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Total quality management (TQM) is a management philosophy that focuses on continuous quality improvement across all parts of a company. Its key goals are to satisfy customers and stay in business. As a result, it's critical to identify the elements that lead to successful TQM implementation. This study also proposed a framework that helps organizations in their success. To achieve this goal, various critical success factors (CSFs) that contribute to organizational growth success were identified. The major purpose of this research is to identify critical success factors for TQM implementation in the manufacturing industry. For this aim, the study was deployed from an extensive literature review, and the questionnaire was used as a research instrument to specify the essential CSFs in different manufacturing industries. Around 300 questionnaires were issued to top management of manufacturing enterprises in Sindh Pakistan (both public and commercial sectors). The structured survey received 82 valid responses, which were then analyzed by using factor analysis. Finally, the study's findings highlighted the five CSFs (customer satisfaction, employee involvement, training and education, continuous improvement, employee encouragement, and service quality) as the most important aspects in building an effective framework for successful TQM adoption in manufacturing industries. The findings of this study will assist senior management in the implementation of a TQM program and resource allocation that will produce the greatest results in terms of increased returns and stakeholder value.