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To evaluate the reliability and validity of the Chinese version of the Johns Hopkins Adapted Cognitive Exam (ACE) in neurological intensive care unit patients.The English version of the ACE was translated and adapted into Chinese. The cognitive function of 40 critically ill NICU patients was assessed using the Chinese version of the ACE and the Mini-mental state examination (MMSE) battery. Scores on the ACE and MMSE were analyzed, and the scale's content validity, construct validity, concurrent validity, internal consistency, inter-rater reliability, and test-retest reliability metrics were determined.The coefficients for the Pearson correlations between individual item scores and total score ranged from 0.617 to 0.938, and content validity was good. ACE scores were significantly correlated with MMSE scores(r = 0.822, p0.05). Five factors were extracted during the principal component analysis, the cumulative contribution of which was 85.90%. Overall, the factor loading of each item was 0.5, and the scale had good construct validity. The Chinese version of the ACE demonstrated good internal consistency (Cronbach'α = 0.756), inter-rater reliability (ICC0.95), and test-retest reliability (ICC = 0.652-0.979).The results of this study suggest that the Chinese version of the ACE was a reliable and valid screening tool for cognitive impairment in NICU patients. List of abbreviations: ACE: (Johns Hopkins Adapted Cognitive Exam); NICU : (neurological intensive care unit); MMSE: (Mini-Mental State Examination); SPSS: (the Statistical package for the Social Sciences); ICC: (Intra-class Correlation Coefficients); SCCM: (Society of Critical Care Medicine); PICS: (post-intensive care syndrome); ARDS:(acute respiratory distress syndrome); MoCA; (Montreal Cognitive Assessment); EFA: (exploratory factor analysis).

The aims of this study were to systematically evaluate and comparatively analyse the mental health status of left-behind children (LBC) in China and to provide a scientific basis for mental intervention and healthy education for LBC. Six electronic databases were searched for studies (published from 1 January 2010 to 5 March 2018) of the mental health of LBC using the Mental Health Test scale. We only selected original articles that either reported the incidence of serious mental health status or the means and standard deviations of each factor score of the scale. The pooled rates and weighted mean difference were calculated. The results indicated that the incidence of serious mental health status of LBC is nearly 2.7 times higher than that of non-LBC. The scores for most of the factors analysed by the Mental Health Test of LBC were higher than those of non-LBC. In addition, the mental health status of left-behind girls is worse than that of left-behind boys. Except for impulsive tendency, there was no significant difference in the mental health status of LBC in primary and junior high schools. In terms of the different types of guardianship, the mental health status of LBC under a grandparent's guardianship and parental peer' guardianship is more serious than that of LBC under a single-parent guardianship. The mental health status of LBC is poor, particularly for left-behind girls. The primary mental problems faced by LBC are learning anxiety, social anxiety and physical symptoms. It is necessary to develop more targeted measures to prevent and manage LBC.

Background: Coronal diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient (ADC) values have gradually become applied (following conventional axial DW-MRI) in the renal analysis. To explore whether data obtained using coronal DW-MRI are comparable with those derived using axial DW-MRI, this preliminary study sought to assess the agreement in renal ADC values between coronal DW-MRI and axial DW-MRI. Methods: Thirty-four healthy volunteers were enrolled in the study; written consents were obtained. All subjects underwent respiratory-triggered axial and coronal DW-MRI using a 1.5-MR system with b values of 0 and 800 s/mm 2 . The signal-to-noise ratios (SNRs) of the two DW-MRI sequences were measured and statistically compared using the paired t-test. The extent of agreement of ADC values of the upper pole, mid-pole, and lower pole of the kidney; the mean ADC values of the left kidney and right kidney; and the mean ADC values of the bilateral kidneys were evaluated via calculation of intraclass correlation coefficients (ICCs) or Bland-Altman method between the two DW-MRI sequences. Results: The SNR of coronal DW-MR images was statistically inferior to that of axial DW-MR images (P < 0.001). The ICCs of the ADC values of each region of interest, and the mean ADC values of bilateral kidneys, between the two sequences, were greater than 0.5, and the mean ADCs of the bilateral kidneys demonstrated the highest ICC (0.869; 95% confidence interval: 0.739-0.935). In addition, 94.1% (32/34), 94.1% (32/34), and 97.1% (31/34) of the ADC bias was inside the limits of agreement in terms of the mean ADC values of the left kidneys, right kidneys, and bilateral kidneys when coronal and axial DWI-MRI were compared. Conclusions: ADC values derived using coronal DW-MRI exhibited moderate-to-good agreement to those of axial DW-MRI, rendering the former an additional useful DW-MRI method, and causing the ADC values derived using the two types of DW-MRI to be comparable.

