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Paying attention to climate elements that are mainly represented in the variation of ventilation systems is due to its impact on the indoor environmental quality and therefore its effect on the occupants and their activities. Consequently, the definition of the indoor environmental quality has extended beyond the concept of recognized design standards to include the mixing of architectural design with various environmental factors. The aim of this study is to assess the efficiency of hybrid ventilation and its effect on the indoor temperature and energy consumption rates in ward patient rooms in the Aswan Insurance Hospital. In order to improve the thermal performance to achieve thermal comfort as the most effective element within the health spaces of the elements of the indoor environmental quality based on a questionnaire conducted on 308 individuals, including patients, visitors and health care providers within the health facilities in Aswan. The related problems of ventilation systems (natural and mechanical) are the root case, as it is difficult to control indoor air temperature and increase the percentage of carbon dioxide as well as energy consumption. For achieving the aim of this study, the simulation program (design builder) was utilized to measure room temperature, relative humidity, co2 production and energy consumption in different ventilation conditions. The results of the study showed the ability of hybrid ventilation to reduce the room temperature, especially in summer to reach (3.5 K) .Carbon dioxide and energy consumption were fallen by a margin (90 Kg/m2), (290.9 Kwh/m2) respectively. The study also included some suggestions for the location and area of the ventilation outlet to achieve both of better natural ventilation and hybrid ventilation, which resulted in a higher rate of air change and thus increase the movement of air in the vacuum. It recommended that control strategies for hybrid ventilation should be studied in order to be familiar with all developments and to be used mainly within health facilities. [ABSTRACT FROM AUTHOR]