6 results on '"Ashita Sharma"'
Search Results
2. Bioactivities of phytochemicals present in tomato
- Author
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Ashita Sharma, Poonam Chaudhary, Avinash Kaur Nagpal, and Balwinder Singh
- Subjects
0301 basic medicine ,chemistry.chemical_classification ,Vitamin ,Tomatine ,Antioxidant ,medicine.medical_treatment ,Carotene ,fungi ,food and beverages ,Review Article ,Biology ,Ascorbic acid ,Lycopene ,03 medical and health sciences ,Ingredient ,chemistry.chemical_compound ,030104 developmental biology ,0302 clinical medicine ,chemistry ,030220 oncology & carcinogenesis ,medicine ,Food science ,Carotenoid ,Food Science - Abstract
Tomato is a wonder fruit fortified with health-promoting phytochemicals that are beneficial in preventing important chronic degenerative disorders. Tomato is a good source of phenolic compounds (phenolic acids and flavonoids), carotenoids (lycopene, α, and β carotene), vitamins (ascorbic acid and vitamin A) and glycoalkaloids (tomatine). Bioactive constituents present in tomato have antioxidant, anti-mutagenic, anti-proliferative, anti-inflammatory and anti-atherogenic activities. Health promoting bioactivities of tomatoes make them useful ingredient for the development of functional foods. Protective role of tomato (lycopene as a potent antioxidant) in humans against various degenerative diseases are known throughout the world. Intake of tomato is inversely related to the incidence of cancer, cardiovascular diseases, ageing and many other health problems. Bioavailability of phytoconstituents in tomato is generally not affected by routine cooking processes making it even more beneficial for human consumption. The present review provides collective information of phytochemicals in tomato along with discussing their bioactivities and possible health benefits.
- Published
- 2018
3. Palynological studies of some roadside plants under exposure to traffic stress
- Author
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Rajwant Kaur, Mandeep Kaur, Jatinder Kaur Katnoria, Avinash Kaur Nagpal, and Ashita Sharma
- Subjects
0106 biological sciences ,Pollution ,media_common.quotation_subject ,Immunology ,Air pollution ,Plant Science ,010501 environmental sciences ,medicine.disease_cause ,010603 evolutionary biology ,01 natural sciences ,chemistry.chemical_compound ,Cassia ,Pollen ,Botany ,medicine ,Immunology and Allergy ,0105 earth and related environmental sciences ,media_common ,Pollutant ,Palynology ,Thevetia ,biology ,Tetrazolium chloride ,food and beverages ,biology.organism_classification ,Horticulture ,chemistry - Abstract
The diverse pollutants emitted from automobiles can have adverse effects on the health and survival of plants, animals and human beings. Different plant species have been known to possess high potential of absorption, detoxification and tolerance of high levels of pollution. Considering this, the present study was carried out to assess the impact of automobile pollution on palynology of roadside plants. Three species, viz. Cannabis sativa, Cassia fistula and Thevetia peruviana growing along the roadsides of nine sites of Amritsar city under different levels of traffic stress were selected for the study. Pollen viability and pollen size were studied by staining pollen with 2,3,5-triphenyl tetrazolium chloride stain and observed under light microscope. Scanning electron microscope was used to study the changes in morphology of the pollen grains. It was observed that the percentage of pollen viability of three species was inversely proportional to the load of traffic at a particular site. Pollen viability was observed to be minimum (C. sativa—22.58 %; C. fistula—21.30 %; and T. peruviana—6.22 %) for the plants of the three species studied growing at traffic site I, site with heavy traffic load as compared to plants growing at sites with comparatively lesser traffic load. C. sativa growing at traffic site IV showed maximum pollen viability of 79.74 %, while C. fistula and T. peruviana growing at traffic site VIII exhibited maximum pollen viability of 83.32 and 68.78 %, respectively. Pollen size and morphology did not show any significant variation and remained unaffected with the increase in traffic stress.