The purpose of this study was to investigate the fate of transplanted cells in the central zone of myocardial infarction (MI), and to clarify the relationship between the injection-site impact and the efficacy of cell therapy. MI was created by coronary ligation in female rats. Three weeks later, 3-million labelled male bone marrow mesenchymal stem cells (BMSCs) were directly injected into the border (BZC group) or central zone (CZC group) of MI area. As a control, culture medium was injected into the same sites. Cell survival was evaluated by quantitative real-time polymerase chain reaction, and apoptosis was assayed with TUNEL and caspase-3 staining. Four weeks after transplantation, heart function and cardiac morphometry were evaluated by echocardiography and Masson’s Trichrome staining, respectively. Angiogenesis and myogenesis were detected by immunofluorescence staining. After cell transplantation into the border or central zone, there was no cell migration between the different zones of MI. BMSCs in the CZC group exhibited no difference in apoptotic percentage, in the long-term survival, when compared with those in the BZC group. However, they did effectively promote angiogenesis and cellular myogenic differentiation. Although cell delivery in the central zone of MI had no effect on the recovery of heart function compared with the BZC group, the retained BMSCs could still increase the scar thickness, and subsequently exhibit a trend in the reverse remodelling of ventricular dilation. Hence, we concluded that the central zone of MI should not be ignored during cell-based therapy. Multiple site injection (border+central zone) is strongly recommended during the procedure of cell transplantation.

To document the magnetic resonance (MR) imaging features of multifocal clear cell renal cell carcinoma (RCC).The MR findings of 11 cases of pathologically-proved multifocal clear cell RCCs were reviewed retrospectively from January 2008 to December 2010. All patients underwent MR in a 1.5 T or a 3.0 T scanner. The MR features of the lesions were analyzed, with emphasis on the location, the signal intensity on T2-weighted imaging (T2WI), in regards to pseudocapsule, lipid component, hemorrhage, cystic degeneration, and enhancement pattern. Meanwhile, from these six aspects, the MR appearance of renal cell carcinomas occurring in the same patient were compared.24 tumors (mean diameter, 3.1 cm) in the 11 patients (6 men, 5 women; age range, 36-69 years; mean age, 50.6 years) were detected. Multiple lesions in bilateral kidneys were found in 9 patients (9/11), while in unilateral kidney 2 patients (2/11). Hyperintensity on T2WI were observed in 16 lesions (16/24), while hypointensity 8 lesions (8/24); pseudocapsule was seen in all lesions; hemorrhage in 4 lesions (4/24), lipid component in 12 lesions (12/24) and cystic degeneration in 18 lesions (18/24), persistent enhancement in 22 lesions (22/24) and rapid wash-out pattern in 2 lesions (2/24). All lesions showed moderate or intense enhancement. The MR appearances of lesions in the same patient were identical in 5 cases (5/11), different in 6 cases (6/11).Multifocal clear cell RCCs occur more commonly in bilateral kidneys simultaneously than in unilateral kidney. The lesions in the same patient can show different MR imaging features, which probably facilitate the preoperative determination.

To document the MRI features of Chromophobe cell carcinoma and to explore whether MR features vary with the tumor size.MRI features of 34 patients (16 male, 18 female, age range from 24 - 61, average age is 49 years old), totally 35 focuses with histologically proved chromophobe cell carcinoma were studied retrospectively. All the patients underwent MR plain and dynamic contrast-enhanced scan before their surgery. Variation of signal intensity (3D LAVA) and ADC values of the lesions, and the analysis of images of T1WI, T2WI and chemical shift were all evaluated on the GE Advantage 4.4 work station. All lesions were categorized into 2 groups (tumor diameter ≤ 4 cm, or4 cm). The difference of imaging characteristics between these two groups was analyzed using Fisher exact test. Signal intensity variation and ADC values were analyzed by using one-way ANOVA method.None of the 35 cases contained fat or lipid. On T2WI 27 cases showed slightly low signal intensity (77.1%). In all cases, 4 appeared local cystic change (11.4%); 4 spotty hemorrhage (11.4%); 5 necrosis (covering less than 20% of whole tumor) (14.2%); 30 clear pseudo capsule (85.7%); 29 round-like lesions (the difference among the length, width and height was within 0.5 cm) (82.8%); and no cases showed signs of invasiveness or metastasis. The average changes of signal intensity of all the 35 cases were 119.8% on cortex period, 176.4% on medulla period and 154.5% on delayed phase. The mean ADC value of tumor was 1.08 ± 0.28×10(-3)mm(2)/s. 35 lesions were divided into two groups , 21 in group 1(diameter ≤ 4 cm) and 14 in group 2 (diameter4 cm). Cystic degeneration was seen in 0/21 in group 1 versus 4/14 in group 2 respectively, and hemorrhage 0/21 versus 4/14, necrosis 0/21 versus 5/14 , central scar 2/21 versus 8/14. The difference of these findings between two groups demonstrated statistical significance (P0.05). Variation of signal intensity and ADC values in two groups has no statistical significance.The MR features of Chromophobe renal cell carcinoma were hypointensity on T2WI, clear pseudocapsule, However, cystic degeneration, hemorrhage, necrosis and central scar are more common in larger tumors.

