1. Risk of rabies transmission and adverse effects of postexposure prophylaxis in health care workers exposed to a fatal case of human rabies
- Author
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Hervé Bourhy, Claude Flamand, Didier Hommel, Magalie Demar, Aba Mahamat, Philippe Dussart, Jean-Michel Fontanella, André Spiegel, Félix Djossou, Jean-Baptiste Meynard, Unité des Maladies Infectieuses et Tropicales [Cayenne, Guyanne Française], Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP), Laboratoire Hospitalo-Universitaire de Parasitologie-Mycologie, Coordination Régionale de la lutte contre le Virus de L'Immunodéficience Humaine (COREVIH)-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française]-Université des Antilles (UA), Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), Cellule Interrégionale d'Epidémiologie Antilles-Guyane, Cellule interrégionale d'épidémiologie Antilles-Guyane [CIRE], Centre Collaborateur de l'OMS pour la Rage - Dynamique des lyssavirus et adaptation à l'hôte (CC-OMS), Institut Pasteur [Paris] (IP), Centre National de Référence de la Rage-Dynamique des Lyssavirus et adaptation à l'hôte (CNR), and Institut Pasteur [Paris]
- Subjects
Adult ,Male ,medicine.medical_specialty ,Epidemiology ,Rabies ,Health Personnel ,[SDV]Life Sciences [q-bio] ,MESH: Risk Assessment ,Risk Assessment ,MESH: Occupational Exposure ,03 medical and health sciences ,0302 clinical medicine ,MESH: Rabies ,Occupational Exposure ,Health care ,Hospital-acquired infection ,MESH: French Guiana ,medicine ,Humans ,030212 general & internal medicine ,Intensive care medicine ,Rabies transmission ,Adverse effect ,Risk management ,0303 health sciences ,MESH: Humans ,030306 microbiology ,business.industry ,Health Policy ,Public Health, Environmental and Occupational Health ,MESH: Rabies Vaccines ,MESH: Adult ,medicine.disease ,MESH: Male ,3. Good health ,French Guiana ,Vaccination ,Infectious Diseases ,Rabies Vaccines ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,MESH: Health Personnel ,business ,Risk assessment ,Post-Exposure Prophylaxis ,MESH: Post-Exposure Prophylaxis - Abstract
Presented in part as an oral communication at the 10th Journées Nationales d’Infectiologie, Marseille, France, June 10-12, 2009.; International audience; On May 27, 2008, a patient died from rabies at the Cayenne Hospital in French Guiana. Postexposure prophylaxis vaccination was implemented for all health care workers exposed to this patient. Examining the management of such a rare risk reveals important factors in the education of personnel who may have contact with a patient with rabies, to permit appropriate risk assessment and reduce unnecessary postexposure prophylaxis, taking into account the risks and costs of adverse events.
- Published
- 2012