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Your search keyword '"Yiming, Adilijiang"' showing total 3 results
Start Over Author "Yiming, Adilijiang" Topic medicine, chinese traditional
3 results on '"Yiming, Adilijiang"'

1. Changes of microRNA profile after Yimusake treatment in ED rat model.

Author

Jiang P, Aimaier M, Maimaitiyiming M, Liu F, Ma W, Sataer M, Amuti S, Wang T, and Yiming A

Subjects
Animals, Erectile Dysfunction genetics, Erectile Dysfunction physiopathology, Male, Penis metabolism, Penis physiopathology, Rats, Rats, Sprague-Dawley, Tablets, Treatment Outcome, Disease Models, Animal, Erectile Dysfunction therapy, Gene Expression Profiling methods, Medicine, Chinese Traditional methods, MicroRNAs genetics
Published
2019
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2. Research on the establishment of chronic stress-induced premature ovarian failure the rat model and effects of Chinese medicine Muniziqi treatment.

Author

Keremu A, Yaoliwasi A, Tuerhong M, Kadeer N, Heyi, Yiming A, and Yilike X

Subjects
Animals, Chronic Disease, Disease Models, Animal, Female, Primary Ovarian Insufficiency etiology, Primary Ovarian Insufficiency pathology, Primary Ovarian Insufficiency physiopathology, Rats, Rats, Sprague-Dawley, Stress, Psychological complications, Stress, Psychological pathology, Stress, Psychological physiopathology, Medicine, Chinese Traditional, Primary Ovarian Insufficiency therapy, Stress, Psychological therapy
Abstract

The purposes of this study were to establish and to explore the biological basis of the chronic stress-induced premature ovarian failure (POF) model and to explore the therapeutic effects of the traditional Chinese medicine Muniziqi. Sexually matured female Sprague-Dawley rats were fed with spinach and cilantro in cold and wet conditions for about 20 weeks until a chronic stress (CS) model was established. The CS rats were divided into a POF stress model group and a stress model group according to weekly biological characteristics and hormone level detection ( luteinizing hormone [LH], follicle stimulating hormone [FSH], and estrogen [E2]). To investigate the therapeutic effect of Muniziqi, the POF disease stress model group was divided into the high-, medium-, and low-drug intervention groups. The results showed that chronic stresses (special food, cold, damp) can lead to POF disease. The traditional Chinese medicine Muniziqi could not only improve the reproductive hormone level disorder, but also improve the function of the hypothalamus-pituitary-ovarian axis. The underlying mechanism may be a change in the E2, LH, and FSH hormone levels in serum and lower expression of ovarian premature aging-related protein PFN-1., (© 2018 Wiley Periodicals, Inc.)

Published
2019
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3. [Expressions of calcitonin gene-related peptide and vasoactive intestinal peptide in the penile tissue of the ED rat model and their action mechanisms]

Author

Feng-Xia, Liu, Ruze, Abudureyimujiang, Maimaitiyiming, Maowulan, Liu-Ying, Zhuyan, Aihaiti, Nizamu, Pan-Pan, Zhang, and Yiming, Adilijiang

Subjects
Calcitonin, Male, Rats, Sprague-Dawley, Erectile Dysfunction, Calcitonin Gene-Related Peptide, Animals, Down-Regulation, Medicine, Chinese Traditional, Penis, Rats, Vasoactive Intestinal Peptide
Abstract

To determine the expressions of calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP) in the penile tissue of the ED rat model and explore their action mechanisms.An ED model was established in 44 mature male SD rats by feeding them on a spinach + coriander diet in a cold-wet environment and another 10 were taken as normal controls. Then the model rats were randomly divided into an ED model control group (n = 15) treated by gavage of distilled water in the same modeling environment, a spontaneous recovery group (n = 15) treated by gavage of distilled water in the normal environment, and a medication group (n = 14) treated intragastrically with Yimusake Tablets at 250 mg/kg qd. After 2－3 weeks of intervention, the expressions of CGRP and VIP in the penile tissue were detected by immunohistochemistry and Western blot.Immunohistochemistry showed that, after 2 weeks of intervention, both the expressions of CGRP and VIP in the rat penile tissue were significantly lower in the ED model control (150.0 ± 43.3 and 36.4 ± 13.1) and the spontaneous recovery group (165.9 ± 40.7 and 67.5 ± 29.0) than in the normal control (227.3 ± 42.5 and 175.0 ± 45.6) (P0.05), but remarkably higher in the medication group (255.0 ± 38.7 and 167.5 ± 42.6) than those in the ED model control and spontaneous recovery groups (P0.05).The expressions of CGRP and VIP were significantly down-regulated in the ED rat model, and Yimusake Tablets improved ED by up-regulating their expressions.

Published
2020

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