To explore the suicide intention and its influential factors among primary and junior high school students in rural areas of Anhui province, in order to provide evidence for early intervention related to mental health problems.All students from 3 junior high and 5 primary schools in Changfeng county of Anhui were recruited as the study subjects using the cluster sampling method. Data were collected by using Children's Depression Inventory, the Family APGAR Index, the Trait Coping Style Questionnaire, the Children's Self-Esteem Scale, Social Anxiety Scale for Children, and the Quality of Life Scale. Chi-square test and Logistic regression were used to analyze the suicidal ideation and its influential factors respectively.8.64% (252/2917) of the studied children had suicidal ideation. Out of them, 9.80% (166/1694) and 7.03% (86/1223) were left-behind or non-left-behind children. There was statistically significant difference on suicide ideation between the left-behind children and non-left-behind children (P = 0.015). Data from the multivariate logistic regression analysis showed that social anxiety and negative coping style were the risk factors for suicidal ideation (P0.05) while better family function and quality of life were the protective factors of suicidal ideation (P0.05).Suicide ideation was relatively prevalent among rural children in Anhui province. Family, school and society should carry out different kinds of preventive measures to prevent suicide related behaviors in children from this area.

To find out whether the effects of childhood physical abuse on internet addiction disorder in adolescence could be mediated by self-esteem.3798 high school students selected from 76 classes in Grade One and Grade Two, were asked to fill in the anonymous questionnaire, which including the demographic characteristics of students, Young's Internet Addiction Scale, Parent-Child Conflict Tactics Scales and Rosenberg's Self-Esteem Scale.Childhood physical abuse could directly predict less self-esteem and internet addiction disorder (r = -0.108, P0.01, r = 0.057, P0.01) and had significant indirect effects on internet addiction disorder which could be mediated through self-esteem (a = -0.703, standardized b = -0.104, z = 5.052, P0.001). Self-esteem had mediated 22.5% of the childhood physical abuse cases on their internet addiction disorders during the period of adolescence.Self-esteem could partially mediate the relationship between childhood physical abuse and internet addiction disorder. The mediating roles of self-esteem suggested that salient leverage points could make a change through empowerment training, self-esteem group training on self-esteem enhancement in the stage of adolescence.

To understand the status and influential factors of those neglect of left-behind children in rural area, and to provide bases for the development of intervention measures.2917 students were selected as the study subjects from Changfeng county of Anhui province with cluster sampling method and were evaluated by a Parents-Child Conflict Tactics Scales and questionnaire on influential factors.1694 left-behind children, accounted for 58.1% of the total students, were surveyed in this investigation. The prevalence rates of neglect, among total children, left-behind children, non-left-behind children were 67.4%, 70.2%, 63.5%, respectively. The prevalence of neglect among left-behind children was higher than that among non-left-behind children (χ(2) = 14.322, P0.000). There were no significant associations with the neglect rate of left-behind children regarding gender or age differences. Result from multivariate logistic regression analysis indicated that the neglect among the left-behind children were associated with family dysfunction (OR values of moderate and serious family dysfunctions compared to good family function were 1.628 and 2.341, respectively) and the rate of keeping in touch with parents (OR values of sometimes and seldom keeping in touch compared to regular in touch were 1.299 and 1.844, respectively). The starting age of being left-behind (OR values of starting age that being left-behind from 6 to 10 and ≤ 5 years relative to starting age of left-behind ≥ 11 years were 0.703 and 0.630, respectively) appeared to be the protection factor to the neglect of those left-behind children.Our findings indicated that the status of neglect among the left-behind children was serious. Prevention programs on the issue should target on a number of factors, including the characteristics of the children them-selves, as well as on the family of the children.

