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Your search keyword '"Guang-Tong Chen"' showing total 4 results
Start Over Author "Guang-Tong Chen" Topic magnetic resonance spectroscopy
4 results on '"Guang-Tong Chen"'

1. Evolvulins I and II, Resin Glycosides with a Trihydroxy Aglycone Unit from

Author

Bo-Yi, Fan, Yun, Lu, Min, Yang, Jian-Lin, Li, and Guang-Tong, Chen

Subjects
Magnetic Resonance Spectroscopy, Molecular Structure, Cell Line, Tumor, MCF-7 Cells, Humans, Oligosaccharides, Glycosides, Drug Screening Assays, Antitumor, Convolvulaceae, Antineoplastic Agents, Phytogenic, Resins, Plant
Abstract

Evolvulins I and II (

Published
2019

2. NMR spectral assignments of isoprenylated flavanones fromSophora tonkinensis

Author

Zhi-Qiang Lu, Xingnuo Li, De-An Guo, Li-Jun Wu, Hai-Xia Yan, Min Yang, Guang-Tong Chen, Na Sha, Shu-Hong Guan, and Hui-Ming Hua

Subjects
Flavonoids, Carbon Isotopes, Magnetic Resonance Spectroscopy, biology, Chemistry, Stereochemistry, Molecular Conformation, Sophora tonkinensis, Stereoisomerism, General Chemistry, Reference Standards, Carbon-13 NMR, biology.organism_classification, Plant Roots, Flavanones, Proton NMR, General Materials Science, Protons, Spectral data, Sophora, Heteronuclear single quantum coherence spectroscopy
Abstract

The phytochemical investigation of extracts from the roots of Sophora tonkinensis yielded three new isoprenylated flavanones, the tonkinochromanes F (2), G (3), and H (5), along with four known compounds. Structural elucidation of the compounds were established on the basis of spectral data, particularly by the use of 1D NMR and several 2D shift-correlated NMR pulse sequences (1H1H COSY, HSQC, HMBC, and ROESY). Copyright © 2008 John Wiley & Sons, Ltd.

Published
2008
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3. Two new lignans fromMentha spicataL

Author

Jian Zheng, Li-Jun Wu, Guang-Tong Chen, Hui-Yuan Gao, and Bin Wu

Subjects
Magnetic Resonance Spectroscopy, Mentha spicata, Pharmaceutical Science, Pyrogallol, Pharmacognosy, Lignans, Mass Spectrometry, Analytical Chemistry, chemistry.chemical_compound, food, Drug Discovery, Botany, Benzofurans, Spicatolignan B, Pharmacology, Lignan, chemistry.chemical_classification, Guaiacol, Organic Chemistry, Glycoside, General Medicine, food.food, Complementary and alternative medicine, chemistry, Molecular Medicine
Abstract

Two new lignans named spicatolignan A (1) and spicatolignan B (2) have been isolated from the whole herbs of Mentha spicata L.

Published
2007
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4. Characterization of pumpkin polysaccharides and protective effects on streptozotocin-damaged islet cells

Author

Ji-Liang Xu, Hong-Yan Zhu, Guang-Tong Chen, and Guo-Liang Meng

Subjects
Chromatography, Gas, Magnetic Resonance Spectroscopy, Size-exclusion chromatography, Apoptosis, Polysaccharide, Nitric Oxide, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, Islets of Langerhans, Column chromatography, Cucurbita, Polysaccharides, Malondialdehyde, Drug Discovery, Spectroscopy, Fourier Transform Infrared, medicine, Animals, bcl-2-Associated X Protein, chemistry.chemical_classification, geography, geography.geographical_feature_category, Chromatography, Reverse Transcriptase Polymerase Chain Reaction, Superoxide Dismutase, Monosaccharides, General Medicine, Streptozotocin, Islet, Rats, Molecular Weight, Complementary and alternative medicine, Pyranose, Biochemistry, chemistry, Chromatography, Gel, Dismutase, Gas chromatography, medicine.drug
Abstract

The polysaccharides from pumpkin fruit (PP) were obtained and purified by hot-water extraction, anion-exchange chromatography, and gel column chromatography. The physicochemical properties of PP were determined by gel filtration chromatography, gas chromatography, fourier transform infrared (FTIR) spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy. Results indicated that the molecular weight of PP was about 23 kDa and PP was composed of D-Arabinose, D-Mannose, D-Glucose, and D-Galactose with a molar ratio of 1 : 7.79 : 70.32 : 7.05. FTIR and NMR spectra indicated that PP was the polysaccharide containing pyranose ring. Additionally, PP protected islets cells from streptozotocin (STZ) injury in vitro via increasing the levels of super-oxide dismutase (SOD) and malondialdehyde (MDA) and reducing the production of NO. The experiment of reverse transcriptase-polymerase chain reaction further proved that PP inhibited apoptosis via modulating the expression of Bax/Bcl-2 in STZ-damaged islet cells. In conclusion, PP could be explored as a novel agent for the treatment of diabetes mellitus.

Published
2014

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