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Your search keyword '"I N, Maĭskiĭ"' showing total 9 results
Start Over Author "I N, Maĭskiĭ" Topic male
9 results on '"I N, Maĭskiĭ"'

1. [Changes in the immunologis status of the body during carcinogenesis detected by the physico-chemical characteristics of cells of the immunocompetent system]

Author

E N, Stepanova, G P, Aĭrapet'ian, and I N, Maĭskiĭ

Subjects
Male, Binding Sites, Thigh, 9,10-Dimethyl-1,2-benzanthracene, T-Lymphocytes, Animals, Lymph Nodes, Lymphocytes, Sarcoma, Experimental, Anilino Naphthalenesulfonates, Rats
Abstract

The state of cell population of the lymph nodes and the thymus was studied on a model of rat sarcoma of the hip(induced by dimethlbenzanthracene) by the method of fluorescent sounds. Statistically significant changes of incorporation of the negatively charged sound 1-anilino-8-naphthalinosulfonate (ANS) into cell suspension, depending on the stage of sarcoma development, were detected. The appearance of cell forms with a lesser hydrophobic character of the surface and with less binding points for the ANS were noted at the early carcinogenesis periods. It is supposed that these cells were referred to immature ones. A conclusion was drawn on the applicability of the method of fluorescent sound for recording changes in the immunological state of the organism in carcinogenesis.

Published
1977

2. [Structuro-functional changes in lymphoid populations during the course of carcinogenesis]

Author

E N, Stepanova, G P, Aĭrapet'ian, and I N, Maĭskiĭ

Subjects
Male, B-Lymphocytes, Time Factors, 9,10-Dimethyl-1,2-benzanthracene, T-Lymphocytes, Animals, Cell Count, Complement C3, Lymph Nodes, Sarcoma, Experimental, Thymus Gland, Rats, Receptors, Complement
Abstract

A comparative study was made of the percentage of cells bearing the receptor for the third component of the complement (LRC) and of the total cell content in the rat lymphoid organs as related to the time course of cancerogenesis. It was shown that impairment of the maturation processes in the thymus and in the peripheral organs (lymph nodes, blood) of the immunocompetent systems produces changes in intercellular interactions, reflected by accumulation of B cells, i. e. LRC, and their delayed maturation to antibody producers.

Published
1980

3. [Thermo-stable tumor-associated antigens in the serum of tumor-bearing animals and in tissue cultures of malignant tumors]

Author

M S, Lomakin, A S, Larin, and I N, Maĭskiĭ

Subjects
Male, Immunodiffusion, Antigens, Neoplasm, Chinchilla, 9,10-Dimethyl-1,2-benzanthracene, Animals, Female, Neoplasms, Experimental, Rabbits, Immunoelectrophoresis
Abstract

Gel precipitation and immunoelectrophoresis have demonstrated the presence of thermostable tumour-associated antigens in blood serum from tumour-bearing rats and culture supernatant of malignant cells. These antigens have the electrophoretic mobility in the zones of beta-, alpha- and alpha 1-globulins.

Published
1980

4. [Thermostable antigens of malignant tumors and normal tissues of experimental animals]

Author

M S, Lomakin, A S, Larin, and I N, Maĭskiĭ

Subjects
Male, Epitopes, Immunodiffusion, Hot Temperature, Organ Specificity, 9,10-Dimethyl-1,2-benzanthracene, Animals, Female, Neoplasms, Experimental, Rabbits, Antigens, Immunoelectrophoresis, Rats
Abstract

Gel precipitation and immunoelectrophoresis tests tests demonstrated the presence of thermostable antigens in dimethylbenzanthracene-induced malignant tumours of the muscle tissues of Wistar rats. These antigens were relatively tissue-specific for the tumours, amniotic fluid and the uterus on the one hand, and for the lung, spleen, and the serum on the other hand. The thermostable antigens of the tumours and the amniotic fluid had the electrophoretic mobility in the zone of alpha and alpha1-globulins.

Published
1978

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