To describe the current epidemiological characteristics of injuries among primary and middle school students in one rural area of Anhui province and to explore the relationship between the ways of coping and related injuries.Through cluster sampling methods, all students from 3 to 9 grades in 5 primary schools and 3 middle schools in Changfeng county of Anhui province were investigated with questionnaire. All participants completed an anonymous questionnaire concerning their experiences with injuries during the 12 months preceding the survey. The ways of coping to injuries were evaluated by Trait Coping Style Questionnaire. Factors associated with injuries were identified using a negative binomial regression analysis.Of 2917 students, the annual event-based rate of injuries was 17.4 per 100 students. Positive coping score had no significant differences between the injury and non-injury groups (33.98 ± 6.38 vs. 33.66 ± 6.37) (t = 0.979, P = 0.328). The score of negative coping style was higher in injury group than in non-injury group (27.65 ± 7.79 vs. 26.54 ± 7.62) (t = 2.775, P = 0.006). Statistically, the annual injury rates were significantly different in three groups on their negative styles of coping (χ(2) = 6.131, P = 0.013). Data from the multivariable negative binomial regression analysis, after adjusted for demographic characteristics, showed no significant difference on the relationship between positive coping style and injury incidence. Those with moderate negative style of coping had lower risks compared to those with highly negative one (IRR = 0.77, 95%CI: 0.63 - 0.94).Negative ways of coping was an important risk factor for injuries. Data from our research suggested that psychological preventive measure need to be taken to improve the style of coping. It was also important to promote the related personality development in planning the strategies for future prevention on injuries.

To examine the association between internet addiction and suicidal behaviors in adolescence and to explore whether the association could be partly or fully accounted by depression or/and behaviors related to the impulsivity.A total of 3507 urban adolescent students in Hefei were administered to complete the questionnaire concerning interact addiction disorder (IAD), suicidal behaviors during the 12 months preceding the survey, behaviors related to the impulsivity, Center for Epidemiologic Studies Depression Scale and early childhood adversities, respectively. Hierarchical logistic regressions were used to evaluate the associations and possible roles of depression and behaviors related to the impulsivity between internet addition and suicidal behaviors after adjustment for confounding factors.Of the 3507 participants, 5.2% were diagnosed as IAD, 27.4% reported suicidal ideation during the 12 months preceding the survey, with another 9.5% had a plan and 2.6% had an attempt. Internet addition was associated with suicidal ideation (OR = 1.79, 95%CI: 1.32 - 2.44), plan (OR = 2.32, 95%CI: 1.57 - 3.42), and attempt (OR = 2.08, 95%CI: 1.03 - 4.22). After adjustment for potential confounding factors, the association between internet addition and attempt was insignificant. When depression and behaviors related to the impulsivity were entered into Hierarchical regression respectively, the associations between internet addition, suicidal ideation and plan were substantially reduced. While internet addition was enter into Hierarchical regression, the associations between depression, behaviors related to the impulsivity, suicidal ideation and plan were not reduced.Adolescent internet addition seems to be associated with suicidal ideation and plan, and the association is possibly mediated by depression and behaviors related to the impulsivity.

To study the newborn's Apgar score in 'one minute' and relevant factors.One year inpatient woman from a Maternal and Child Health Hospital of Anhui province were selected by cluster sampling method and newborn asphyxia situation was investigated using Apgar score and self-designed questionnaire.The Apgar score in 'one minute' which marking 8 to 10, 4 to 7 and 0 to 3 were found in 1875 (73.78%), 426 (16.77%) and 240 infants (9.45%) respectively. The average Apgar score in 'one minute' and five minutes were (7.69 +/- 2.27) and (9.01 +/- 1.89) respectively, The Apgar score in 'one minute' was significantly correlated with that of five minutes (Pearson coefficient correlation r = 0.841, P = 0.00). Ordinal regression analysis revealed that parturient age (OR = 1.04), being farmer (OR = 2.22), parity (OR = 1.26), assistant vaginal delivery (OR = 4.93), caesarean section (OR = 1.95), pregnancy-induced hypertension syndrome (OR = 1.42), albuminuria in gestational period (OR = 1.44), newborn being male (OR = 1.23), low birth weight (OR = 2.94), inborn abnormality (OR = 12.12), premature birth (OR = 1.22) and complications of delivery (OR = 5.04) were risk factors while the number of years under study (OR = 0.91), prenatal check-up (OR = 0.48), body length of newborn infant (OR = 0.88) and single birth (OR = 0.57) were protective factors.Apgar score in 'one minute' of newborn infant was affected by several factors as stated above. Health care program in earlier period toward community parturient should be strengthened in order to discover and control high risk factors of duration of pregnancy in earlier period.

