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Recent developments in the biology of malignant gliomas have demonstrated that glioma cells interact with neurons through both paracrine signaling and electrochemical synapses. Glioma-neuron interactions consequently modulate the excitability of local neuronal circuits, and it is unclear the extent to which glioma-infiltrated cortex can meaningfully participate in neural computations. For example, gliomas may result in a local disorganization of activity that impedes the transient synchronization of neural oscillations. Alternatively, glioma-infiltrated cortex may retain the ability to engage in synchronized activity in a manner similar to normal-appearing cortex but exhibit other altered spatiotemporal patterns of activity with subsequent impact on cognitive processing. Here, we use subdural electrocorticography to sample both normal-appearing and glioma-infiltrated cortex during speech. We find that glioma-infiltrated cortex engages in synchronous activity during task performance in a manner similar to normal-appearing cortex but recruits a diffuse spatial network. On a temporal scale, we show that signals from glioma-infiltrated cortex have decreased entropy, which may affect its ability to encode information during nuanced tasks such as production of monosyllabic versus polysyllabic words. Furthermore, we show that temporal decoding strategies for distinguishing monosyllabic from polysyllabic words were feasible for signals arising from normal-appearing cortex but not from glioma-infiltrated cortex. These findings inform our understanding of cognitive processing in chronic disease states and have implications for neuromodulation and prosthetics in patients with malignant gliomas.

Recently Mobile adhoc networks (MANETs) have received the great attention of researchers as these models provide a wide range of applications. But MANET nodes are prone to various security threats. To overcome this issue, many trust management frameworks have been implemented in the literature. It has been found that the use of machine learning can predict trust values more efficiently. However, machine learning performance suffers from the hyper-parameters tuning and over-fitting issues. Therefore, in this paper, novel trust management is proposed. initially, the Adaptive neuro-fuzzy inference system (ANFIS) is used to train the trust prediction model. Thereafter, a non-dominated sorting genetic algorithm-III (NSGA-III) is used to tune the hyper-parameters of the ANFIS model. Precision, recall, and root mean squared error metrics are used to design a multi-objective fitness function. Optimized link state routing (OLSR) protocol is used for comparative analyses purpose. Three different attacks are applied on the designed network i.e., link spoofing, jellyfish, and gray hole attacks to obtain the dataset. Comparative analysis reveals that the proposed trust evaluation model outperforms the competitive trust evaluation models in terms of various performance metrics such as routing overheads, average end to end latency, packet delivery ratio, and throughput. Thus, the proposed protocol is more secure against various security threats. [ABSTRACT FROM AUTHOR]

The efficiency and reliability of radio over free space optical communication may be significantly degraded by different weather conditions, thus leading to decrease and increase of signal to noise ratio (SNR) and bit error rate (BER) of the recovered signal respectively. Therefore, real time optical performance estimation is of utmost importance to enable the awareness of channel conditions and for achieving high quality of service. In this work, a terrestrial radio over free space optics (RoFSO) system has been investigated by employing 32-QAM and 64-QAM OFDM modulation schemes under rain, haze and clear weather conditions. Performance of the system is further estimated by employing artificial neural networks (ANN), k-nearest neighbours (KNN) and decision tree (DT) machine learning (ML) techniques with root mean square error (RMSE) and coefficient of determination (R2) as performance metrices. Atmospheric attenuation and different internal system parameters act as input features with BER and SNR of the received signal as the modelling targets. The best performing model has been found to be by applying an ANN approach with lower RMSE values for SNR and BER as 1.87 and 1.26 respectively. The value of R2 predicted by the model are 0.97139 and 0.97802 for SNR and BER data sets respectively. [ABSTRACT FROM AUTHOR]