracking the task performance under the incremental learning process and then provides in‐depth inspections of drifted information via various levels of data granularity. KnowledgeDrift allows analysts and model developers to enhance their understanding of network forgetting and compare the performance of different incremental learning algorithms. Three case studies are conducted in the paper to further provide insights and guidance for users to effectively diagnose catastrophic forgetting over time. [ABSTRACT FROM AUTHOR]

Abstract: This paper provides a new age estimation approach, which distinguishes itself with the following three contributions. First, we combine distance metric learning and dimensionality reduction to better explore the connections between facial features and age labels. Second, to exploit the intrinsic ordinal relationship among human ages and overcome the potential data imbalance problem, a label-sensitive concept and several imbalance treatments are introduced in the system training phase. Finally, an age-oriented local regression is presented to capture the complicated facial aging process for age determination. The simulation results show that our approach achieves the lowest estimation error against existing methods. [Copyright &y& Elsevier]