To investigate the status and influencing factors on knowledge, attitude and practice (KAP) about AIDS among the migrant workers in railway construction sites and to provide evidence for strategy development and measures on AIDS related health education and behavioral intervention.943 migrant workers in railway construction sites were surveyed. Univariate analysis, multivariate Logistic regression and correlation analysis were used to explore their influencing factors.The migrant workers in railway construction sites had poor AIDS knowledge as a whole. People with high educational level and income had higher AIDS correlative knowledge than other groups. Only 37.5% (275) of 734 migrant workers who had heard about AIDS felt pity for people with HIV/AIDS. There were 39.6%, 7.3% and 6.9% of 943 migrant workers did not object to "pre-marital sex", "prostitution" or "wenching". There were 90 (9.5%) migrant workers admitted having non-marital sex for the last three months but 22 (28.6%) admitted never using condoms,and only 8 (10.4%) had used each time. It appeared that the higher educational level and scores about AIDS knowledge one had,the higher the rate of using a condom. Both longer time interval away from their families and working time were, the lower they would usage a condom.Migrant workers in construction sites were potential high risk population for HIV/AIDS. AIDS health education and behavioral intervention should be carried out

BACKGROUND: Suicide is the leading cause of death among 15-34 year olds in China, but no national data are available on the suicide and suicide attempts rates of college students, a sub-group of youth with 23 million. Several studies have reported the prevalence of suicide attempts among college students, however, no meta-analysis pooling the prevalence of suicide attempts is found. OBJECTIVE AND METHODS: This study aims to estimate the pooled prevalence of suicide attempts among college students in China. The relevant studies up to August 2014 were systematically searched via electronic databases (PubMed-Medline, Embase, Chinese Wanfang database, Chinese National Knowledge Infrastructure and Chinese VIP database). We only selected original articles that either reported the prevalence of suicide attempts or sufficient data for calculating the prevalence. RESULTS: A total of 29 eligible studies, with 88,225 college students, were finally included. The maximum and minimum reported prevalences of suicide attempts among college students in China were 0.4% and 10.5%, respectively. The pooled prevalence of suicide attempts was 2.8% (95%CI: 2.3%-3.3%). Subgroup analyses showed that the pooled estimate of prevalence of life time suicide attempts was 2.7% (95%CI: 2.1%-3.3%), and 12-month suicide attempts was 2.9% (95%CI: 2.0%-3.8%). The prevalence for males was 2.4% (95%CI: 1.8%-3.0%), and for females was 2.7% (95%CI: 1.9%-3.7%). The prevalences among college students in grade 1 through 4 were 2.8% (95%CI: 1.7%-3.8%), 1.8% (95%CI: 1.2%-2.3%), 2.0% (95%CI: 0.8%-3.1%), and 2.9% (95%CI: 0.1%-6.7%), respectively. The prevalences among college students from rural and urban areas were 5.1% (95%CI: 2.8%-7.5%) and 3.7% (95%CI: 1.4%-5.9%), respectively. CONCLUSIONS: 2.8% prevalence of suicide attempts and more than 600,000 suicide attempters among college students indicate that suicide attempt among college students is an important public health problem in China. More attention should be paid to the current situation. Language: en

Aim: To describe the rates and patterns of unintentional injuries among primary and middle school students in China. Methods: A cross-sectional survey was conducted in Maanshan City of the Anhui Province in eastern China. All students attending six primary and four middle schools, selected randomly, were asked to report unintentional injuries occurring in the 12-mo period before the survey. The occurrence of unintentional injuries that resulted in medical attendance was summarized by study grade, sex, month and external causes. Results: The annual event-based injury rate per 100 students was higher among boys (21.7) than girls (17.6). Only 1.9% of the episodes resulted in hospitalization, and 17.8% resulted in missing school. The most frequent injuries were falls (38.2%) and transportation-related injuries (19.6%). The risk of injury was lower in middle schools than primary schools. Distribution by month of occurrence showed two peaks in boys during spring and autumn, but no clear peak was observed in girls. Conclusion: The descriptive epidemiology of unintentional injuries among students in China provides useful information on the distributions in person, place and time, which in turn provide hints for the further exploration of possible risk factors that are important in planning strategies for future prevention.

