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Your search keyword '"Nutlin-3a"' showing total 26 results

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26 results on '"Nutlin-3a"'

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2. MDM2 up-regulates the energy metabolism in NSCLC in a p53-independent manner.

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3. Resistance mechanisms to inhibitors of p53-MDM2 interactions in cancer therapy: can we overcome them?

4. Resistance mechanisms to inhibitors of p53-MDM2 interactions in cancer therapy: can we overcome them?

5. Nutlin‐3a as a novel anticancer agent for adrenocortical carcinoma with CTNNB1 mutation

6. MDM2/p53通路对多发性骨髓瘤RPMI 8226 细胞凋亡的调控.

8. Inhibition of Transglutaminase 2 but Not of MDM2 Has a Significant Therapeutic Effect on Renal Cell Carcinoma

9. Nutlin‐3a as a novel anticancer agent for adrenocortical carcinoma with <italic>CTNNB1</italic> mutation.

10. P53-MDM2 PATHWAY: EVIDENCES FOR A NEW TARGETED THERAPEUTIC APPROACH IN B-ACUTE LYMPHOBLASTIC LEUKEMIA

11. P53-MDM2 Pathway: Evidences for A New Targeted Therapeutic Approach in B-Acute Lymphoblastic Leukemia.

12. Inhibition of Transglutaminase 2 but Not of MDM2 Has a Significant Therapeutic Effect on Renal Cell Carcinoma

13. Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53

14. The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant.

15. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.

16. Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line

17. Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals

18. Nutlin-3a as a novel anticancer agent for adrenocortical carcinoma with CTNNB1 mutation

19. Nutlin-3a Nanodisks Induce p53 Stabilization and Apoptosis in a Subset of Cultured Glioblastoma Cells

20. Nutlin-3a selects for cells harbouring TP53 mutations

21. Inhibition of Transglutaminase 2 but Not of MDM2 Has a Significant Therapeutic Effect on Renal Cell Carcinoma.

22. Regulation of p53-dependent genes expression in multiple sclerosis: the effect of MDM2 inhibitor Nutlin-3a

23. Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: A new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients

24. Nutlin-3a is a potential therapeutic for Ewing sarcoma

25. Normal human mammary epithelial cells proliferate rapidly in the presence of elevated levels of the tumor suppressors p53 and p21WAF1/CIP1.

26. Normal human mammary epithelial cells proliferate rapidly in the presence of elevated levels of the tumor suppressors p53 and p21WAF1/CIP1.