- Published
- 2015
4. Polyphenols in Food: Cancer Prevention and Apoptosis Induction
- Author
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Ashita Sharma, Mandeep Kaur, Jatinder Kaur Katnoria, and Avinash Kaur Nagpal
- Subjects
0301 basic medicine ,Male ,Antioxidant ,medicine.medical_treatment ,Antineoplastic Agents ,Apoptosis ,medicine.disease_cause ,Biochemistry ,Antioxidants ,03 medical and health sciences ,0302 clinical medicine ,In vivo ,Cell Line, Tumor ,Neoplasms ,Drug Discovery ,medicine ,Hydroxybenzoates ,Animals ,Anticarcinogenic Agents ,Humans ,Pharmacology ,chemistry.chemical_classification ,Reactive oxygen species ,Cancer prevention ,Chemistry ,Organic Chemistry ,food and beverages ,Cancer ,Polyphenols ,medicine.disease ,030104 developmental biology ,Polyphenol ,Food ,Resveratrol ,030220 oncology & carcinogenesis ,Cancer cell ,Molecular Medicine ,Carcinogenesis - Abstract
Polyphenols are a group of water-soluble organic compounds, mainly of natural origin. The compounds having about 5-7 aromatic rings and more than 12 phenolic hydroxyl groups are classified as polyphenols. These are the antioxidants which protect the body from oxidative damage. In plants, they are the secondary metabolites produced as a defense mechanism against stress factors. Antioxidant property of polyphenols is suggested to provide protection against many diseases associated with reactive oxygen species (ROS), including cancer. Various studies carried out across the world have suggested that polyphenols can inhibit the tumor generation, induce apoptosis in cancer cells and interfere in progression of tumors. This group of wonder compounds is present in surplus in natural plants and food products. Intake of polyphenols through diet can scavenge ROS and thus can help in cancer prevention. The plant derived products can also be used along with conventional chemotherapy to enhance the chemopreventive effects. The present review focuses on various in vitro and in vivo studies carried out to assess the anti-carcinogenic potential of polyphenols present in our food. Also, the pathways involved in cancer chemopreventive effects of various subclasses (flavonoids, lignans, stilbenes and phenolic acids) of polyphenols are discussed.
- Published
- 2017
5. Family Fabaceae: A Boon for Cancer Therapy
- Author
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Avinash Kaur Nagpal, Jatinder Kaur Katnoria, Ashita Sharma, Rajwant Kaur, and Rajinder Kaur
- Subjects
Traditional medicine ,010405 organic chemistry ,fungi ,Cancer therapy ,food and beverages ,Cancer ,Disease ,Biology ,medicine.disease ,medicine.disease_cause ,01 natural sciences ,0104 chemical sciences ,03 medical and health sciences ,Human health ,0302 clinical medicine ,Phytochemical ,030220 oncology & carcinogenesis ,Botany ,medicine ,Carcinogenesis ,Family Fabaceae - Abstract
Cancer is a deadliest disease which has been a challenging prorogue for human health and civilization. Legumes or plants of family Fabaceae have been part of our diet since times immemorial. Plants of this family are rich in phytoconstituents which make them effective therapeutic agents for various diseases. The synergistic effects of different phytoconstituents are far more than the effect of individual compounds. Studies have revealed that those parts of the world which consume legumes as a staple diet have less mortality due to cancer as compared to other parts of the world. Also, it has been reported that phytochemical components of plants of this family inhibit carcinogenesis at various stages. The use of phytoconstituents derived from these plants along with traditional chemotherapy can have synergistic effects which help in fighting cancer. This review focuses on various compounds present in plants of family Fabaceae and their anticarcinogenic potential.
- Published
- 2017
6. Allium cepa Root Chromosomal Aberration Assay: An Application in Assessing Anti-genotoxic Potential of Ashwagandha
- Author
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Rajneet Kour Soodan, Jatinder Kaur Katnoria, Mandeep Kaur, Avinash Kaur Nagpal, and Ashita Sharma
- Subjects
food.ingredient ,Traditional medicine ,fungi ,food and beverages ,Biology ,medicine.disease_cause ,biology.organism_classification ,food ,Herb ,Botany ,medicine ,Bioassay ,Allium ,High potential ,Genotoxicity - Abstract
Plant kingdom is rich in phytochemicals with high potential for medicinal and therapeutic uses. These can be particularly recruited to combat the environmental genotoxins that have increased tremendously in last few decades due to industrialization of human lifestyle. Screening of plants for this purpose involves a battery of bioassays; the mammalian or bacterial assays are used worldwide. Considering the ethical and economic reasons, the use of plant bioassays for the initial screening is advocated. Of all plant bioassays available, Allium cepa root chromosomal aberration assay is an efficient, most-easy and inexpensive tool that can be used for (i) assessment of genotoxicity of environmental mutagens and (ii) evaluation of anti-genotoxic potential of plant extracts. The present chapter discusses the history, application and technical aspects of this assay in assessing the geno-protective potential of various plants with special reference to Ashwagandha, the wonder herb.
- Published
- 2017
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