Objective To describe the rate and pattern of unintentional school injuries among primary and middle school students and to explore the major risk factors involved. Study design A cross-sectional survey of more than 10,000 students attending 6 primary and 4 middle schools selected randomly from all schools in Maanshan City of Anhui Province in eastern China was conducted to collect information on school injuries occurring in the 12-month period before the survey. Rate ratios for risk factors were estimated using the negative binomial regression analysis. Results The annual person-based school injury rate was 5.22 (95% CI: 3.90–6.53) percent. The annual event-based injury rate was 5.40 (95% CI: 4.04–6.76) per 100 students. Most injuries in school were relatively mild and only 1.53% (9/590) of the episodes resulted in hospitalization. The most frequent injures were falls (73%), and the most commonly injured sites were the upper limbs (46%). Male sex, primary school grades, poor health status, poor ability to concentrate, bad risk-taking behavior and high study-related stress were important risk factors. Conclusion This study provided useful baseline information on school injuries in China and identified important risk factors that would be important in planning prevention strategies.

To probe into the effects of familial factors on injury-related behaviors in children.Injury-related behaviors and familial factors of 6884 children were investigated with Family Questionnaire and Child Behavior Checklist. Multi-nominal logistic regression analysis was performed.There were 1670 (24.26%) children having serious injury-related behaviors and 3683 (53.50%) children having moderate injury-related behaviors. Factors contributing to children's injury-related behaviors would include punishment or indifference as well as the mode of parents' education; reintegral type of family; the level of parents' cognition on injuries; unfit location of medicine at home and careless attitudes of parents.There was close relationship between children's injury-related behaviors and familial factors. To avoid injury-related behaviors and to prevent injury occurrence, the importance of familial factors must be stressed.

This study examined the status of health-related behaviors among rural residents and the factors influencing the practice of such behaviors.One thousand and ninety subjects aged 15 years or over in a rural community, Anhui Province, China were surveyed. A questionnaire was used to collect information on the health knowledge, attitude and behavior of the subjects. Information on health behavior included smoking, drinking, dietary habits, regular exercises, sleeping pattern and oral health behavior.The prevalence of smoking and drinking in the male subjects was 46.5% and 46.9%, respectively. There was a positive significant association between smoking and drinking. Only 8.3% of all subjects ate three regular meals a day regularly. Among subjects who ate two meals a day, 89.7% did not have breakfast. Only 1.7% of subjects took part in regular exercise. About 85% of subjects slept 6 to 8 h per day. Only 38.4% of the respondents had the habit of hand washing before eating and after using the lavatory. 79.3% of the subjects brushed their teeth every day, and among them, only 10.6 percent brushed their teeth twice a day. Further analyses showed that 64.8% of subjects had 3-5 items of positive health behaviors out of 8 items and only 16.9% had six or more items. Logistical regression analyses suggested that better health behavior was affected by sex, age, years of education, income and health knowledge.The status of health behaviors among rural residents was generally poor. It is thus urgent to reinforce health education in rural communities in China.

Objective In order to avoid the misdiagnosis of thyroid diseases, we need to discuss the clinical features and diagnostic methods of cervical esophageal cancer and Zenker’s diverticulum. Methods The clinical and laboratory data of seven cases were reviewed retrospectively, and in all cases, esophageal-related diseases were misdiagnosed as thyroid diseases preoperatively. Among them, two cases were cervical esophageal cancer metastasized to thyroids but initially, they were misdiagnosed as thyroid cancer. The other five cases were Zenker’s diverticulum, but were originally diagnosed as nodular goiter, and two out of the five cases were found with calcification. They were all detected by ultrasound examination without any clinical feature of esophageal diseases. Previous literatures only reported five cases of thyroid metastasis and three cases of Zenker’s diverticulum. Results In both cases where cervical esophageal cancer metastasized to thyroid, anterior cervical neoplasm biopsy and surgical removal were performed followed by postoperative radiotherapy and chemotherapy. Both patients died from esophageal cancers in 7 and 15 months postoperatively. All five cases of Zenker’s diverticulum received excision and repair without any postoperative complication or recurrence in the following 2 to 7 years. Conclusions Cervical esophageal cancer and Zenker’s diverticulum may be misdiagnosed as thyroid disease. Careful and comprehensive diagnostic tests would be required to avoid misdiagnosis.