1. Effective Combination of Different Surgical Strategies for Deep Sternal Wound Infection and Mediastinitis.
- Author
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Tewarie L, Moza AK, Khattab MA, Autschbach R, and Zayat R
- Subjects
- Age Factors, Aged, Aged, 80 and over, Female, Humans, Male, Mediastinitis diagnosis, Mediastinitis microbiology, Mediastinitis mortality, Middle Aged, Recurrence, Reoperation, Retrospective Studies, Risk Factors, Sternotomy mortality, Surgical Wound Infection diagnosis, Surgical Wound Infection microbiology, Surgical Wound Infection mortality, Time Factors, Treatment Outcome, Mediastinitis surgery, Omentum surgery, Pectoralis Muscles surgery, Sternotomy adverse effects, Surgical Flaps adverse effects, Surgical Wound Infection surgery, Wound Closure Techniques adverse effects, Wound Closure Techniques mortality
- Abstract
Purpose: Timing and ideal reconstructive approach in deep sternal wound infection (DSWI) and mediastinitis still remain controversially debated. We present our own combined surgical strategy of bilateral pectoralis major muscle flap (BPMMF) or omental flap (OF) transposition., Methods: Between July 2010 and July 2016, poststernotomy patients with DSWI and mediastinitis underwent a secondary wound closure with modified BPMMF (Group A, center for disease control class (CDC)-II, n = 21; Group B, CDC-III, n = 20) or with OF (Group C, CDC-III, n = 19) following vacuum-assisted closure (VAC)., Results: Significant risk factors for mediastinitis (CDC-III) were chronic obstructive pulmonary disease (COPD; p = 0.001), peripheral arterial disease (PAD; p = 0.012), cardiopulmonary bypass (CPB) time (p = 0.027), total operation time (p = 0.039), total intensive care unit (ICU) stay (p = 0.011), and blood transfusion (p = 0.049). Mean antibiotic therapy (18.4 ± 8.8[B] vs. 36.2 ± 24.4[C] days, p = 0.026) and length of hospitalization (25.2 ± 12.1[B] vs 53.8 ± 18.5 days[C], p = 0.053) were significantly longer in group C. In-hospital death was 3/19 (15.8%) in group C versus 0 in group B (p = 0.026). Frequency of recurrent mediastinitis was equal (p = 0.92); however, complications occurred more often in group C (31.6% vs. 0%, p = 0.031). The mean follow-up time was 111 ± 62 days., Conclusion: In younger (<70 years) patients without sternal bone necrosis, the BPMMF is superior to the OF technique with relatively low recurrence and mortality risks.
- Published
- 2019
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