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Start Over Author "Kojima, Shinji" Topic materials chemistry
4 results on '"Kojima, Shinji"'

2. Ruthenium complexes carrying a disialo complex-type oligosaccharide: enzymatic synthesis and its application to a luminescent probe to detect influenza viruses

Author

Teruaki Hasegawa, Yasuo Suzuki, Kojima Shinji, Yutaka Makimura, Takahiro Yonemura, Kazukiyo Kobayashi, Ken Sasaki, Kenji Yamamoto, Takashi Suzuki, and Tadanobu Takahashi

Subjects
inorganic chemicals, chemistry.chemical_classification, Luminescence, Metals and Alloys, Oligosaccharides, chemistry.chemical_element, General Chemistry, Oligosaccharide, Complex type, Enzymatic synthesis, Orthomyxoviridae, Combinatorial chemistry, Ruthenium, Catalysis, Enzymes, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, Molecular Probes, Materials Chemistry, Ceramics and Composites, Organic chemistry
Abstract

Tris-bipyridine ruthenium-complexes carrying a disialo complex-type oligosaccharide were prepared via a one-pot transglycosylation using endo-glycosidase (Endo M); they bind to type-A influenza viruses with excellent affinity (IC50 = 8.4 microM), and their luminescence intensity is strongly depressed by virus-binding.

Published
2003
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